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Terminated Phase 2 Interventional Results available

Captopril in Treating Patients With Non-Small Cell Lung Cancer or Limited-Stage Small Cell Lung Cancer That Has Been Previously Treated With Radiation Therapy With or Without Chemotherapy

ClinicalTrials.gov ID: NCT00077064

Public ClinicalTrials.gov record NCT00077064. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 22, 2026, 5:12 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Randomized Trial With Captopril In Patients Who Have Received Radiation Therapy +/- Chemotherapy For Stage II-IIIB Non-Small Cell Lung Cancer, Stage I Central Non-Small Cell Lung Cancer, Or Limited-Stage Small-Cell Lung Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Captopril is a drug that may be able to decrease side effects caused by radiation therapy, and may improve the quality of life of patients with non-small cell lung cancer or limited-stage small cell lung cancer. PURPOSE: This randomized phase II trial is studying how well captopril works in decreasing side effects and improving the quality of life in patients who have received radiation therapy with or without chemotherapy for stage I, stage II, or stage IIIB non-small cell lung cancer or limited-stage small cell lung cancer.

Study identification

NCT ID
NCT00077064
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Enrollment
81 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 2003 (Type not available)
Primary completion
Nov 2008 (Actual)
Completion
Dec 2016 (Actual)
Last update posted
Mar 8, 2018

