ClinicalTrials.gov record
Gemtuzumab Ozogamicin in Treating Young Patients With Newly Diagnosed Acute Myeloid Leukemia Undergoing Remission Induction and Intensification Therapy
ClinicalTrials.gov ID: NCT00070174
Public ClinicalTrials.gov record NCT00070174. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Treatment of Newly Diagnosed Childhood Acute Myeloid Leukemia (AML) Using Intensive MRC-Based Therapy and Gemtuzumab Ozogamicin (GMTZ): A COG Pilot Study
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Giving chemotherapy before a donor bone marrow transplant helps stop the growth of cancer cells. It also helps stop the patient's immune system from rejecting the donor's stem cells. Also, monoclonal antibodies, such as gemtuzumab ozogamicin, can find cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. When the healthy stem cells from a donor are infused into the patient they may help the patient's bone marrow make stem cells, red blood cells, white blood cells, and platelets. PURPOSE: This phase II trial is studying how well gemtuzumab ozogamicin works in treating young patients who are undergoing remission induction, intensification therapy, and allogeneic bone marrow transplant for newly diagnosed acute myeloid leukemia.
Study identification
- NCT ID
- NCT00070174
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 350 participants
Conditions and interventions
Conditions
Interventions
- asparaginase Drug
- busulfan Drug
- cyclophosphamide Drug
- cyclosporine Drug
- cytarabine Drug
- daunorubicin hydrochloride Drug
- etoposide Drug
- gemtuzumab ozogamicin Drug
- methotrexate Drug
- mitoxantrone hydrochloride Drug
- allogeneic bone marrow transplantation Procedure
Drug · Procedure
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2003 (Type not available)
- Primary completion
- Sep 2006 (Actual)
- Completion
- Dec 2013 (Actual)
- Last update posted
- Feb 20, 2014
2003 – 2013
United States locations
- U.S. sites
- 134
- U.S. states
- 45
- U.S. cities
- 114
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Comprehensive Cancer Center at University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Phoenix Children's Hospital | Phoenix | Arizona | 85016-7710 | — |
| Arkansas Cancer Research Center at University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Southern California Permanente Medical Group | Downey | California | 90242-2814 | — |
| Loma Linda University Cancer Institute at Loma Linda University Medical Center | Loma Linda | California | 92354-2870 | — |
| Jonathan Jaques Children's Cancer Center at Miller Children's Hospital | Long Beach | California | 90801 | — |
| Children's Hospital Los Angeles | Los Angeles | California | 90027 | — |
| Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center | Los Angeles | California | 90048-1865 | — |
| Children's Hospital Central California | Madera | California | 93638-8762 | — |
| Children's Hospital and Research Center - Oakland | Oakland | California | 94609-1809 | — |
| Children's Hospital of Orange County | Orange | California | 92668 | — |
| University of California Davis Cancer Center | Sacramento | California | 95817 | — |
| Sutter Cancer Center | Sacramento | California | 95819 | — |
| Kaiser Permanente Medical Center - Oakland | Sacramento | California | 95825 | — |
| Children's Hospital and Health Center - San Diego | San Diego | California | 92123-4282 | — |
| Children's Hospital Cancer Center | Denver | Colorado | 80218-1088 | — |
| Carole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health Center | Hartford | Connecticut | 06106 | — |
| Alfred I. duPont Hospital for Children | Wilmington | Delaware | 19899 | — |
| Lombardi Cancer Center at Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007-2197 | — |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010-2970 | — |
| Broward General Medical Center Cancer Center | Fort Lauderdale | Florida | 33316 | — |
| Lee Cancer Care of Lee Memorial Health System | Fort Myers | Florida | 33908 | — |
| University of Florida Shands Cancer Center | Gainesville | Florida | 32610 | — |
| Memorial Cancer Institute at Memorial Regional Hospital | Hollywood | Florida | 33021 | — |
| Nemours Children's Clinic | Jacksonville | Florida | 32207 | — |
| University of Miami Sylvester Comprehensive Cancer Center | Miami | Florida | 33101 | — |
| Miami Children's Hospital | Miami | Florida | 33155 | — |
