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Completed Phase 3 Interventional Accepts healthy volunteers

Vaginal Progesterone to Reduce the Risk of Another Preterm Birth

ClinicalTrials.gov ID: NCT00086177

Public ClinicalTrials.gov record NCT00086177. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 7:14 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Randomized, Double-blind, Placebo-controlled, Multi-center Study to Assess the Efficacy, Safety, and Tolerability of 8% Progesterone Vaginal Gel in Preventing Preterm Delivery in Pregnant Women at Increased-Risk for Preterm Delivery

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This research study is being conducted at over 12 pregnancy research centers in the US. The study will compare an investigational treatment with a placebo (a treatment without medication). Neither the investigators nor the patients in the trial will know which treatment has been assigned. All study medications will be given vaginally once a day. Treatment will begin before pregnancy week 23 and will continue until the end of pregnancy week 36.

Study identification

NCT ID
NCT00086177
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Juniper Pharmaceuticals, Inc.
Industry
Enrollment
636 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 45 Years
Sex
Female
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2004
Primary completion
Dec 31, 2006
Completion
Feb 28, 2009
Last update posted
Aug 18, 2010

2004 – 2009

United States locations

U.S. sites
45
U.S. states
22
U.S. cities
42
Facility City State ZIP Site status
University of South Alabama Department of OBGYN Mobile Alabama 36604
Visions Clinical Research-Tucson Tucson Arizona 85712
Women's Health Department Colton California 92324
SanDiego Perinatal Center San Diego California 92123
Harbor - UCLA Medical Center Torrance California 90509
Kaiser Permanente Denver Colorado 80205
Northside Maternal Fetal Specialists Atlanta Georgia 30342
Memorial Health University Medical Center Savannah Georgia 31404
University of Illinois Chicago Illinois 60612
University of Chicago Chicago Illinois 60637
Central Baptist Hospital Lexington Kentucky 40503
Maternal Fetal Medicine Norton Suburban Hospital Louisville Kentucky 40207
Maternal Fetal Medicine &Woman's Health Research Baton Rouge Louisiana 70815
Louisiana State University Health Sciences Center-Shreveport Shreveport Louisiana 71103
Johns Hopkins Community Physicians Baltimore Maryland 21211
Holy Cross Hospital Silver Springs Maryland 20910
Brigham and Women's Hospital Boston Massachusetts 02115
St. Elizabeth's Medical Center -MFM Brighton Massachusetts 02135
St. Louis University St Louis Missouri 63021
Washington University St Louis Missouri 63110
Cooper University Hospital Camden New Jersey 08103
Department of OBGYN, St. Barnabas Medical Center Livingston New Jersey 07039
University of New Mexico Albuquerque New Mexico 87131
St. Luke's - Roosevelt Hospital New York New York 10019
Jacobi Medical Center The Bronx New York 10461
Montefiore Medical Center The Bronx New York 10461
Pitt County Memorial Hospital Greenville North Carolina 27834
Lyndhurst Gynecologic Associates Winston-Salem North Carolina 27103
Ohio Permanente Medical Group Bedford Ohio 44146
University of Cincinnati Cincinnati Ohio 45219
MacDonald Clinical Trials Unit, University Hospitals of Cleveland Cleveland Ohio 44104-5034
The Toledo Hospital Toledo Ohio 43606
Geisinger Medical Center Danville Pennsylvania 17822
Temple University Medical Center Philadelphia Pennsylvania 19140
Abington Primary Women's Healthcare Willow Grove Pennsylvania 19090
University Medical Group, Dept of OB/GYN Greenville South Carolina 29605
Regional Obstetrical Consultants Chattanooga Tennessee 37403
Gynecology & Obstetrics Memphis Tennessee 38120
Womens Partner In Health Austin Texas 78705
Health Central Women's Care Dallas Texas 75231
Clinical Research Center of Houston Houston Texas 77054
Texas Tech University Health Sciences Center Lubbock Texas 79430
Texas Tech Health Sciences Center - Odessa Odessa Texas 79763
EVMS Maternal-Fetal Medicine, Hofheimer Hall Norfolk Virginia 23507
West Virginia University Morgantown West Virginia 26506

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00086177, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 18, 2010 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00086177 live on ClinicalTrials.gov.

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