ClinicalTrials.gov record
Pexelizumab in Patients Undergoing Coronary Artery Bypass Grafting With Cardiopulmonary Bypass (PRIMO-CABG II)
ClinicalTrials.gov ID: NCT00088179
Public ClinicalTrials.gov record NCT00088179. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blind, Parallel-group, Placebo-Controlled Study of Pexelizumab in Patients Undergoing Coronary Artery Bypass Grafting With Cardiopulmonary Bypass (PRIMO-CABG II)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
During a heart bypass procedure, a substance called "complement" is activated by the body. This "complement activation" causes an inflammatory response that can lead to side affects such as chest pain, heart attacks, stroke, heart failure, or death. The purpose of this study is to find out if the study drug (pexelizumab), that blocks "complement activation," can reduce such side effects and be given safely to patients requiring the bypass procedure with the use of the heart-lung machine.
Study identification
- NCT ID
- NCT00088179
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 4,000 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2004
- Primary completion
- Sep 30, 2005
- Completion
- Sep 30, 2005
- Last update posted
- Feb 21, 2018
2004 – 2005
United States locations
- U.S. sites
- 182
- U.S. states
- 40
- U.S. cities
- 132
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Brookwood Medical Center | Birmingham | Alabama | 35209 | — |
| Baptist Medical Center Princeton | Birmingham | Alabama | 35211 | — |
| Baptist Health Systems Montclair | Birmingham | Alabama | 35213 | — |
| Medical Center East Hospital | Birmingham | Alabama | 35235 | — |
| University of Alabama at Birmingham Hospital | Birmingham | Alabama | 35249-6810 | — |
| Thomas Hospital | Fairhope | Alabama | 36532 | — |
| Huntsville Hospital | Huntsville | Alabama | 35801 | — |
| Mobile Infirmary Medical Center | Mobile | Alabama | 36607 | — |
| Banner Good Samaritan Medical Center | Phoenix | Arizona | 85006 | — |
| Arizona Health Sciences Center | Tucson | Arizona | 85724 | — |
| University Medical Center | Tucson | Arizona | 85724 | — |
| Southern Arizona Veterans Affairs Health Care System | Tucson | Arizona | 85732 | — |
| Sparks Regional Medical Center | Fort Smith | Arkansas | 72901 | — |
| Baptist Medical Center | Little Rock | Arkansas | 72205 | — |
| Bakersfield Heart Hospital | Bakersfield | California | 93301 | — |
| Seaton Medical Center | Daly City | California | 94015 | — |
| Palomar Medical Center | Escondido | California | 92025 | — |
| Saddleback Memorial Medical Center | Laguna Hills | California | 92653 | — |
| Los Angeles County-University of Southern California Medical Center | Los Angeles | California | 90033 | — |
| University of Southern California University Hospital | Los Angeles | California | 90033 | — |
| St. Vincent Medical Center | Los Angeles | California | 90057 | — |
| Veterans Administration Greater Los Angeles Healthcare Sysytem | Los Angeles | California | 90073 | — |
| Tri City Medical Center | Oceanside | California | 92056 | — |
| University of California Irvine Medical Center | Orange | California | 92868 | — |
| Veterans Administration Palo Alto Healthcare System | Palo Alto | California | 94304 | — |
| Huntington Memorial Hospital | Pasadena | California | 91105 | — |
| Mercy General Hospital | Sacramento | California | 95819 | — |
| Sharp Memorial Hospital | San Diego | California | 92123 | — |
| Kaiser Permanente Medical Center | San Francisco | California | 94115 | — |
| Porter Adventist Hospital | Denver | Colorado | 80210 | — |
| Presbyterian St.Luke's Medical Center | Denver | Colorado | 80218 | — |
| University of Colorado Health Sciences Center | Denver | Colorado | 80262 | — |
| St. Vincent's Medical Center | Bridgeport | Connecticut | 06606 | — |
| Hospital of Saint Raphael | New Haven | Connecticut | 06511 | — |
| Christiana Hospital | Newark | Delaware | 19718 | — |
| John F. Kennedy Medical Center | Atlantis | Florida | 33462 | — |
| Morton Plant Hospital | Clearwater | Florida | 33756 | — |
| Halifax Medical Center | Daytona Beach | Florida | 32114 | — |
| North Ridge Medical Center | Fort Lauderdale | Florida | 33334 | — |
| Shands Hospital at the University of Florida | Gainesville | Florida | 32610 | — |
| Regional Medical Center Bayonet Point | Hudson | Florida | 34667 | — |
| Baptist Medical Center | Jacksonville | Florida | 32207 | — |
| Memorial Hospital | Jacksonville | Florida | 32216 | — |
| Lakeland Regional Medical Center | Lakeland | Florida | 33805 | — |