| Baptist-South Miami Regional Cancer Program | Miami | Florida | 33176 | — |
| Florida Hospital Cancer Institute at Florida Hospital Orlando | Orlando | Florida | 32804 | — |
| M.D. Anderson Cancer Center - Orlando | Orlando | Florida | 32806 | — |
| Sacred Heart Cancer Center at Sacred Heart Hospital | Pensacola | Florida | 32504 | — |
| All Children's Hospital | St. Petersburg | Florida | 33701 | — |
| St. Joseph's Cancer Institute at St. Joseph's Hospital | Tampa | Florida | 33607 | — |
| Kaplan Cancer Center at St. Mary's Medical Center | West Palm Beach | Florida | 33407 | — |
| Emory University Hospital - Atlanta | Atlanta | Georgia | 30322 | — |
| Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center | Savannah | Georgia | 31404-6283 | — |
| Cancer Research Center of Hawaii | Honolulu | Hawaii | 95813 | — |
| St. Luke's Mountain States Tumor Institute - Boise | Boise | Idaho | 83712-6297 | — |
| Children's Memorial Hospital - Chicago | Chicago | Illinois | 60614 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637-1463 | — |
| Lutheran General Cancer Care Center | Park Ridge | Illinois | 60068-1174 | — |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62794-9230 | — |
| Indiana University Cancer Center | Indianapolis | Indiana | 46202-5225 | — |
| St. Vincent Indianapolis Hospital | Indianapolis | Indiana | 46260 | — |
| Holden Comprehensive Cancer Center at University of Iowa | Iowa City | Iowa | 52242-1083 | — |
| Via Christi Cancer Center at Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| Wesley Medical Center | Wichita | Kansas | 67214 | — |
| Markey Cancer Center at University of Kentucky Chandler Medical Center | Lexington | Kentucky | 40506 | — |
| Kosair Children's Hospital | Louisville | Kentucky | 40202-1822 | — |
| CancerCare of Maine at Eastern Maine Medial Center | Bangor | Maine | 04401 | — |
| Maine Children's Cancer Program | Scarborough | Maine | 04074-9308 | — |
| Alvin and Lois Lapidus Cancer Institute at Sinai Hospital | Baltimore | Maryland | 21215 | — |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | 21287-5001 | — |
| Floating Hospital for Children | Boston | Massachusetts | 02111 | — |
| C.S. Mott Children's Hospital at University of Michigan | Ann Arbor | Michigan | 48109-0238 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Breslin Cancer Center at Ingham Regional Medical Center | East Lansing | Michigan | 48824-1313 | — |
| Spectrum Health Cancer Care - Butterworth Campus | Grand Rapids | Michigan | 49503-2560 | — |
| Van Elslander Cancer Center at St. John Hospital and Medical Center | Grosse Point Woods | Michigan | 48236 | — |
| CCOP - Kalamazoo | Kalamazoo | Michigan | 49007-5341 | — |
| Children's Hospitals and Clinics - Minneapolis/St. Paul | Minneapolis | Minnesota | 55404 | — |
| Fairview University Medical Center - University Campus | Minneapolis | Minnesota | 55455-0392 | — |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905-0001 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216-4505 | — |
| Keesler Medical Center - Keesler Air Force Base | Keesler Air Force Base | Mississippi | 39534-2511 | — |
| Children's Mercy Hospital | Kansas City | Missouri | 64108 | — |
| Cardinal Glennon Children's Hospital | St Louis | Missouri | 63104 | — |
| Siteman Cancer Center at Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| Children's Hospital of Omaha | Omaha | Nebraska | 68114-4113 | — |
| Sunrise Hospital and Medical Center | Las Vegas | Nevada | 89109-2306 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| St. Barnabas Medical Center | Livingston | New Jersey | 07039 | — |
| Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School | New Brunswick | New Jersey | 08901 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112-2094 | — |
| St. Joseph's Hospital and Medical Center | Paterson | New Jersey | 07503 | — |
| University of New Mexico Cancer Research and Treatment Center | Albuquerque | New Mexico | 87131-0001 | — |
| Brooklyn Hospital Center | Brooklyn | New York | 11201-5493 | — |
| Maimonides Medical Center | Brooklyn | New York | 11219 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Winthrop University Hospital | Mineola | New York | 11501 | — |
| Schneider Children's Hospital | New Hyde Park | New York | 11040 | — |
| Herbert Irving Comprehensive Cancer Center at Columbia University | New York | New York | 10032-1537 | — |
