ClinicalTrials.gov record
Pexelizumab in Conjunction With Angioplasty in Acute Myocardial Infarction (APEX-AMI)
ClinicalTrials.gov ID: NCT00091637
Public ClinicalTrials.gov record NCT00091637. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
APEX-AMI - Pexelizumab in Conjunction With Angioplasty
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
In the setting of reperfusion therapy in an acute myocardial infarction using primary percutaneous intervention (PCI), the body's own inflammatory system involving the complement cascade may be harmful. This study will test the safety and efficacy of a novel complement inhibitor, pexelizumab to reduce mortality at 30 days.
Study identification
- NCT ID
- NCT00091637
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 5,745 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 31, 2004
- Primary completion
- Apr 30, 2007
- Completion
- Apr 30, 2007
- Last update posted
- Nov 17, 2023
2004 – 2007
United States locations
- U.S. sites
- 180
- U.S. states
- 42
- U.S. cities
- 145
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Huntsville Hospital | Huntsville | Alabama | 35801 | — |
| Mayo Clinic Hospital | Phoenix | Arizona | 85054 | — |
| North Phoenix Heart Center | Phoenix | Arizona | — | — |
| Northwest Medical Center | Tucson | Arizona | 85741 | — |
| Sparks Regional Medical Center | Fort Smith | Arkansas | 72901 | — |
| Arkansas State Hospital | Little Rock | Arkansas | 72211 | — |
| Brotman Medical Center | Beverly Hills | California | 90230 | — |
| Providence Saint Joseph Medical Center | Burbank | California | 91505 | — |
| Palomar Medical Center | Escondido | California | 92025 | — |
| Los Angeles Community Hospital | Los Angeles | California | 90033 | — |
| Memorial Medical Center | Modesto | California | 48201 | — |
| Sutter Memorial Hospital | Sacramento | California | 95825 | — |
| University of CA, San Diego Medical | San Diego | California | 92103-8784 | — |
| Sutter Medical Center of Santa Rosa | Santa Rosa | California | 95403 | — |
| Providence Holy Cross Medical Center | Valencia | California | 91355 | — |
| University of Colorado Hospital | Denver | Colorado | 80262 | — |
| St. Vincent Medical Center | Bridgeport | Connecticut | 06606 | — |
| University of Connecticut Health Center | Farmington | Connecticut | 06030-2202 | — |
| Yale - New Haven | New Haven | Connecticut | 06520 | — |
| George Washington University Hospital | Washington D.C. | District of Columbia | 20037 | — |
| JFK Medical Center | Atlantis | Florida | 33462 | — |
| Morton Plant Hospital | Clearwater | Florida | 33756 | — |
| North Ridge Medical Center | Fort Lauderdale | Florida | 33308 | — |
| St. Luke's Hospital | Jacksonville | Florida | 32224 | — |
| Health First Holmes Regional Medical Center | Melbourne | Florida | 32001 | — |
| Florida Heart Hospital | Orlando | Florida | 32803 | — |
| Sarasota Memorial Hospital | Sarasota | Florida | 34239 | — |
| University Community Hospital | Tampa | Florida | 33613 | — |
| St. Luke's Regional Medical Center | Boise | Idaho | 63704 | — |
| Highland Park Hospital | Bannockburn | Illinois | 60015 | — |
| Ingalls Hospital | Harvey | Illinois | 80426 | — |
| Advocate Good Samaritan | Lombard | Illinois | 60148 | — |
| Elmhurst Hospital | Lombard | Illinois | 60148 | — |
| Trinity Medical Center | Moline | Illinois | 61265 | — |
| Saint Francis Medical Center | Peoria | Illinois | 61603 | — |
| Trinity Medical Center | Rock Island | Illinois | 61201 | — |
| Methodist Hospital | Indianapolis | Indiana | 46202 | — |
| VAMC | Indianapolis | Indiana | 46202 | — |
| Community Hospital South | Indianapolis | Indiana | 46227 | — |
| The Indiana Heart Hospital | Indianapolis | Indiana | 56250 | — |
| Munster Community Hospital | Munster | Indiana | 46321 | — |
| Iowa Heart | Des Moines | Iowa | 50314 | — |
| Via Christi Reginal Medical Center | Wichita | Kansas | 67214 | — |
| Central Baptist Hospital | Lexington | Kentucky | 40503 | — |
| University of Kentucky | Lexington | Kentucky | 40536-0200 | — |
| The Jewish Hospital | Louisville | Kentucky | 40202 | — |
| Baptist Hospital East | Louisville | Kentucky | 40207 | — |
| Lousiana Heart Center | Chalmette | Louisiana | 70043 | — |
| Lousiana Heart Hospital | Lacombe | Louisiana | 70445 | — |
| MCLNO at New Orleans University Campus | New Orleans | Louisiana | 70112 | — |
| Tulane University Hospital and Clinic | New Orleans | Louisiana | 70112 | — |
| Eastern Maine Medical Center | Bangor | Maine | 04401 | — |
| Maine Medical Center | Portland | Maine | 04102 | — |
| St. Joseph Medical Center | Towson | Maryland | 21204 | — |
| Oakwood Hospital and Medical Center | Dearborn | Michigan | 48123 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Sinai-Grace Hospital | Detroit | Michigan | 48235 | — |
| Spectrum Health | Grand Rapids | Michigan | 49503 | — |
| Borgess Medical Center | Kalamazoo | Michigan | 49048 | — |
| Mercy General Health Partners | Muskegon | Michigan | 49444 | — |
| Northern Michigan Hospital | Petoskey | Michigan | 49770 | — |
| St. Joseph Mercy-Oakland | Pontiac | Michigan | 48341-2982 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| Covenant Medical Center | Saginaw | Michigan | 48601 | — |
| Saint Mary Medical Center | Saginaw | Michigan | 48601 | — |
| Providence Hospital | Southfield | Michigan | 48075 | — |
| William Beaumont Hospital | Troy | Michigan | 48085 | — |
| Harper University Hospital | Warren | Michigan | 48201 | — |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| St. Mary's Duluth Clinic Health System | Duluth | Minnesota | 55805 | — |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| Abbott Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| North Memorial Medical Center | Minneapolis | Minnesota | 55422 | — |
| Saint Mary Hospital | Rochester | Minnesota | 55902 | — |
| St. Cloud Hospital | Saint Cloud | Minnesota | 56303 | — |
| Methodist Hospital | Saint Louis Park | Minnesota | 55426 | — |
| Health East St. Joseph Hospital | Saint Paul | Minnesota | 55102 | — |
| University of Missouri Health Sciences Center | Columbia | Missouri | 65212 | — |
| St. John's Hospital | Springfield | Missouri | 65807 | — |
| St. Louis University Hospital | St Louis | Missouri | 63110 | — |
| Barnes St. Peters Hospital | St Louis | Missouri | 63122 | — |
| Deaconess Billings Clinic | Billings | Montana | 59101 | — |
| St. Elizabeth Medical Center | Lincoln | Nebraska | 68510 | — |
| Sunrise Hospital | Las Vegas | Nevada | 89109 | — |
| Trinitas Hospital | Elizabeth | New Jersey | 07202 | — |
| St. Joseph's Regional Medical Center | Fair Lawn | New Jersey | 07410 | — |
| New Mexico Heart Institute | Albuquerque | New Mexico | 87102 | — |
| Albany Medical Center | Albany | New York | 12211 | — |
| Maimonides Medical Center | Brooklyn | New York | 11219 | — |
| Wilson Memorial Medical Center | Johnson City | New York | 13790 | — |
| Winthrop University Hospital | Mineola | New York | 11504 | — |
| St. Vincent's Catholic Medical Center | New York | New York | 10011 | — |
| Bellevue Hospital Center | New York | New York | 10016 | — |
| Vassar Brothers Medical Center | Poughkeepsie | New York | 12601 | — |
| Rochester General Hospital | Rochester | New York | 14621 | — |
| SUNY - Upstate Medical University | Syracuse | New York | 13210 | — |
| Monteflore Medical Center | The Bronx | New York | 10467 | — |
| Presbyterian Hospital | Charlotte | North Carolina | 28204 | — |
| Duke University Health Systems | Durham | North Carolina | 27705 | — |
| Moses Cone Hospital/LeBauer Healthcare | Greensboro | North Carolina | 27401 | — |
| Pitt County Memorial Hospital | Greenville | North Carolina | 27834 | — |
| High Point Regional Health System | High Point | North Carolina | 27262 | — |
| Trinity Hospital | Minot | North Dakota | 58701 | — |
| Akron General Medical Center | Akron | Ohio | 44307 | — |
| VAMC Cincinnati | Cincinnati | Ohio | 45220 | — |
| Bethesda North Hospital | Cincinnati | Ohio | 45242 | — |
| The University Hospital | Cincinnati | Ohio | 45267 | — |
| University Hospitals of Cleveland | Cleveland | Ohio | 44103 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| MidWest Cardiology Research Foundation | Columbus | Ohio | 43214 | — |
| Med Central Mansfield | Mansfield | Ohio | 44906 | — |
| Genesis Healthcare System | Zanesville | Ohio | 43701 | — |
| Midwest Regional Medical Center | Midwest City | Oklahoma | 73110 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| VA Medical Center | Oklahoma City | Oklahoma | 73104 | — |
| Integris Baptist Medical Center, Inc. | Oklahoma City | Oklahoma | 73112 | — |
| Oklahoma Heart Hospital | Oklahoma City | Oklahoma | 73120 | — |
| St. Charles Medical Center | Bend | Oregon | 97701 | — |
| Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Lehigh Valley Hospital | Allentown | Pennsylvania | 18105 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822-2160 | — |
| Genesis Medical Center | Davenport | Pennsylvania | 58803 | — |
| Hamot Medical Center | Erie | Pennsylvania | 16550 | — |
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Lancaster General Hospital | Lancaster | Pennsylvania | 17604 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Jefferson Regional Medical Center | Pittsburgh | Pennsylvania | 15025 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Western Pennsylvania Hospital | Pittsburgh | Pennsylvania | 15215 | — |
| VA Pittsburgh Healthcare System | Pittsburgh | Pennsylvania | 15240 | — |
| The Chester County Hospital | West Chester | Pennsylvania | 19380 | — |
| York Hospital | York | Pennsylvania | 17405 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Palmetto Richland Memorial Hospital | Columbia | South Carolina | 29203 | — |
| Sisters of Charity Providence Hospitals | Columbia | South Carolina | 29204 | — |
| Rapid City Regional Hospital | Rapid City | South Dakota | 57719 | — |
| Heart Hospital of South Dakota | Sioux Falls | South Dakota | 57108 | — |
| Jackson-Madison County General Hospital | Jackson | Tennessee | 38301 | — |
| Wellmont Holston Valley Medical Center | Kingsport | Tennessee | 37660 | — |
| Fort Sanders Rgional Medical Center | Knoxville | Tennessee | 37916 | — |
| Baptist Hospital of East Tennessee | Knoxville | Tennessee | 37920 | — |
| Centennial Medical Center | Nashville | Tennessee | 37203 | — |
| Methodist Medical Center | Oak Ridge | Tennessee | 37830 | — |
| Northwest Texas Healthcare System | Amarillo | Texas | 79106 | — |
| Seton Medical Center | Austin | Texas | 78705 | — |
| Presbyterian Hospital of Dallas | Dallas | Texas | 57231 | — |
| Medical City Dallas | Dallas | Texas | 75230 | — |
| Dallas Medical Center | Dallas | Texas | 75390 | — |
| Parkland Health & Hospital System | Dallas | Texas | 75390 | — |
| Brooke Army Medical Center | Fort Sam Houston | Texas | 78234 | — |
| Ben Taub General Hospital | Houston | Texas | 77030 | — |
| Memorial Hermann Hospital | Houston | Texas | 77030 | — |
| Michael E. DeBakey VA Medical Center | Houston | Texas | 77030 | — |
| Houston Northwest Medical Center | Houston | Texas | 77090 | — |
| Covenant Medical Center | Lubbock | Texas | 79410 | — |
| Northeast Baptist Hospital | San Antonio | Texas | 78217 | — |
| South Texas Veterans Health Care System Audie L. Murphy Division | San Antonio | Texas | 78258 | — |
| Scott & White Memorial Hospital | Temple | Texas | 76508 | — |
| East Texas Medical Center | Tyler | Texas | 75701 | — |
| Trinity Mother Frances Hospital | Tyler | Texas | 75701 | — |
| Citizens Medical Center | Victoria | Texas | 77901 | — |
| Detar Hospital | Victoria | Texas | 77901 | — |
| Cottonwood Hospital | Murray | Utah | 84107 | — |
| Inova Alexandria Hospital | Alexandria | Virginia | 22306 | — |
| Universitiy of Virginia Health Science Center | Charlottesville | Virginia | 22908 | — |
| Rockingham Memorial Hospital | Harrisonburg | Virginia | 22801 | — |
| Lynchburg General Hospital | Lynchburg | Virginia | 24501 | — |
| Herrico Doctors' Hospital - Forest | Richmond | Virginia | — | — |
| Sentara Virginia Beach General Hospital | Virginia Beach | Virginia | 23454 | — |
| Winchester Medical Center | Winchester | Virginia | 22601 | — |
| Overtake Hospital Medical Center | Bellevue | Washington | 98004 | — |
| Skagit Valley Hospital | Mount Vernon | Washington | 98274 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
| MultiCare Medical Center (Tacoma General Hospital) | Tacoma | Washington | 98405 | — |
| St. Joseph Medical Center | Tacoma | Washington | 98405 | — |
| West Virginia University Hospital | Morgantown | West Virginia | 26506-9157 | — |
| Franciscan Skemp Healthcare | La Crosse | Wisconsin | 54601 | — |
| Froedtert Hospital | Milwaukee | Wisconsin | 53226 | — |
| Waukesha Memorial Hospital | Waukesha | Wisconsin | 53188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 169 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00091637, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 17, 2023 · Synced Sep 12, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00091637 live on ClinicalTrials.gov.