| Health First Holmes Regional Medical Center | Melbourne | Florida | 32901 | — |
| Orlando Regional Medical Center | Orlando | Florida | 32801 | — |
| Florida Hospital | Orlando | Florida | 32803 | — |
| Sacred Heart Hospital | Pensacola | Florida | 32504 | — |
| Wuesthoff Hospital | Rockledge | Florida | 32955 | — |
| Sarasota Memorial Hospital | Sarasota | Florida | 34239 | — |
| Northside Hospital and Heart Institute | St. Petersburg | Florida | 33701 | — |
| University Community Hospital | Tampa | Florida | 33613 | — |
| Piedmont Hospital | Atlanta | Georgia | 30309 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Atlanta Veteran's Administration (VA) Medical Center | Decatur | Georgia | 30033 | — |
| Medical Center of Central Georgia | Macon | Georgia | 31208 | — |
| St. Joseph's/Candler Health System | Savannah | Georgia | 31404 | — |
| St. Joseph's/Candler Health System | Savannah | Georgia | 31419 | — |
| Kaiser Permanente Moanalua Medical Center | Honolulu | Hawaii | 96819 | — |
| OSF Saint Francis Medical Center | Peoria | Illinois | 61637 | — |
| Memorial Medical Center | Springfield | Illinois | 62702 | — |
| St. John's Hospital | Springfield | Illinois | 62769 | — |
| Indiana Ohio Heart | Fort Wayne | Indiana | 46804 | — |
| Clarian Health Partners, Inc. Methodist Hospital | Indianapolis | Indiana | 46202 | — |
| The Indiana Heart Hospital | Indianapolis | Indiana | 46250 | — |
| The Heart Center of Indiana | Indianapolis | Indiana | 46290 | — |
| Iowa Heart Center | Des Moines | Iowa | 50314 | — |
| Olathe Medical Center | Olathe | Kansas | 66061 | — |
| Galichia Heart Hospital | Wichita | Kansas | 67202 | — |
| Central Baptist Hospital | Lexington | Kentucky | 40503 | — |
| Veterans Affairs Medical Center | Lexington | Kentucky | 40506 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Jewish Hospital | Louisville | Kentucky | 40202 | — |
| Norton Hospital | Louisville | Kentucky | 40202 | — |
| University of Louisville Hospital | Louisville | Kentucky | 40202 | — |
| Terrebonne General Medical Center | Houma | Louisiana | 70360 | — |
| Louisiana Heart Hospital | Lacombe | Louisiana | 70445 | — |
| Tulane University Hospital and Clinic | New Orleans | Louisiana | 70112 | — |
| Oschner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| Pendleton Memorial Methodist Hospital | New Orleans | Louisiana | 70127 | — |
| Touro Infirmary | New Orleans | Louisiana | — | — |
| Slidell Memorial Hospital | Slidell | Louisiana | 70458 | — |
| Maine Medical Center | Portland | Maine | 04102 | — |
| Sinai Hospital of Baltimore | Baltimore | Maryland | 21215 | — |
| Union Memorial Hospital | Baltimore | Maryland | 21218 | — |
| Peninusla Medical Center | Salisbury | Maryland | 21801 | — |
| St. Joseph Medical Center | Towson | Maryland | 21204 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Cape Cod Hospital | Hyannis | Massachusetts | 02601 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01199 | — |
| Veterans Administration (VA) Boston Healthcare System | West Roxbury | Massachusetts | 02132 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| McLaren Regional Medical Center | Flint | Michigan | 48532 | — |
| Spectrum Health Hospitals | Grand Rapids | Michigan | 49503 | — |
| Borgess Medical Center | Kalamazoo | Michigan | 49048 | — |
| Ingham Regional Medical Center | Lansing | Michigan | 48910 | — |
| West Shore Cardiology Research Department | Muskegon | Michigan | 46444 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| Covenant Medical Center | Saginaw | Michigan | 48601 | — |
| Mayo Clinic College of Medicine | Rochester | Minnesota | 55905 | — |
| St. Luke's Health System | Kansas City | Missouri | 64111 | — |
| Saint Louis University Hospital | St Louis | Missouri | 63110 | — |
| Saint Louis University | St Louis | Missouri | 63110 | — |
| Des Peres Hospital | St Louis | Missouri | 63122 | — |
| Nebraska Heart Hospital | Lincoln | Nebraska | 68506 | — |
| Cooper Hospital University Medical Center | Camden | New Jersey | 08035 | — |
| Cooper Health System/University Medical Center | Camden | New Jersey | 08103 | — |
| Our Lady Of Lourdes Medical Center | Camden | New Jersey | 08103 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Morristown Memorial Hospital | Morristown | New Jersey | 07962-1956 | — |
| Maimondes Medical Center | Brooklyn | New York | 11219 | — |
| United Health Services Hospital | Johnson City | New York | 13790 | — |
| New York Presbyterian Hospital | New York | New York | 10021 | — |
