XERECEPT® (hCRF) for Patients Requiring Dexamethasone to Treat Edema Associated With Brain Tumors
Public ClinicalTrials.gov record NCT00088166. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Randomized, Double-Blind, Dexamethasone-Sparing Study Comparing Human Corticotropin-Releasing Factor (hCRF) to Placebo for Control of Symptoms Associated With Peritumoral Brain Edema in Patients With Malignant Brain Tumor Who Require Chronic Administration of High-Dose Dexamethasone
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare the safety and efficacy of XERECEPT® to dexamethasone (Decadron) a common treatment for symptoms of brain swelling (edema). This study is specifically aimed at patients who require chronic high doses of dexamethasone to manage symptoms.
Study identification
- NCT ID
- NCT00088166
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 200 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2004 (Type not available)
- Primary completion
- Mar 2008 (Actual)
- Completion
- Mar 2008 (Actual)
- Last update posted
- Aug 13, 2014
2004 – 2008
United States locations
- U.S. sites
- 27
- U.S. states
- 14
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| UCSF Fresno Center for Clinical Studies | Fresno | California | 93702 | — |
| Hoag Memorial Hospital Presbyterian | Newport Beach | California | 92658 | — |
| Stanford University Medical Center | Palo Alto | California | 94305 | — |
| UC Davis Medical Center, Division of Medical Oncology | Sacramento | California | 95817 | — |
| UC San Diego, Thornton Hospital | San Diego | California | 92037 | — |
| University of Colorado Cancer Center | Aurora | Colorado | 80045 | — |
| Colorado Neurological Institute | Englewood | Colorado | 80113 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| Cancer Institute of Orlando | Orlando | Florida | 32804 | — |
| Moffitt Cancer Center & Research Institute | Tampa | Florida | 33612-9497 | — |
| Winship Cancer Institute, Emory University | Atlanta | Georgia | 30322 | — |
| Northwestern University, Feinberg School of Medicine | Chicago | Illinois | 60611 | — |
| Evanston Northwestern Healthcare | Evanston | Illinois | 60201 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Hermelin Brain Tumor Center, Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Neurology Group of Bergen County | Ridgewood | New Jersey | 07450 | — |
| Dent Neurologic Institute | Amherst | New York | 14226 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10021 | — |
| Weill Medical College of Cornell University | New York | New York | 10021 | — |
| University Hematology Oncology Care, LLC | Cincinnati | Ohio | 43210 | — |
| Good Samaritan Hospital | Cincinnati | Ohio | 45220 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| Oregon Clinic | Portland | Oregon | 97210 | — |
| Virginia Mason Clinic | Seattle | Washington | 98111 | — |
| University of Wisconsin | Madison | Wisconsin | 53792 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226-3596 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00088166, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 13, 2014 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00088166 live on ClinicalTrials.gov.