Vaccine Therapy and Sargramostim Compared With Placebo and Sargramostim Following Rituximab in Treating Patients With Non-Hodgkin's Lymphoma
Public ClinicalTrials.gov record NCT00089115. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase III, Randomized, Double Blind, Placebo-Controlled Trial of Favldand GM-CSF Versus Placebo and GM-CSF Following Rituximab in Subjects With Follicular B-Cell Non-Hodgkin's Lymphoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Monoclonal antibodies such as rituximab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Vaccines made from a person's cancer cells may make the body build an immune response to kill cancer cells. Colony-stimulating factors such as GM-CSF increase the number of immune cells found in bone marrow and peripheral blood. It is not yet known whether combining rituximab and GM-CSF with vaccine therapy may cause a stronger immune response and kill more cancer cells. PURPOSE: This randomized phase III trial is studying giving rituximab and GM-CSF together with vaccine therapy and comparing it to giving rituximab and GM-CSF alone in treating patients with newly diagnosed, relapsed, or refractory B-cell non-Hodgkin's lymphoma.
Study identification
- NCT ID
- NCT00089115
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- Not listed
Conditions and interventions
Conditions
Interventions
- autologous immunoglobulin idiotype-KLH conjugate vaccine Biological
- rituximab Biological
- sargramostim Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2004 (Type not available)
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Aug 2, 2013
Started 2004
United States locations
- U.S. sites
- 60
- U.S. states
- 31
- U.S. cities
- 52
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Comprehensive Cancer Center at University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Mayo Clinic Scottsdale | Scottsdale | Arizona | 85259 | — |
| Tower Cancer Research Foundation | Beverly Hills | California | 90211 | — |
| Rebecca and John Moores UCSD Cancer Center | La Jolla | California | 92093-0658 | — |
| Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| USC/Norris Comprehensive Cancer Center and Hospital | Los Angeles | California | 90089 | — |
| Hoag Cancer Center at Hoag Memorial Hospital Presbyterian | Newport Beach | California | 92663 | — |
| Kaiser Permanente Medical Center - Kaiser Foundation Hospital - San Diego | San Diego | California | 92120 | — |
| Sharp Memorial Hospital Cancer Center | San Diego | California | 92123 | — |
| UCSF Comprehensive Cancer Center | San Francisco | California | 94143-0324 | — |
| Stanford Cancer Center at Stanford University Medical Center | Stanford | California | 94305 | — |
| Kaiser Permanente Medical Center - Vallejo | Vallejo | California | 94589 | — |
| Rocky Mountain Cancer Centers - Denver Midtown | Denver | Colorado | 80218 | — |
| Medical Oncology Hematology Consultants, P.A. at Helen F. Graham Cancer Center | Newark | Delaware | 19713-2055 | — |
| Lombardi Cancer Center at Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| Center for Hematology-Oncology - Boca Raton | Boca Raton | Florida | 33486 | — |
| University of Florida Health Science Center - Jacksonville | Jacksonville | Florida | 32209 | — |
| H. Lee Moffitt Cancer Center and Research Institute at University of South Florida | Tampa | Florida | 33612-9497 | — |
| North Idaho Cancer Center | Coeur d'Alene | Idaho | 83814 | — |
| Robert H. Lurie Comprehensive Cancer Center at Northwestern University | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Indiana University Cancer Center | Indianapolis | Indiana | 46202 | — |
| Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center | Kansas City | Kansas | 66160-7357 | — |
| Markey Cancer Center at University of Kentucky Chandler Medical Center | Lexington | Kentucky | 40536-0084 | — |
| Ochsner Cancer Institute at Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| Greater Baltimore Medical Center | Baltimore | Maryland | 21204-6881 | — |
| Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201-1379 | — |
| Josephine Ford Cancer Center at Henry Ford Hospital | Detroit | Michigan | 48202-2608 | — |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | — |
| Siteman Cancer Center at Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| Montana Cancer Specialists at Montana Cancer Center | Missoula | Montana | 59802 | — |
| New Mexico Cancer Center | Albuquerque | New Mexico | 87109 | — |
| North Shore University Hospital | Manhasset | New York | 11030 | — |
| Beth Israel Medical Center - Philipps Ambulatory Care Center | New York | New York | 10003 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10021 | — |
| James P. Wilmot Cancer Center at University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Our Lady of Mercy Medical Center Comprehensive Cancer Center | The Bronx | New York | 10466-2604 | — |
| Comprehensive Cancer Center at Wake Forest University | Winston-Salem | North Carolina | 27157-1082 | — |
| Mid Dakota Clinic, P. C. | Bismarck | North Dakota | 58502-5538 | — |
| Roger Maris Cancer Center at MeritCare Hospital | Fargo | North Dakota | 58122 | — |
| Charles M. Barrett Cancer Center at University Hospital | Cincinnati | Ohio | 45219 | — |
| Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve University | Cleveland | Ohio | 44106-5047 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195 | — |
| Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University | Columbus | Ohio | 43210-1240 | — |
| Providence Cancer Center at Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Kaiser Permanente Medical Office - Interstate Medical Office Central | Portland | Oregon | 97227 | — |
| Cancer Institute at Oregon Health and Science University | Portland | Oregon | 97239-3098 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822-0001 | — |
| Fox Chase-Temple Cancer Center | Philadelphia | Pennsylvania | 19111-2497 | — |
| Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital | Pittsburgh | Pennsylvania | 15224 | — |
| Sarah Cannon Cancer Center at Centennial Medical Center | Nashville | Tennessee | 37203 | — |
| Baylor University Medical Center - Dallas | Dallas | Texas | 75246 | — |
| M.D. Anderson Cancer Center at University of Texas | Houston | Texas | 77030-4009 | — |
| Cancer Care Network of South Texas | San Antonio | Texas | 78229 | — |
| University of Virginia Cancer Center | Charlottesville | Virginia | 22908 | — |
| Swedish Cancer Institute at Swedish Medical Center - First Hill Campus | Seattle | Washington | 98104 | — |
| North Star Lodge Cancer Center at Yakima Valley Memorial Hospital | Yakima | Washington | 98902 | — |
| University of Wisconsin Comprehensive Cancer Center | Madison | Wisconsin | 53792-6164 | — |
| Marshfield Clinic - Marshfield Center | Marshfield | Wisconsin | 54449 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00089115, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 2, 2013 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00089115 live on ClinicalTrials.gov.