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Completed Phase 4 Interventional Results available

A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With COPEGUS (Ribavirin) in Interferon-Naive Patients With Chronic Hepatitis C Infection (CHC).

ClinicalTrials.gov ID: NCT00077649

Public ClinicalTrials.gov record NCT00077649. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 13, 2026, 4:49 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Randomized, Multicenter, Double-blind, Phase IV Pilot Study Evaluating the Effect of PEGASYS Doses of 180 ug or 270 ug in Combination With Copegus Doses of 1200 mg or 1600 mg on Viral Kinetics, Virological Response, Pharmacokinetics, and Safety in Interferon-naïve Patients With Chronic Hepatitis C Genotype 1 Virus Infection of High Viral Titer and Body Weight Greater Than 85 kg

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The effects of treatment with different doses of PEGASYS in combination with different doses of ribavirin will be evaluated in patients with CHC genotype 1 who have a high viral titer, body weight greater than 85kg (187lbs) and no prior treatment with interferon. The anticipated time on study treatment is 3-12 months and the target sample size is 100-500 individuals.

Study identification

NCT ID
NCT00077649
Recruitment status
Completed
Study type
Interventional
Phase
Phase 4
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
188 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 31, 2003
Primary completion
Nov 30, 2005
Completion
Nov 30, 2005
Last update posted
Apr 17, 2016

2004 – 2005

United States locations

U.S. sites
24
U.S. states
15
U.S. cities
23
Facility City State ZIP Site status
Not listed La Jolla California 92037-1030
Not listed Long Beach California 90822
Not listed San Diego California 92105
Not listed San Diego California 92154
Not listed Farmington Connecticut 06030
Not listed Bradenton Florida 34209
Not listed Gainesville Florida 32610-0214
Not listed Jacksonville Florida 32207
Not listed Wellington Florida 33414
Not listed Honolulu Hawaii 96817
Not listed Chicago Illinois 60612
Not listed Iowa City Iowa 52242
Not listed Boston Massachusetts 02111
Not listed St Louis Missouri 63104
Not listed Manhasset New York 11030
Not listed Chapel Hill North Carolina 27599-7584
Not listed Statesville North Carolina 28677
Not listed Cincinnati Ohio 45267-0595
Not listed Philadelphia Pennsylvania 19104
Not listed Pittsburgh Pennsylvania 15213
Not listed Houston Texas 77030
Not listed Salt Lake City Utah 84121
Not listed Charlottesville Virginia 22906-0013
Not listed Richmond Virginia 23249

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00077649, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 17, 2016 · Synced Sep 13, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00077649 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →