Study Comparing Lapatinib (GW572016) And Letrozole Versus Letrozole In Subjects With Advanced Or Metastatic Breast Cancer
Public ClinicalTrials.gov record NCT00073528. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase III Study Comparing GW572016 and Letrozole Versus Letrozole in Subjects With Estrogen/Progesterone Receptor- Positive Advanced or Metastatic Breast Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study evaluated and compared the efficacy and tolerability of lapatinib and letrozole, with letrozole and placebo in post-menopausal women with hormone receptor positive (ER positive and/or PgR positive) advanced or metastatic breast cancer, who had not received prior therapy for advanced or metastatic disease.
Study identification
- NCT ID
- NCT00073528
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,286 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 9, 2003 (Actual)
- Primary completion
- Jun 3, 2008 (Actual)
- Completion
- Mar 22, 2018 (Actual)
- Last update posted
- Feb 24, 2021
2003 – 2018
United States locations
- U.S. sites
- 84
- U.S. states
- 32
- U.S. cities
- 81
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Novartis Investigative Site | Tucson | Arizona | 85715 | — |
| Novartis Investigative Site | Hot Springs | Arkansas | 71913 | — |
| Novartis Investigative Site | Jonesboro | Arkansas | 72401 | — |
| Novartis Investigative Site | Alhambra | California | 91801 | — |
| Novartis Investigative Site | Bakersfield | California | 93309 | — |
| Novartis Investigative Site | Duarte | California | 91010 | — |
| Novartis Investigative Site | Fountain Valley | California | 92708 | — |
| Novartis Investigative Site | Fresno | California | 93710 | — |
| Novartis Investigative Site | Fullerton | California | 92835 | — |
| Novartis Investigative Site | La Jolla | California | 92093-0987 | — |
| Novartis Investigative Site | Long Beach | California | 90813 | — |
| Novartis Investigative Site | Los Angeles | California | 90095 | — |
| Novartis Investigative Site | Montebello | California | 90640 | — |
| Novartis Investigative Site | Northridge | California | 91325 | — |
| Novartis Investigative Site | Oxnard | California | 93030 | — |
| Novartis Investigative Site | Pleasant Hill | California | 94523 | — |
| Novartis Investigative Site | Porterville | California | 93257 | — |
| Novartis Investigative Site | Redondo Beach | California | 90277 | — |
| Novartis Investigative Site | San Diego | California | 92120 | — |
| Novartis Investigative Site | Santa Barbara | California | 93105 | — |
| Novartis Investigative Site | Santa Maria | California | 93454 | — |
| Novartis Investigative Site | Vallejo | California | 94589 | — |
| Novartis Investigative Site | Vista | California | 92081 | — |
| Novartis Investigative Site | Aurora | Colorado | 80045 | — |
| Novartis Investigative Site | Denver | Colorado | 80220 | — |
| Novartis Investigative Site | Longmont | Colorado | 80501 | — |
| Novartis Investigative Site | Wheat Ridge | Colorado | 80033 | — |
| Novartis Investigative Site | New Haven | Connecticut | 06520 | — |
| Novartis Investigative Site | Boca Raton | Florida | 33428 | — |
| Novartis Investigative Site | Boca Raton | Florida | 33486 | — |
| Novartis Investigative Site | Gainesville | Florida | 32605 | — |
| Novartis Investigative Site | Gainesville | Florida | 32610 | — |
| Novartis Investigative Site | Hollywood | Florida | 33021 | — |
| Novartis Investigative Site | Lakeland | Florida | 33805 | — |
| Novartis Investigative Site | Miami | Florida | 33136 | — |
| Novartis Investigative Site | Orlando | Florida | 32804 | — |
| Novartis Investigative Site | Port Saint Lucie | Florida | 34952 | — |
| Novartis Investigative Site | West Palm Beach | Florida | 33401 | — |
| Novartis Investigative Site | Atlanta | Georgia | 30341 | — |
| Novartis Investigative Site | Marietta | Georgia | 30060 | — |
| Novartis Investigative Site | Savannah | Georgia | 31406 | — |
| Novartis Investigative Site | Peoria | Illinois | 61615 | — |
| Novartis Investigative Site | Skokie | Illinois | 60076 | — |
| Novartis Investigative Site | Indianapolis | Indiana | 46202 | — |
| Novartis Investigative Site | Bettendorf | Iowa | 52722 | — |
| Novartis Investigative Site | Louisville | Kentucky | 40202 | — |
| Novartis Investigative Site | Metairie | Louisiana | 70006 | — |
| Novartis Investigative Site | New Orleans | Louisiana | 70121 | — |
| Novartis Investigative Site | Worcester | Massachusetts | 01608 | — |
| Novartis Investigative Site | Duluth | Minnesota | 55805 | — |
| Novartis Investigative Site | Minneapolis | Minnesota | 55407-3799 | — |
| Novartis Investigative Site | Robbinsdale | Minnesota | 55422 | — |
| Novartis Investigative Site | Saint Louis Park | Minnesota | 55426 | — |
| Novartis Investigative Site | Saint Charles | Missouri | 63304 | — |
| Novartis Investigative Site | St Louis | Missouri | 63141 | — |
| Novartis Investigative Site | Omaha | Nebraska | 68114 | — |
| Novartis Investigative Site | Las Vegas | Nevada | 89169 | — |
| Novartis Investigative Site | Voorhees Township | New Jersey | 08043 | — |
| Novartis Investigative Site | Santa Fe | New Mexico | 87505 | — |
| Novartis Investigative Site | Manhasset | New York | 11030 | — |
| Novartis Investigative Site | Rochester | New York | 14623 | — |
| Novartis Investigative Site | Chapel Hill | North Carolina | 27599-7305 | — |
| Novartis Investigative Site | Greenville | North Carolina | 27834 | — |
| Novartis Investigative Site | Fargo | North Dakota | 58103 | — |
| Novartis Investigative Site | Canton | Ohio | 44718 | — |
| Novartis Investigative Site | Hershey | Pennsylvania | 17033 | — |
| Novartis Investigative Site | Philadelphia | Pennsylvania | 19111 | — |
| Novartis Investigative Site | Pittsburgh | Pennsylvania | 15212 | — |
| Novartis Investigative Site | West Columbia | South Carolina | 29210 | — |
| Novartis Investigative Site | Germantown | Tennessee | 38138 | — |
| Novartis Investigative Site | Knoxville | Tennessee | 37916 | — |
| Novartis Investigative Site | Amarillo | Texas | 79106 | — |
| Novartis Investigative Site | Dallas | Texas | 75246 | — |
| Novartis Investigative Site | Dallas | Texas | 75390-9113 | — |
| Novartis Investigative Site | Houston | Texas | 77025 | — |
| Novartis Investigative Site | Irving | Texas | 75061 | — |
| Novartis Investigative Site | Ogden | Utah | 84403 | — |
| Novartis Investigative Site | Salt Lake City | Utah | 84106 | — |
| Novartis Investigative Site | Burlington | Vermont | 05401 | — |
| Novartis Investigative Site | Danville | Virginia | 24541 | — |
| Novartis Investigative Site | Richmond | Virginia | 23230 | — |
| Novartis Investigative Site | Seattle | Washington | 98104 | — |
| Novartis Investigative Site | Tacoma | Washington | 98405 | — |
| Novartis Investigative Site | Charleston | West Virginia | 25304 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 194 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00073528, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 24, 2021 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00073528 live on ClinicalTrials.gov.