| SUNY Upstate Medical University Hospital | Syracuse | New York | 13210 | — |
| Albert Einstein Cancer Center at Albert Einstein College of Medicine | The Bronx | New York | 10467 | — |
| New York Medical College | Valhalla | New York | 10595 | — |
| Mission Hospitals - Memorial Campus | Asheville | North Carolina | 28801-4690 | — |
| Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill | Chapel Hill | North Carolina | 27599-7220 | — |
| Blumenthal Cancer Center at Carolinas Medical Center | Charlotte | North Carolina | 28232 | — |
| Presbyterian Cancer Center at Presbyterian Hospital | Charlotte | North Carolina | 28233 | — |
| Leo W. Jenkins Cancer Center at Pitt County Memorial Hospital | Greenville | North Carolina | 27834 | — |
| Comprehensive Cancer Center at Wake Forest University | Winston-Salem | North Carolina | 27157-1081 | — |
| CCOP - MeritCare Hospital | Fargo | North Dakota | 58122 | — |
| Children's Hospital Medical Center of Akron | Akron | Ohio | 44308-1062 | — |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229-3039 | — |
| Rainbow Babies and Children's Hospital | Cleveland | Ohio | 44106-5000 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195-5217 | — |
| Columbus Children's Hospital | Columbus | Ohio | 43205-2696 | — |
| Children's Medical Center - Dayton | Dayton | Ohio | 45404-1815 | — |
| Toledo Hospital | Toledo | Ohio | 43606 | — |
| Medical College of Ohio Cancer Institute | Toledo | Ohio | 43608 | — |
| Oklahoma University Medical Center | Oklahoma City | Oklahoma | 73104 | — |
| Cancer Institute at Oregon Health and Science University | Portland | Oregon | 97201-3098 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822-1320 | — |
| Penn State Cancer Institute at Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104-9786 | — |
| St. Christopher's Hospital for Children | Philadelphia | Pennsylvania | 19134 | — |
| Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15213-2583 | — |
| Hollings Cancer Center at Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Palmetto Health South Carolina Cancer Center | Columbia | South Carolina | 29203-6897 | — |
| Sioux Valley Hospital and University of South Dakota Medical Center | Sioux Falls | South Dakota | 57117-5039 | — |
| Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | 37232-6310 | — |
| Texas Tech University Health Sciences Center School of Medicine | Amarillo | Texas | 79106 | — |
| Children's Hospital of Austin | Austin | Texas | 78701 | — |
| Driscoll Children's Hospital | Corpus Christi | Texas | 78411-1721 | — |
| Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas | Dallas | Texas | 75390-9063 | — |
| Covenant Children's Hospital | Lubbock | Texas | 79410 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78207 | — |
| Methodist Children's Hospital of South Texas | San Antonio | Texas | 78229-3993 | — |
| CCOP - Scott and White Hospital | Temple | Texas | 76508 | — |
| Primary Children's Medical Center | Salt Lake City | Utah | 84113-1100 | — |
| Fletcher Allen Health Care - University Health Center Campus | Burlington | Vermont | 05405 | — |
| INOVA Fairfax Hospital | Fairfax | Virginia | 22031 | — |
| Massey Cancer Center at Virginia Commonwealth University | Richmond | Virginia | 23298-0121 | — |
| Carilion Cancer Center of Western Virginia | Roanoke | Virginia | 24029 | — |
| Children's Hospital and Regional Medical Center - Seattle | Seattle | Washington | 98105 | — |
| Providence Cancer Center at Sacred Heart Medical Center | Spokane | Washington | 99220-2555 | — |
| Mary Bridge Children's Hospital and Health Center - Tacoma | Tacoma | Washington | 98405 | — |
| Madigan Army Medical Center | Tacoma | Washington | 98431 | — |
| West Virginia University - Robert C. Byrd Health Sciences Center - Charleston Division | Charleston | West Virginia | 25302 | — |
| Cabell Huntington Hospital | Huntington | West Virginia | 25701 | — |
| St. Vincent Hospital | Green Bay | Wisconsin | 54301 | — |
| Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center | La Crosse | Wisconsin | 54601-5429 | — |
| University of Wisconsin Comprehensive Cancer Center | Madison | Wisconsin | 53792-0001 | — |
| Midwest Children's Cancer Center | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00070174, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 20, 2014 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00070174 live on ClinicalTrials.gov.