ClinicalTrials.gov record
Carboplatin and Gemcitabine Combined With Celecoxib and/or Zileuton in Treating Patients With Advanced Non-Small Cell Lung Cancer
ClinicalTrials.gov ID: NCT00070486
Public ClinicalTrials.gov record NCT00070486. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized Phase II Study of Eicosanoid Pathway Modulators and Cytotoxic Chemotherapy in Advanced Non-Small Cell Lung Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy, such as carboplatin and gemcitabine, work in different ways to stop tumor cells from dividing so they stop growing or die. Celecoxib and zileuton may stop the growth of tumor cells by stopping blood flow to the tumor and may block the enzymes necessary for tumor cell growth. Combining chemotherapy with celecoxib and/or zileuton may kill more tumor cells. PURPOSE: Randomized phase II trial to study the effectiveness of combining celecoxib and/or zileuton with carboplatin and gemcitabine in treating patients who have advanced non-small cell lung cancer.
Study identification
- NCT ID
- NCT00070486
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 140 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 120 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 30, 2003
- Primary completion
- Nov 30, 2006
- Completion
- Apr 30, 2011
- Last update posted
- Jun 29, 2016
2003 – 2011
United States locations
- U.S. sites
- 75
- U.S. states
- 28
- U.S. cities
- 58
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Northeast Alabama Regional Medical Center | Anniston | Alabama | 36207 | — |
| Rebecca and John Moores UCSD Cancer Center | La Jolla | California | 92093-0658 | — |
| Cedars-Sinai Comprehensive Cancer Center at Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| Naval Medical Center - San Diego | San Diego | California | 92134-3202 | — |
| Veterans Affairs Medical Center - San Diego | San Diego | California | 92161 | — |
| UCSF Comprehensive Cancer Center | San Francisco | California | 94115 | — |
| Veterans Affairs Medical Center - San Francisco | San Francisco | California | 94121 | — |
| CCOP - Christiana Care Health Services | Newark | Delaware | 19713 | — |
| Lombardi Cancer Center at Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| Walter Reed Army Medical Center | Washington D.C. | District of Columbia | 20307-5001 | — |
| Veterans Affairs Medical Center - Washington, DC | Washington D.C. | District of Columbia | 20422 | — |
| Broward General Medical Center | Fort Lauderdale | Florida | 33316 | — |
| Memorial Regional Cancer Center at Memorial Regional Hospital | Hollywood | Florida | 33021 | — |
| CCOP - Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| Palm Beach Cancer Institute | West Palm Beach | Florida | 33401 | — |
| MBCCOP - University of Illinois at Chicago | Chicago | Illinois | 60612 | — |
| Veterans Affairs Medical Center - Chicago (Westside Hospital) | Chicago | Illinois | 60612 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637-1470 | — |
| Louis A. Weiss Memorial Hospital | Chicago | Illinois | 60640 | — |
| CCOP - Evanston | Evanston | Illinois | 60201 | — |
| CCOP - Illinois Oncology Research Association | Peoria | Illinois | 61602 | — |
| West Suburban Center for Cancer Care | River Forest | Illinois | 60305 | — |
| Fort Wayne Medical Oncology and Hematology, Incorporated | Fort Wayne | Indiana | 46885-5099 | — |
| CCOP - Northern Indiana CR Consortium | South Bend | Indiana | 46601 | — |
| Holden Comprehensive Cancer Center at University of Iowa | Iowa City | Iowa | 52242-1009 | — |
| Baptist Hospital East - Louisville | Louisville | Kentucky | 40207 | — |
| Greenebaum Cancer Center at University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| University of Massachusetts Memorial Medical Center - University Campus | Worcester | Massachusetts | 01655 | — |
| Lakeland Cancer Care Center at Lakeland Hospital - St. Joseph | Saint Joseph | Michigan | 49085 | — |
| Veterans Affairs Medical Center - Minneapolis | Minneapolis | Minnesota | 55417 | — |
