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Completed Phase 3 Interventional

The PRECISE Trial: Study of IL13-PE38QQR Compared to GLIADEL Wafer in Patients With Recurrent Glioblastoma Multiforme

ClinicalTrials.gov ID: NCT00076986

Public ClinicalTrials.gov record NCT00076986. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 12:45 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

PRECISE - Phase III Randomized Evaluation of Convection Enhanced Delivery of IL13-PE38QQR Compared to GLIADEL® Wafer With Survival Endpoint in Glioblastoma Multiforme Patients at First Recurrence

Study identification

NCT ID
NCT00076986
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
INSYS Therapeutics Inc
Industry
Enrollment
300 participants

Conditions and interventions

Interventions

  • IL13-PE38QQR Drug
  • surgery and catheter placement (2 procedures) Procedure
  • prolifespan 20 with carmustine implant (GLIADEL® Wafer) Drug
  • surgery and wafer placement (1 procedure) Procedure

Drug · Procedure

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 31, 2004
Primary completion
Feb 28, 2007
Completion
Feb 28, 2007
Last update posted
Jun 5, 2011

2004 – 2007

United States locations

U.S. sites
40
U.S. states
25
U.S. cities
33
Facility City State ZIP Site status
University of Alabama at Birmingham - Division of Neurosurgery Birmingham Alabama 35294-3410
City of Hope National Medical Center Duarte California 91010-3000
Los Angeles County/USC Los Angeles California 90033
Cedars-Sinai Medical Center - Neurological Institute Los Angeles California 90048
University of California - Los Angeles Neuro-Oncology Program Los Angeles California 90095-1769
University of California San Francisco - Dept. of Neurological Surgery San Francisco California 94143
University of Colorado Hospital - Anschutz Cancer Pavillion Aurora Colorado 80010
Yale University School of Medicine - Department of Neurosurgery New Haven Connecticut 06520
Florida Hospital Neuroscience Institute Orlando Florida 32804
H. Lee Moffitt Cancer Center and Research Institute Tampa Florida 33612
Emory University Atlanta Georgia 30322
Northwestern Medical Faculty Foundation, Inc. - Dept of Neurological Surgery Chicago Illinois 60611
CINN at Rush Unversity Medical School Chicago Illinois 60612
University of Chicago Medical Center Chicago Illinois 60637
Evanston Northwestern Healthcare Evanston Illinois 60201-1782
The Johns Hopkins University Baltimore Maryland 21287
Dana Farber Cancer Institute Boston Massachusetts 02115
Henry Ford Health Systems Detroit Michigan 48202
Mayo Clinic Rochester Minnesota 55905
St. Louis University St Louis Missouri 63104
Memorial Sloan Kettering Cancer Center Department of Neurology New York New York 10021
Weill Cornell Medical College - Department of Neurological Surgery New York New York 10021
Columbia University Medical Center - Neurological Institute New York New York 10032
Carolina Neurosurgery & Spine Assoc. Charlotte North Carolina 28204
Duke University Medical Center Durham North Carolina 27710
Wake Forest University Health Sciences - Department of Neurosurgery Winston-Salem North Carolina 27157
Cleveland Clinic Foundation Department of Neurological Surgery Cleveland Ohio 44195
The Ohio State University Medical Center Columbus Ohio 43210
Oregon Health & Science University Portland Oregon 97239
The Hospital of the University of Pennsylvania Philadelphia Pennsylvania 19104
Medical University of South Carolina Charleston South Carolina 29425
Baptist Memorial Hospital Memphis Tennessee 38120
UT Southwestern Medical Center Dallas Texas 75390
Baylor College of Medicine Houston Texas 77030
University of Texas M.D. Anderson Cancer Center Houston Texas 77030
Huntsman Cancer Insitute Salt Lake City Utah 84132
University of Virginia Health Systems - Department of Neurological Surgery Charlottesville Virginia 22908
Benaroya Research Institute at Virginia Mason Medical Center Seattle Washington 98101
West Virginia University Department of Neurosurgery Morgantown West Virginia 26506
University of Wisconsin Hospital and Clinic Madison Wisconsin 53792

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00076986, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 5, 2011 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00076986 live on ClinicalTrials.gov.

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