Satraplatin in Hormone Refractory Prostate Cancer Patients Previously Treated With One Cytotoxic Chemotherapy Regimen
Public ClinicalTrials.gov record NCT00069745. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-National Phase III Study of Satraplatin Plus Prednisone or Placebo Plus Prednisone in Patients With Hormone Refractory Prostate Cancer Previously Treated With One Cytotoxic Chemotherapy Regimen
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
PURPOSE: The SPARC trial is designed to compare the combination of the investigational oral cytotoxic drug, satraplatin, and prednisone, versus prednisone alone as second line chemotherapy in patients with hormone-refractory prostate cancer (HRPC). TARGET PATIENT POPULATION: The SPARC trial is intended for patients who have hormone-refractory prostate cancer (HRPC) and whose disease has progressed after treatment with one chemotherapy regimen. Please refer to the Eligibility Criteria page for the key inclusion and exclusion criteria. WHAT IS SATRAPLATIN: Satraplatin is a member of the platinum-based class of chemotherapy drugs. Platinum-based drugs have been clinically proven to be one of the most effective classes of anticancer therapies. Unlike the currently marketed platinum-based drugs, satraplatin can be given orally. Satraplatin is also the only platinum-based drug that has demonstrated efficacy against prostate cancer in a randomized trial. RATIONALE: There are currently no approved chemotherapy drugs for the second line treatment of hormone-refractory prostate cancer (HRPC). In a preliminary randomized trial conducted in Europe, the combination of satraplatin and prednisone had superior activity compared to prednisone alone, for the treatment of HRPC patients who had not previously been treated with chemotherapy
Study identification
- NCT ID
- NCT00069745
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- Not listed
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2003 (Type not available)
- Primary completion
- Jan 2006 (Actual)
- Completion
- Mar 2007 (Actual)
- Last update posted
- Aug 7, 2012
2003 – 2007
United States locations
- U.S. sites
- 105
- U.S. states
- 32
- U.S. cities
- 93
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Birmingham Hematology and Oncology | Birmingham | Alabama | 35205 | — |
| Birmingham Hematology and Oncology | Birmingham | Alabama | 35235 | — |
| Hematology Oncology Associates | Phoenix | Arizona | 85012 | — |
| Northern AZ Hematology & Oncology Assoc. | Sedona | Arizona | 86336 | — |
| Hematology Oncology Physicians/SMO | Tucson | Arizona | 85712 | — |
| Arizona Cancer Center | Tuscon | Arizona | 85724 | — |
| California Cancer Center | Fresno | California | 93720 | — |
| Pacific Shores Medical Group | Long Beach | California | 90813 | — |
| Division of Hematology - Oncology | Los Angeles | California | 90095-7187 | — |
| University of California Davis Cancer Center, Division of Hematology-Oncology | Sacramento | California | 95817 | — |
| Sharp Healthcare - Clinical Oncology Research | San Diego | California | 92123 | — |
| Rocky Mountain Cancer Center - Midtown | Denver | Colorado | 80218 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| DeQuattro Community Cancer Center | Manchester | Connecticut | 06040 | — |
| Cancer Centers of Florida-Altamonte | Altamonte Springs | Florida | 34761 | — |
| The Center for Hematology Oncology | Boca Raton | Florida | 33486 | — |
| Hematology/Oncology Group of South Florida | Miami | Florida | 33176 | — |
| Innovative Medical Research of South Florida | Miami Shores | Florida | 33179 | — |
| Florida Cancer Institute | New Port Richey | Florida | 34655 | — |
| Ocala Oncology Center | Ocala | Florida | 34474 | — |
| South Florida Oncology & Hematology | Plantation | Florida | 33324 | — |
| Hematology/Oncology Associates of Treasure Coast | Port Saint Lucie | Florida | 34952 | — |
| Oncology and Hematology Associates of West Broward P.A. | Tamarac | Florida | 33321 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Northwest Medical Specialists | Niles | Illinois | 60714 | — |
| North Shore Research Association | Skokie | Illinois | 60076 | — |
| Central Indiana Cancer Centers | Fishers | Indiana | 46227 | — |
| Indiana Hematology Oncology Consultants | Indianapolis | Indiana | 46202 | — |
| Central Indiana Cancer Centers | Indianapolis | Indiana | 46227 | — |
| Oncology Associates of Cedar Rapids | Cedar Rapids | Iowa | 52403 | — |
| Kansas City Cancer Centers - Southwest | Overland Park | Kansas | 66210 | — |
| Louisiana Oncology Associates | Lafayette | Louisiana | 70506 | — |
| LSU Health Science Center, Stanley S. Scott Cancer Center | New Orleans | Louisiana | 70112 | — |
| Maine Center for Cancer Medicine & Blood Disorders | Scarborough | Maine | 04074 | — |
| Berkshire Hematology Oncology | Pittsfield | Massachusetts | 01201 | — |
| Karmanos Cancer Institute, Wayne State University | Detroit | Michigan | 48201 | — |