| University of Minnesota Cancer Center | Minneapolis | Minnesota | 55455 | — |
| Veterans Affairs Medical Center - Columbia (Truman Memorial) | Columbia | Missouri | 65201 | — |
| Ellis Fischel Cancer Center at University of Missouri - Columbia | Columbia | Missouri | 65203 | — |
| CCOP - Kansas City | Kansas City | Missouri | 64131 | — |
| Siteman Cancer Center | St Louis | Missouri | 63110 | — |
| Missouri Baptist Cancer Center | St Louis | Missouri | 63131 | — |
| UNMC Eppley Cancer Center at the University of Nebraska Medical Center | Omaha | Nebraska | 68198-7680 | — |
| CCOP - Southern Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | — |
| Veterans Affairs Medical Center - Las Vegas | Las Vegas | Nevada | 89106 | — |
| New Hampshire Oncology-Hematology, PA - Hooksett | Hooksett | New Hampshire | 03106 | — |
| Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756-0002 | — |
| Cooper University Hospital | Camden | New Jersey | 08103 | — |
| Veterans Affairs Medical Center - Buffalo | Buffalo | New York | 14215 | — |
| CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C. | East Syracuse | New York | 13057 | — |
| Queens Cancer Center of Queens Hospital | Jamaica | New York | 11432 | — |
| CCOP - North Shore University Hospital | Manhasset | New York | 11030 | — |
| North Shore University Hospital | Manhasset | New York | 11030 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10021 | — |
| New York Weill Cornell Cancer Center at Cornell University | New York | New York | 10021 | — |
| Mount Sinai Medical Center | New York | New York | 10029 | — |
| University Hospital at State University of New York - Upstate Medical University | Syracuse | New York | 13210 | — |
| Veterans Affairs Medical Center - Syracuse | Syracuse | New York | 13210 | — |
| Veterans Affairs Medical Center - Asheville | Asheville | North Carolina | 28805 | — |
| Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill | Chapel Hill | North Carolina | 27599-7295 | — |
| NorthEast Oncology Associates - Concord | Concord | North Carolina | 28025 | — |
| Veterans Affairs Medical Center - Durham | Durham | North Carolina | 27705 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| Cape Fear Valley Health System | Fayetteville | North Carolina | 28302-2000 | — |
| CCOP - Southeast Cancer Control Consortium | Goldsboro | North Carolina | 27534-9479 | — |
| FirstHealth Moore Regional Hospital | Pinehurst | North Carolina | 28374 | — |
| Zimmer Cancer Center at New Hanover Regional Medical Center | Wilmington | North Carolina | 28402-9025 | — |
| Comprehensive Cancer Center at Wake Forest University | Winston-Salem | North Carolina | 27157-1082 | — |
| Arthur G. James Cancer Hospital at Ohio State University | Columbus | Ohio | 43210-1240 | — |
| Oklahoma University Medical Center | Oklahoma City | Oklahoma | 73104 | — |
| Western Pennsylvania Hospital | Pittsburgh | Pennsylvania | 15224 | — |
| Lifespan: The Miriam Hospital | Providence | Rhode Island | 02906 | — |
| Veterans Affairs Medical Center - Dallas | Dallas | Texas | 75219 | — |
| Simmons Cancer Center at University of Texas Southwestern Medical Center - Dallas | Dallas | Texas | 75390-8852 | — |
| Vermont Cancer Center at University of Vermont | Burlington | Vermont | 05401-3498 | — |
| Martha Jefferson Hospital | Charlottesville | Virginia | 22902 | — |
| Virginia Oncology Associates - Norfolk | Norfolk | Virginia | 23502 | — |
| MBCCOP - Massey Cancer Center | Richmond | Virginia | 23298-0037 | — |
| Oncology and Hematology Associates of Southwest Virginia, Incorporated - Roanoke | Roanoke | Virginia | 24014 | — |
| St. Mary's Medical Center | Huntington | West Virginia | 25701 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
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About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00070486, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 29, 2016 · Synced Sep 3, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00070486 live on ClinicalTrials.gov.