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Completed Phase 3 Interventional

Whole Brain Radiation Therapy With Oxygen, With or Without RSR13, in Women With Brain Metastases From Breast Cancer

ClinicalTrials.gov ID: NCT00083304

Public ClinicalTrials.gov record NCT00083304. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 20, 2026, 1:08 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3 Randomized, Open-label Comparative Study of Standard Whole Brain Radiation Therapy With Supplemental Oxygen, With or Without Concurrent RSR13 (Efaproxiral), in Women With Brain Metastases From Breast Cancer

Study identification

NCT ID
NCT00083304
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Spectrum Pharmaceuticals, Inc
Industry
Enrollment
368 participants

Conditions and interventions

Interventions

  • Efaproxiral Drug
  • Whole Brain Radiation Therapy (WBRT) Radiation
  • Supplemental Oxygen Other

Drug · Radiation · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 31, 2004
Primary completion
May 31, 2007
Completion
May 31, 2007
Last update posted
May 9, 2013

2004 – 2007

United States locations

U.S. sites
39
U.S. states
21
U.S. cities
36
Facility City State ZIP Site status
Virginia G. Piper Cancer Center, Arizona Oncology Services Phoenix Arizona 85013
Arizona Cancer Center, University of Arizona Tucson Arizona 85724-5081
The University of Arkansas for Medical Sciences Little Rock Arkansas 72205
Alta Bates Comprehensive Cancer Center Berkeley California 94704
University of California at Los Angeles Los Angeles California 90095
Radiological Associates of Sacramento Sacramento California 95816
UCSF - Comprehensive Cancer Center San Francisco California 94115
Yale University School of Medicine New Haven Connecticut 06520
Boca Raton Community Hospital Boca Raton Florida 33486
University of Miami Medical Miami Florida 33136
University of South Florida - H. Lee Moffitt Cancer Center Tampa Florida 33612
Emory University Winship Cancer Institute Atlanta Georgia 30322
Northwestern University Chicago Illinois 60611
Parkview Research Center Fort Wayne Indiana 46805
Indiana University School of Medicine Indianapolis Indiana 46204
Siouxland Regional Cancer Center Sioux City Iowa 51101
Johns Hopkins Oncology Center Baltimore Maryland 21231
Maryland Hematology Oncology Baltimore Maryland 21236
Franklin Square Hospital Center Baltimore Maryland 21237
Center for Cancer and Blood Disorders Bethesda Maryland 20817
Beth Israel Deaconess Medical Center Boston Massachusetts 02215
Henry Ford Hospital Detroit Michigan 48202
University of Minnesota Cancer Center Minneapolis Minnesota 55455
Washington University School of Medicine St Louis Missouri 63110
Dent Neurologic Institute Amherst New York 14226
SUNY Downstate Medical Center Brooklyn New York 11203
Eastchester Center for Cancer Care The Bronx New York 10469
University of North Carolina Breast Center Chapel Hill North Carolina 27599
Duke University Medical Center Durham North Carolina 27710
University of Cincinnati Division of Hematology-Oncology Cincinnati Ohio 45267
Cleveland Clinic Hospital Cleveland Ohio 44195
Ohio State University Columbus Ohio 43210
Thomas Jefferson University Philadelphia Pennsylvania 19107
Fox Chase Cancer Center Philadelphia Pennsylvania 19111
Texas Oncology Dallas Texas 75230
Texas Oncology Fort Worth Texas 76104
Virginia Mason Cancer Center Seattle Washington 98101
Wenatchee Valley Clinic Wenatchee Washington 98801
University of Wisconsin Madison Wisconsin 53792

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 55 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00083304, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 9, 2013 · Synced Jul 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00083304 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →