"SALT Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia
Public ClinicalTrials.gov record NCT00072683. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Multicenter, Randomized, Double-blind, Placebo-controlled, Efficacy and Safety Study of the Effects of Titrated Oral Tolvaptan Tablets in Patients With Hyponatremia
Study identification
- NCT ID
- NCT00072683
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
- Industry
- Enrollment
- 205 participants
Conditions and interventions
Interventions
- tolvaptan Drug
- placebo matching tolvaptan Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 31, 2003
- Primary completion
- Nov 30, 2005
- Completion
- Nov 30, 2005
- Last update posted
- Jul 12, 2026
2003 – 2005
United States locations
- U.S. sites
- 23
- U.S. states
- 14
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| VA Greater Los Angeles Health Care Ctr | Los Angeles | California | 90073 | — |
| UCLA | Los Angeles | California | 93552 | — |
| UCSF Medical Center | San Francisco | California | 94143 | — |
| Aurora Denver Cardiology Association | Denver | Colorado | 80218 | — |
| University of Colorado Health Science Center | Denver | Colorado | 80262 | — |
| University of Florida Gainesville | Gainesville | Florida | 32610 | — |
| Charlotte Heart Group Research Ctr | Port Charlotte | Florida | 33952 | — |
| Medical College of Georgia | Augusta | Georgia | 30912 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| University of Iowa Hospital | Iowa City | Iowa | 52242 | — |
| Minneapolis VA Medical Center | Minneapolis | Minnesota | 55417 | — |
| Washington University Ctr for Clinical Studies | St Louis | Missouri | 63110 | — |
| Mercury Street Medical | Butte | Montana | 59701 | — |
| Northshore University Hospital | Great Neck | New York | — | — |
| Not listed | New York | New York | 10010 | — |
| University of North Carolina, Div. of Cardiology | Chapel Hill | North Carolina | 27599 | — |
| University Hospitals of Cleveland | Cleveland | Ohio | 44106 | — |
| Ohio State University Medical Center | Columbus | Ohio | 43210 | — |
| The Arthur P. Noyes Research Foundation | Norristown | Pennsylvania | 19401 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Baptist Clinical Research Ctr | Memphis | Tennessee | 38120 | — |
| Tennessee Center for Clinical Trials | Tullahoma | Tennessee | 37388 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00072683, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 12, 2026 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00072683 live on ClinicalTrials.gov.