| Mount Sinai Hospital | New York | New York | 10029 | — |
| Vassar Brothers Medical Center | Poughkeepsie | New York | 12601 | — |
| Rochester General Hospital | Rochester | New York | 14621 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Montefiore Medical Center | The Bronx | New York | 10461 | — |
| Westchester Medical Center | Valhalla | New York | 10595 | — |
| University of North Carolina at Chapel Hill Hospitals | Chapel Hill | North Carolina | 27599-7075 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Moses H. Cone Memorial Hospital | Greensboro | North Carolina | 27401 | — |
| Pitt County Memorial Hospital | Greenville | North Carolina | 27858 | — |
| Medcenter One | Bismarck | North Dakota | 58501 | — |
| Akron General Medical Center | Akron | Ohio | 44307 | — |
| The Christ Hospital | Cincinnati | Ohio | 45219 | — |
| Good Samaritan Hospital | Cincinnati | Ohio | 45220 | — |
| Bethesda North Hospital | Cincinnati | Ohio | 45242 | — |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45267-0542 | — |
| University Hospitals Health System | Cleveland | Ohio | 44106-5011 | — |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Riverside Methodist Hospital | Columbus | Ohio | 43214 | — |
| The Dayton Heart Hospital | Dayton | Ohio | 45408 | — |
| The Toledo Hospital | Toledo | Ohio | 43606 | — |
| Good Samaritan Hospital | Zanesville | Ohio | 43701 | — |
| Oklahoma University Medical Center | Oklahoma City | Oklahoma | 73104 | — |
| INTEGRIS Baptist Medical Center | Oklahoma City | Oklahoma | 73112 | — |
| Oklahoma Heart Hospital | Oklahoma City | Oklahoma | 73120 | — |
| St. Charles Medical Center | Bend | Oregon | 97701 | — |
| Legacy Good Samaritan Hospital | Portland | Oregon | 97210 | — |
| Doylestown Hospital | Doylestown | Pennsylvania | 18901 | — |
| St. Mary Medical Center | Langhorne | Pennsylvania | 19067 | — |
| Hahnemann University Hospital | Philadelphia | Pennsylvania | 19102 | — |
| Presbyterian Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Crozer Chester Medical Center | Upland | Pennsylvania | 19013 | — |
| The Chester County Hospital | West Chester | Pennsylvania | 19380 | — |
| Roper St. Francis Healthcare | Charleston | South Carolina | 29401 | — |
| Rapid City Regional Hospital | Rapid City | South Dakota | 57701 | — |
| The Chattanooga Heart Institute | Chattanooga | Tennessee | 37404 | — |
| Jackson-Madison County General Hospital | Jackson | Tennessee | 38301 | — |
| Baptist Memorial Hospital | Memphis | Tennessee | 38120 | — |
| Baptist Hospital | Nashville | Tennessee | 37203 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232-8815 | — |
| Methodist Medical Center | Oak Ridge | Tennessee | 37830 | — |
| Heart Hospital of Austin | Austin | Texas | 78756 | — |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | — |
| Christus Saint Joseph Hospital | Houston | Texas | 77002 | — |
| Michael E. DeBakey Veterans Affairs Medical Center | Houston | Texas | 77030-4298 | — |
| Memorial Hermann Hospital | Houston | Texas | 77030 | — |
| Methodist Hospital | Houston | Texas | 77030 | — |
| St. Luke's Episcopal Hospital - Texas Heart | Houston | Texas | 77030 | — |
| The Methodist Hospital | Houston | Texas | 77030 | — |
| Covenant Medical Center | Lubbock | Texas | 79410 | — |
| TexSan Heart Hospital | San Antonio | Texas | 78201 | — |
| Northeast Baptist Hospital | San Antonio | Texas | 78217 | — |
| University of Utah Hospital | Salt Lake City | Utah | 84132 | — |
| Virginia Hospital Center | Arlington | Virginia | 22205 | — |
| University of Virginia Health System | Charlottesville | Virginia | 22908 | — |
| Inova Fairfax Hospital | Falls Church | Virginia | 22042-3300 | — |
| Memorial Regional Medical Center | Mechanicsville | Virginia | 23116 | — |
| Sentara Norfolk General Hospital | Norfolk | Virginia | 23507 | — |
| CJW Medical Center | Richmond | Virginia | 23225 | — |
| Henrico Doctors' Hospital | Richmond | Virginia | 23229 | — |
| University of Washington Medical Center | Seattle | Washington | 98195-6310 | — |
| Saint Joseph Medical Center | Tacoma | Washington | 98405 | — |
| Charleston Area Medical Center | Charleston | West Virginia | 25304 | — |
| Gundersen Lutheran Medical Center | La Crosse | Wisconsin | 54601 | — |
| St. Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00088179, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 21, 2018 · Synced Sep 12, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00088179 live on ClinicalTrials.gov.