2003 – 2016

United States locations

U.S. sites
87
U.S. states
22
U.S. cities
65
Facility City State ZIP Site status
Lurleen Wallace Comprehensive Cancer at University of Alabama - Birmingham Birmingham Alabama 35294 —
Mobile Infirmary Medical Center Mobile Alabama 36652-2144 —
Arizona Oncology Services Foundation Phoenix Arizona 85013 —
Providence Saint Joseph Medical Center - Burbank Burbank California 91505 —
Veterans Affairs Medical Center - Long Beach Long Beach California 90822 —
Robert and Beverly Lewis Family Cancer Care Center at Pomona Valley Hospital Medical Center Pomona California 91767 —
General Robert Huyser Cancer Center at David Grant Medical Center Travis Air Force Base California 94535-1800 —
University of Colorado Cancer Center at UC Health Sciences Center Aurora Colorado 80045 —
University of Florida Shands Cancer Center Gainesville Florida 32610-0232 —
Baptist-South Miami Regional Cancer Program Miami Florida 33176 —
Saint Anthony's Hospital at Saint Anthony's Health Center Alton Illinois 62002 —
Good Samaritan Regional Health Center Mount Vernon Illinois 62864 —
Saint John's Cancer Center at Saint John's Medical Center Anderson Indiana 46016 —
Methodist Cancer Center at Methodist Hospital Indianapolis Indiana 46202 —
Cancer Treatment Center for Southern Kentucky Bowling Green Kentucky 42101 —
Central Baptist Hospital Lexington Kentucky 40503-9985 —
Central Maine Comprehensive Cancer Center at Central Maine Medical Center Lewiston Maine 04240 —
Greenebaum Cancer Center at University of Maryland Medical Center Baltimore Maryland 21201 —
Hickman Cancer Center at Bixby Medical Center Adrian Michigan 49221 —
Josephine Ford Cancer Center at Henry Ford Hospital Detroit Michigan 48202 —
Great Lakes Cancer Institute at McLaren Regional Medical Center Flint Michigan 48532 —
Borgess Medical Center Kalamazoo Michigan 49001 —
West Michigan Cancer Center Kalamazoo Michigan 49007-3731 —
Bronson Methodist Hospital Kalamazoo Michigan 49007 —
Haematology-Oncology Associates of Ohio and Michigan, PC Lambertville Michigan 48144 —
Community Cancer Center of Monroe Monroe Michigan 48162 —
Mercy Memorial Hospital - Monroe Monroe Michigan 48162 —
William Beaumont Hospital - Royal Oak Campus Royal Oak Michigan 48073 —
Regional Cancer Center at Singing River Hospital Pascagoula Mississippi 39581 —
Southeast Missouri Regional Cancer Center at Southeast Missouri Hospital Cape Girardeau Missouri 63701 —
Saint Francis Medical Center Cape Girardeau Missouri 63703 —
CCOP - St. Louis-Cape Girardeau St Louis Missouri 63141 —
David C. Pratt Cancer Center at St. John's Mercy St Louis Missouri 63141 —
Monmouth Medical Center Long Branch New Jersey 07740-6395 —
Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton Marlton New Jersey 08053 —
J. Phillip Citta Regional Cancer Center at Community Medical Center Toms River New Jersey 08755 —
SUNY Downstate Medical Center Brooklyn New York 11203 —
New York Methodist Hospital Brooklyn New York 11215 —
Fitzpatrick Cancer Center at Champlain Valley Physicians Hospital Medical Center Plattsburgh New York 12901 —
Highland Hospital of Rochester Rochester New York 14620 —
James P. Wilmot Cancer Center at University of Rochester Medical Center Rochester New York 14642 —
Mission Hospitals - Memorial Campus Asheville North Carolina 28801 —
Wayne Memorial Hospital, Incorporated Goldsboro North Carolina 27534 —
Wayne Radiation Oncology Goldsboro North Carolina 27534 —
Cancer Centers of North Carolina - Raleigh Raleigh North Carolina 27607 —
Rex Cancer Center at Rex Hospital Raleigh North Carolina 27607 —
Wilmed Radiation Oncology Services Wilson North Carolina 27893 —
Trinity CancerCare Center Minot North Dakota 58701 —
Wood County Oncology Center Bowling Green Ohio 43402 —
Adena Regional Medical Center Chillicothe Ohio 45601 —
Riverside Methodist Hospital Cancer Care Columbus Ohio 43214-3998 —
CCOP - Columbus Columbus Ohio 43215 —
Grant Medical Center Cancer Care Columbus Ohio 43215 —
Mount Carmel Health - West Hospital Columbus Ohio 43222 —
Doctors Hospital at Ohio Health Columbus Ohio 43228 —
Grady Memorial Hospital Delaware Ohio 43015 —
Fremont Memorial Hospital Fremont Ohio 43420 —
Fairfield Medical Center Lancaster Ohio 43130 —
Lima Memorial Hospital Lima Ohio 45804 —
Strecker Cancer Center at Marietta Memorial Hospital Marietta Ohio 45750 —
Northwest Ohio Oncology Center Maumee Ohio 43537 —
St. Luke's Hospital Maumee Ohio 43537 —
Licking Memorial Cancer Care Program at Licking Memorial Hospital Newark Ohio 43055 —
St. Charles Mercy Hospital Oregon Ohio 43616 —
Toledo Clinic - Oregon Oregon Ohio 43616 —
Firelands Regional Medical Center Sandusky Ohio 44870 —
North Coast Cancer Care, Incorporated Sandusky Ohio 44870 —
Mercy Medical Center Springfield Ohio 45504 —
Community Hospital of Springfield and Clark County Springfield Ohio 45505 —
Flower Hospital Cancer Center Sylvania Ohio 43560 —
Mercy Hospital of Tiffin Tiffin Ohio 44883 —
Toledo Hospital Toledo Ohio 43606 —
St. Vincent Mercy Medical Center Toledo Ohio 43608 —
Medical University of Ohio Cancer Center Toledo Ohio 43614 —
CCOP - Toledo Community Hospital Toledo Ohio 43617 —
Toledo Clinic, Incorporated - Main Clinic Toledo Ohio 43623 —
Fulton County Health Center Wauseon Ohio 43567 —
Mount Carmel St. Ann's Cancer Center Westerville Ohio 43081 —
Genesis - Good Samaritan Hospital Zanesville Ohio 43701 —
CCOP - Greenville Greenville South Carolina 29615 —
Rapid City Regional Hospital Rapid City South Dakota 57701 —
Fredericksburg Oncology, Incorporated Fredericksburg Virginia 22401 —
Columbia Saint Mary's Hospital - Ozaukee Mequon Wisconsin 53097 —
Columbia-Saint Mary's Cancer Care Center Milwaukee Wisconsin 53211 —
Vince Lombardi Cancer Clinic at Aurora St. Luke's Medical Center Milwaukee Wisconsin 53215 —
All Saints Cancer Center at Wheaton Franciscan Healthcare Racine Wisconsin 53405 —
West Allis Memorial Hospital West Allis Wisconsin 53227 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00077064, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 8, 2018 · Synced Oct 22, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00077064 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →