ARIES - Ambrisentan in Patients With Moderate to Severe Pulmonary Arterial Hypertension (PAH)
Public ClinicalTrials.gov record NCT00091598. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
ARIES 1 and ARIES 2: Ambrisentan in PAH - A Phase III, Randomized, Double-blind, Placebo-controlled, Multicenter, Efficacy Study of Ambrisentan in Subjects With Pulmonary Arterial Hypertension
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective is to determine the effect of ambrisentan on exercise capacity in subjects with PAH.
Study identification
- NCT ID
- NCT00091598
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 372 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2004 (Type not available)
- Primary completion
- Feb 2006 (Actual)
- Completion
- Feb 2006 (Actual)
- Last update posted
- Mar 8, 2010
2004 – 2006
United States locations
- U.S. sites
- 44
- U.S. states
- 24
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pulmonary Associates, PA | Phoenix | Arizona | 85006 | — |
| Arizona Pulmonary Specialists | Phoenix | Arizona | 85013 | — |
| Brentwood Biomedical Research Institute | Los Angeles | California | 90073 | — |
| University of California-Davis | Sacramento | California | 95817 | — |
| University of California San Diego Medical Center | San Diego | California | 92037 | — |
| Los Angeles County Harbor-UCLA Medical Center | Torrance | California | 90502 | — |
| University of Colorado Health Sciences Center | Denver | Colorado | 80262 | — |
| Myogen | Westminster | Colorado | 80021 | — |
| University of Connecticut Health Center | Farmington | Connecticut | 06030 | — |
| Mt. Sinai Medical Center | Miami | Florida | 33140 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Medical College of Georgia | Augusta | Georgia | 30912 | — |
| Loyola University Medical Center | Chicago | Illinois | 60153 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| Ochsner Clinic | New Orleans | Louisiana | 70121 | — |
| Maine Medical Center | Portland | Maine | 04102 | — |
| Johns Hopkins University | Baltimore | Maryland | 21205 | — |
| Tufts New England Medical Center | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| University of Michigan Medical Center | Ann Arbor | Michigan | 48109 | — |
| Wayne State University | Detroit | Michigan | 48201 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| Northshore University/Long Island Jewish Hospital | Manhasset | New York | 11030 | — |
| Winthrop University Hospital | Mineola | New York | 11501 | — |
| Mt. Sinai Medical Center | New York | New York | 10029 | — |
| New York Presbyterian Hospital | New York | New York | 10032 | — |
| Cardiology PC | Syracuse | New York | 13210 | — |
| Lindner Clinical Trial Center | Cincinnati | Ohio | 45219 | — |
| University Hospitals of Cleveland | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Oregon Health Sciences University | Portland | Oregon | 97202 | — |
| University of Pennsylvania Hospital | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| St. Paul Hospital | Dallas | Texas | 75235 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| University of Texas - San Antonio | San Antonio | Texas | 78229 | — |
| Scott & White Hospital | Temple | Texas | 76508 | — |
| University of Virginia Health System | Charlottesville | Virginia | 22908 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| Heart Care Associates | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00091598, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 8, 2010 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00091598 live on ClinicalTrials.gov.