Effects of MEDI-522 On Disease Activity and Progression of Joint Damage in Patients With Active Rheumatoid Arthritis Suboptimally Responding to Methotrexate
Public ClinicalTrials.gov record NCT00069017. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Randomized, Double-Blind Study to Evaluate the Effects of MEDI-522, a Humanized MAb to Integrin Alpha V Beta 3, On Disease Activity and Progression of Joint Damage in Pts With Active Rheumatoid Arthritis Suboptimally Responding to Methotrexate
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To compare, as a preliminary analysis, the effects of MEDI-522 versus placebo at 6 months on disease activity (ACR20) and progression of structural joint damage.
Study identification
- NCT ID
- NCT00069017
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 300 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2003 (Type not available)
- Primary completion
- Not listed
- Completion
- Apr 2006 (Actual)
- Last update posted
- Nov 27, 2007
2003 – 2006
United States locations
- U.S. sites
- 29
- U.S. states
- 15
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The University of Alabama at Birmingham | Birmingham | Alabama | 35249-7201 | — |
| Sun Valley Arthritis Center | Glendale | Arizona | 85308 | — |
| Arizona Research & Education | Phoenix | Arizona | 85012 | — |
| University of Arizona | Tucson | Arizona | 85724 | — |
| Fayetteville Diagnostic Clinic, Ltd. | Fayetteville | Arkansas | 72703 | — |
| Thornton Hospital | La Jolla | California | 92037-0943 | — |
| Boling Clinical Trials | Rancho Cucamonga | California | 91730 | — |
| Pacific Arthritis Center Medical Group | Santa Maria | California | 93454 | — |
| Arthritis and Rheumatic Disease Specialty | Aventura | Florida | 33180 | — |
| Centre for Rheumatology, Immunology & Arthritis | Fort Lauderdale | Florida | 33334 | — |
| Ocala Rheumatology Research Center | Ocala | Florida | 34474 | — |
| Sarasota Arthritis Research Center | Sarasota | Florida | 34239 | — |
| Sanford S. Hartman | Decatur | Georgia | 30033 | — |
| Center for Rheumatology and Bone Research | Wheaton | Maryland | 20902 | — |
| RIMA | St Louis | Missouri | 63131 | — |
| Arthritis Consultants, Inc. | St Louis | Missouri | 63141 | — |
| Rheumatology Associates of New Jersey | Teaneck | New Jersey | 07666 | — |
| The Center for Rheumatology | Albany | New York | 12206 | — |
| Health Research Institute | Oklahoma City | Oklahoma | 73109 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Oklahoma Center for Arthritis Therapy and Research Inc. | Tulsa | Oklahoma | 74114 | — |
| Amarillo Center for Clinical Research | Amarillo | Texas | 79124 | — |
| Radiant Research | Dallas | Texas | 75235 | — |
| Arthritis & Osteoporosis Associates, LLP | Lubbock | Texas | 79410 | — |
| University of Utah Medical Hospital | Salt Lake City | Utah | 84132 | — |
| The Physician's Clinic of Spokane | Spokane | Washington | 99204 | — |
| Rheumatology Northwest/Clinical Trials Northwest | Yakima | Washington | 98902 | — |
| Gundersen Clinic Ltd. | La Crosse | Wisconsin | 54601 | — |
| University of Wisconsin Hospital & Clinics | Madison | Wisconsin | 53792-3244 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00069017, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 27, 2007 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00069017 live on ClinicalTrials.gov.