| Maplewood Cancer Center | Maplewood | Minnesota | 55404 | — |
| Virginia Piper Cancer Institute | Minneapolis | Minnesota | 55407 | — |
| Missouri Cancer Associates | Columbia | Missouri | 65201 | — |
| Capitol Comprehensive Cancer Care Clinic | Jefferson City | Missouri | 65109 | — |
| St. Joseph Oncology, Inc. | Saint Joseph | Missouri | 64507 | — |
| Hematology/Oncology Consultants, Inc. | St Louis | Missouri | 63136 | — |
| Arch Medical Services, Inc. | Washington | Missouri | 63090 | — |
| Nebraska Methodist Hospital Cancer Center | Omaha | Nebraska | 68114 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89109 | — |
| Nevada Cancer Institute | Las Vegas | Nevada | 89135 | — |
| New Hampshire Oncology-Hematology PA | Hooksett | New Hampshire | 03106 | — |
| Hematology Oncology Associates | Albuquerque | New Mexico | 87106 | — |
| Lovelace Sandia Health Systems | Albuquerque | New Mexico | 87108 | — |
| Veterans Affairs Medical Center | Albuquerque | New Mexico | 87108 | — |
| The University of New Mexico | Albuquerque | New Mexico | 87131-0001 | — |
| New Mexico Cancer Care Associates | Santa Fe | New Mexico | 87505 | — |
| Albany Regional Cancer Center | Albany | New York | 12208 | — |
| New York Oncology Hematology, P.C. | Albany | New York | 12208 | — |
| Advanced Oncology Associates | Armonk | New York | 10504 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Interlakes Oncology Hematology | Canandaigua | New York | 14623 | — |
| Columbia Presbyterian Medical Center | New York | New York | 10032 | — |
| New York Oncology Hematology | Rexford | New York | 12148 | — |
| VA Medical Center Syracuse | Syracuse | New York | 13210 | — |
| Raleigh Hematology Oncology Clinic | Cary | North Carolina | 27511 | — |
| Piedmont Hematology - Oncology | Winston-Salem | North Carolina | 27103 | — |
| Dayton Oncology Hematology | Kettering | Ohio | 45067 | — |
| Cancer Care Associates | Oklahoma City | Oklahoma | 73120 | — |
| Cancer Care Associates | Tulsa | Oklahoma | 74136 | — |
| Willamette Valley Cancer Center | Eugene | Oregon | 97401 | — |
| Hematology and Oncology Associates of Northeastern PA / PC | Dunmore | Pennsylvania | 18512 | — |
| University of Pennsylvania Abramson Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh Cancer Institute- Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | — |
| Charleston Cancer Center | Charleston | South Carolina | 29406 | — |
| Medical University of South Carolina Hollings Cancer Center | Charleston | South Carolina | 29425 | — |
| Cancer Center of the Carolinas, Seneca | Seneca | South Carolina | 29672 | — |
| The West Clinic | Memphis | Tennessee | 38120 | — |
| Texas Cancer Center | Abilene | Texas | 79606 | — |
| Texas Oncology | Arlington | Texas | 76012 | — |
| Southwest Regional Cancer Center | Austin | Texas | 78705 | — |
| Texas Oncology Cancer Center | Austin | Texas | 78731 | — |
| Mamie McFaddin Ward Cancer Center | Beaumont | Texas | 77702 | — |
| Texas Onoclogy PA - Bedford | Bedford | Texas | 76022 | — |
| Texas Cancer Center at Medical City | Dallas | Texas | 75230 | — |
| Texas Oncology, P.A. | Dallas | Texas | 75231-1449 | — |
| The Texas Cancer Center | Dallas | Texas | 75237 | — |
| TOPA Sammons Cancer Center | Dallas | Texas | 75246 | — |
| Texas Cancer Center | Denton | Texas | 76210 | — |
| El Paso Cancer Treatment Center | El Paso | Texas | 79915 | — |
| Texas Oncology, P.A. | Fort Worth | Texas | 76104 | — |
| San Antonio Tumor & Blood Clinic | Fredericksburg | Texas | 78624 | — |
| Texas Oncology, P.A. | Garland | Texas | 75042 | — |
| Texas Oncology, P.A. - Irving | Irving | Texas | 75601 | — |
| Lake Vista Cancer Center | Lewisville | Texas | 75067 | — |
| Longview Cancer Center | Longview | Texas | 75601 | — |
| S. Texas Cancer Center | McAllen | Texas | 78503 | — |
| Texas Cancer Center of Mesquite | Mesquite | Texas | 75150 | — |
| Allison Cancer Center | Midland | Texas | 79701 | — |
| West Texas Cancer Center | Odessa | Texas | 79761 | — |
| Hematology Oncology Associates of South Texas | San Antonio | Texas | 78229 | — |
| Tyler Cancer Center | Tyler | Texas | 75702 | — |
| Waco Cancer Care Research Center | Waco | Texas | 76712 | — |
| Texas Oncology, P.A. - Deke Slayton Cancer Center | Webster | Texas | 77598 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23501 | — |
| Onc and Hem Associates of SW VA, Inc. | Salem | Virginia | 24153 | — |
| Puget Sound Cancer Center - Edmonds | Edmonds | Washington | 98026 | — |
| Cancer Care Northwest-North | Spokane | Washington | 99218 | — |
| Northwest Cancer Specialists | Vancouver | Washington | 98684 | — |
| Froedtert Memorial Lutheran Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 106 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00069745, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 7, 2012 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00069745 live on ClinicalTrials.gov.