Study of CEP-701 (Lestaurtinib) in Patients With Acute Myeloid Leukemia (AML)
Public ClinicalTrials.gov record NCT00079482. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Open-Label Study of Oral CEP-701 Administered in Sequence With Standard Chemotherapy to Patients With Relapsed Acute Myeloid Leukemia (AML) Expressing FLT-3 Activating Mutations
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to determine whether CEP-701 given in sequence with induction chemotherapy increases the proportion of patients with relapsed acute myeloid leukemia (AML) who achieve a second complete remission (CR).
Study identification
- NCT ID
- NCT00079482
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 224 participants
Conditions and interventions
Conditions
Interventions
- CEP-701 Drug
- high-dose cytarabine Drug
- Mitozantrone, Etoposide, Cytarabine (combination Chemotherapy) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2003 (Type not available)
- Primary completion
- Mar 2009 (Actual)
- Completion
- Jan 2010 (Actual)
- Last update posted
- Jul 21, 2016
2003 – 2010
United States locations
- U.S. sites
- 34
- U.S. states
- 24
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama | Birmingham | Alabama | 35294 | — |
| Mayo-Scottsdale | Scottsdale | Arizona | 85259 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| USC/Norris Cancer Center | Los Angeles | California | 90033 | — |
| Stanford Medical Center | Stanford | California | 94305 | — |
| Moffitt Cancer Center | Tampa | Florida | 33606 | — |
| Emory University School of Medicine | Atlanta | Georgia | 30322 | — |
| ACORN-Central Georgia Hematology/Oncology | Macon | Georgia | 31201 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| St. Francis Cancer Care Services | Beech Grove | Indiana | 46107 | — |
| Indiana Cancer Pavillion | Indianapolis | Indiana | 46202 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| LSU Shreveport | Shreveport | Louisiana | 71103 | — |
| Univeristy of Maryland Medicine - Greenebaum Cancer Center | Baltimore | Maryland | 21201 | — |
| Johns Hopkins | Baltimore | Maryland | 21231 | — |
| Tufts New England Medical Center | Boston | Massachusetts | 02111 | — |
| Beth Israel Hospital | Boston | Massachusetts | 02215 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Karmanos Cancer Institute Wayne State University | Detroit | Michigan | 48201 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| The Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| University of Nebraska | Omaha | Nebraska | 68198 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| New York Presbyterian | New York | New York | 10021 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15232 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| ACORN-The West Clinic | Memphis | Tennessee | 38120 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 47 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00079482, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 21, 2016 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00079482 live on ClinicalTrials.gov.