The PRECISE Trial: Study of IL13-PE38QQR Compared to GLIADEL Wafer in Patients With Recurrent Glioblastoma Multiforme
Public ClinicalTrials.gov record NCT00076986. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
PRECISE - Phase III Randomized Evaluation of Convection Enhanced Delivery of IL13-PE38QQR Compared to GLIADEL® Wafer With Survival Endpoint in Glioblastoma Multiforme Patients at First Recurrence
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the PRECISE trial is to determine whether overall survival duration, safety, and quality of life are improved for patients treated with IL13-PE38QQR compared to patients treated with GLIADEL® Wafer following surgical tumor removal in the treatment of first recurrence of glioblastoma multiforme.
Study identification
- NCT ID
- NCT00076986
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 300 participants
Conditions and interventions
Conditions
Interventions
- IL13-PE38QQR Drug
- surgery and catheter placement (2 procedures) Procedure
- prolifespan 20 with carmustine implant (GLIADEL® Wafer) Drug
- surgery and wafer placement (1 procedure) Procedure
Drug · Procedure
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 2004 (Type not available)
- Primary completion
- Mar 2007 (Actual)
- Completion
- Mar 2007 (Actual)
- Last update posted
- Jun 6, 2011
2004 – 2007
United States locations
- U.S. sites
- 40
- U.S. states
- 25
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham - Division of Neurosurgery | Birmingham | Alabama | 35294-3410 | — |
| City of Hope National Medical Center | Duarte | California | 91010-3000 | — |
| Los Angeles County/USC | Los Angeles | California | 90033 | — |
| Cedars-Sinai Medical Center - Neurological Institute | Los Angeles | California | 90048 | — |
| University of California - Los Angeles Neuro-Oncology Program | Los Angeles | California | 90095-1769 | — |
| University of California San Francisco - Dept. of Neurological Surgery | San Francisco | California | 94143 | — |
| University of Colorado Hospital - Anschutz Cancer Pavillion | Aurora | Colorado | 80010 | — |
| Yale University School of Medicine - Department of Neurosurgery | New Haven | Connecticut | 06520 | — |
| Florida Hospital Neuroscience Institute | Orlando | Florida | 32804 | — |
| H. Lee Moffitt Cancer Center and Research Institute | Tampa | Florida | 33612 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Northwestern Medical Faculty Foundation, Inc. - Dept of Neurological Surgery | Chicago | Illinois | 60611 | — |
| CINN at Rush Unversity Medical School | Chicago | Illinois | 60612 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Evanston Northwestern Healthcare | Evanston | Illinois | 60201-1782 | — |
| The Johns Hopkins University | Baltimore | Maryland | 21287 | — |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Henry Ford Health Systems | Detroit | Michigan | 48202 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| St. Louis University | St Louis | Missouri | 63104 | — |
| Memorial Sloan Kettering Cancer Center Department of Neurology | New York | New York | 10021 | — |
| Weill Cornell Medical College - Department of Neurological Surgery | New York | New York | 10021 | — |
| Columbia University Medical Center - Neurological Institute | New York | New York | 10032 | — |
| Carolina Neurosurgery & Spine Assoc. | Charlotte | North Carolina | 28204 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Wake Forest University Health Sciences - Department of Neurosurgery | Winston-Salem | North Carolina | 27157 | — |
| Cleveland Clinic Foundation Department of Neurological Surgery | Cleveland | Ohio | 44195 | — |
| The Ohio State University Medical Center | Columbus | Ohio | 43210 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| The Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Baptist Memorial Hospital | Memphis | Tennessee | 38120 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| University of Texas M.D. Anderson Cancer Center | Houston | Texas | 77030 | — |
| Huntsman Cancer Insitute | Salt Lake City | Utah | 84132 | — |
| University of Virginia Health Systems - Department of Neurological Surgery | Charlottesville | Virginia | 22908 | — |
| Benaroya Research Institute at Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| West Virginia University Department of Neurosurgery | Morgantown | West Virginia | 26506 | — |
| University of Wisconsin Hospital and Clinic | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00076986, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 6, 2011 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00076986 live on ClinicalTrials.gov.