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Completed Phase 2 Interventional Results available

Pentostatin in Treating Patients With Refractory Chronic Graft-Versus-Host Disease

ClinicalTrials.gov ID: NCT00074035

Public ClinicalTrials.gov record NCT00074035. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 24, 2026, 3:10 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Trial Of Intravenous Pentostatin For The Treatment Of Patients With Refractory Chronic Graft-Versus-Host Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Pentostatin may be effective in treating chronic graft-versus-host disease by stopping the immune system from rejecting donor stem cells or donor white blood cells. PURPOSE: This phase II trial is studying how well pentostatin works in treating patients with chronic graft-versus-host disease that is refractory (not responsive) to treatment with steroids.

Study identification

NCT ID
NCT00074035
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
39 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2003
Primary completion
Jul 31, 2008
Completion
Oct 31, 2014
Last update posted
Nov 2, 2021

2003 – 2014

United States locations

U.S. sites
16
U.S. states
10
U.S. cities
14
Facility City State ZIP Site status
Tunnell Cancer Center at Beebe Medical Center Lewes Delaware 19958
CCOP - Christiana Care Health Services Newark Delaware 19713
University of Illinois Cancer Center Chicago Illinois 60612-7243
University of Chicago Cancer Research Center Chicago Illinois 60637-1470
Greenebaum Cancer Center at University of Maryland Medical Center Baltimore Maryland 21201
Union Hospital Cancer Program at Union Hospital Elkton Maryland 21921
Mayo Clinic Cancer Center Rochester Minnesota 55905
Cancer Institute of New Jersey at Cooper - Voorhees Voorhees Township New Jersey 08043
New York Weill Cornell Cancer Center at Cornell University New York New York 10021
Duke Comprehensive Cancer Center Durham North Carolina 27710
Wake Forest University Comprehensive Cancer Center Winston-Salem North Carolina 27157-1096
Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center Columbus Ohio 43210-1240
Abramson Cancer Center of the University of Pennsylvania Philadelphia Pennsylvania 19104-4283
Fox Chase Cancer Center - Philadelphia Philadelphia Pennsylvania 19111-2497
Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital Pittsburgh Pennsylvania 15224-1791
Virginia Commonwealth University Massey Cancer Center Richmond Virginia 23298-0037

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00074035, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 2, 2021 · Synced Sep 24, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00074035 live on ClinicalTrials.gov.

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