ClinicalTrials.gov record
Insulin Resistance Intervention After Stroke Trial
ClinicalTrials.gov ID: NCT00091949
Public ClinicalTrials.gov record NCT00091949. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Insulin Resistance Intervention After Stroke (IRIS) Trial
Study identification
- NCT ID
- NCT00091949
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Yale University
- Other
- Enrollment
- 3,876 participants
Conditions and interventions
Conditions
Interventions
- pioglitazone Drug
- placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 31, 2005
- Primary completion
- Oct 31, 2015
- Completion
- Oct 31, 2015
- Last update posted
- Apr 26, 2020
2005 – 2015
United States locations
- U.S. sites
- 99
- U.S. states
- 38
- U.S. cities
- 81
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama | Birmingham | Alabama | 35294-0007 | — |
| University of South Alabama | Mobile | Alabama | 36617-2293 | — |
| University of Arizona | Tucson | Arizona | 85721-5023 | — |
| Shanti Clinical Trials (NINDS-CRC site) | Colton | California | 92324 | — |
| UCSF-Fresno | Fresno | California | 93702 | — |
| Scripps Clinic | La Jolla | California | 92037 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| University of California | Los Angeles | California | 90095 | — |
| Stanford University | Palo Alto | California | 94304 | — |
| University of California-Davis | Sacramento | California | 95817 | — |
| University of California | San Diego | California | 92103-8466 | — |
| University of California | San Francisco | California | 94143-0114 | — |
| Denver Health and Hospital Authority | Denver | Colorado | 80204-4507 | — |
| Hartford | Hartford | Connecticut | 06102-5037 | — |
| Yale University | New Haven | Connecticut | 06519 | — |
| National Rehabilitation Hospital | Washington D.C. | District of Columbia | 20010-2949 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| University of Florida | Jacksonville | Florida | 32209 | — |
| MIMA Century Research Associates | Melbourne | Florida | 32901 | — |
| Pines Neurological Associates (NINDS-CRC site) | Pembroke Pines | Florida | 33026 | — |
| Floria Neurovascular Institute | Tampa | Florida | 33606-3500 | — |
| Cook County (Stroger) Hospital | Chicago | Illinois | 60612 | — |
| Rush University | Chicago | Illinois | 60612 | — |
| University of Illinois | Chicago | Illinois | 60612 | — |
| Ingalls Memorial Hospital (NINDS-CRC site) | Harvey | Illinois | 60426 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| OSF St. Francis Medical Center | Peoria | Illinois | 61637-0001 | — |
| Tri-City Neruology (NINDS-CRC site) | Saint Charles | Illinois | 60175 | — |
| Indiana Medical Research | Elkhart | Indiana | 46514 | — |
| Associates In Neurology (NINDS-CRC site) | Valparaiso | Indiana | 46383 | — |
| Iowa Health Des Moines Clinical Trials Office | Des Moines | Iowa | 50309 | — |
| Ruan Neuroscience Center/Mercy Medical Center | Des Moines | Iowa | 50314 | — |
| University of Iowa | Iowa City | Iowa | 52246 | — |
| Northeast Iowa Medical Education Foundation (NINDS-CRC site) | Waterloo | Iowa | 50702 | — |
| Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| University of Kentucky Research Foundation | Lexington | Kentucky | 40536-0284 | — |
| Louisiana State University Health Sciences Center | Shreveport | Louisiana | 71130-3932 | — |
| Penobscot Bay Neurology | Rockport | Maine | 04856 | — |
| Sinai Hospital of Baltimore | Baltimore | Maryland | 21209 | — |
| Johns Hopkins | Baltimore | Maryland | 21287-6953 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114-2695 | — |
| Boston University | Boston | Massachusetts | 02118 | — |
| Caritas St. Elizabeth's Medical Center | Boston | Massachusetts | 02190 | — |
| Beth Israel Deaconess | Boston | Massachusetts | 02215 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Michigan State University | East Lansing | Michigan | 48824 | — |
| Minneapolis Clinic of Neurology | Robbinsdale | Minnesota | 55426 | — |
| Hattiesburg Clinic (NINDS-CRC site) | Hattiesburg | Mississippi | 39401 | — |
| St. Luke's Brain and Stroke Institute | Kansas City | Missouri | 64111 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| St. John's Mercy Medical Center | St Louis | Missouri | 63141 | — |
| St. Louis University | St Louis | Missouri | 63220 | — |
| Billings Clinic | Billings | Montana | 59101 | — |
| Advanced Neurology Specialists | Great Falls | Montana | 59405 | — |
| University of Nebraska | Omaha | Nebraska | 68198 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Cooper University Hospital | Camden | New Jersey | 08013 | — |
| Kessler Medical Rehab Research Corp | West Orange | New Jersey | 07052 | — |
| University of New Mexico | Albuquerque | New Mexico | 87108 | — |
| Albany Medical Center | Albany | New York | 12208 | — |
| SUNY Downstate | Brooklyn | New York | 11203 | — |
| New York Methodist Hospital | Brooklyn | New York | 11215 | — |
| SUNY Buffalo | Buffalo | New York | 14209 | — |
| St. Vincent's Hospital Manhattan | New York | New York | 10011 | — |
| Cornell University | New York | New York | 10021 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| Southtowns Neurology of WNY (NINDS-CRC site) | West Seneca | New York | 14224 | — |
| Burke Medical Research Institute | White Plains | New York | 10605 | — |
| Clinical Research of Winston-Salem | Winston-Salem | North Carolina | 27103 | — |
| Guilford Neurologic Associates | Winston-Salem | North Carolina | 27103 | — |
| Altru Health System | Grand Forks | North Dakota | 58201 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267-0525 | — |
| Case Western Reserve University | Cleveland | Ohio | 44106-4938 | — |
| Metrohealth Medical Center | Cleveland | Ohio | 44109-1998 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| University of Toledo | Toledo | Ohio | 43614 | — |
| Oregon Health & Science University | Portland | Oregon | 97239-3098 | — |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| Lankenau Institute for Medical Research | Bryn Mawr | Pennsylvania | 19010 | — |
| Penn Stat-Hershey Medical Center (NINDS-CRC site) | Hershey | Pennsylvania | 17033 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107-5083 | — |
| Temple University | Philadelphia | Pennsylvania | 19140 | — |
| Allegheny Singer Research Institute | Pittsburgh | Pennsylvania | 15212 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213-2582 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02905 | — |
| University of Tennessee | Memphis | Tennessee | 38163 | — |
| Vanderbilt | Nashville | Tennessee | 37212 | — |
| Baylor Research Institute | Dallas | Texas | 75246 | — |
| University of Texas, Southwestern | Dallas | Texas | 75390-8897 | — |
| Methodist Neurological Institute | Houston | Texas | 77030 | — |
| University of Texas | San Antonio | Texas | 78229-3900 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| University of Vermont | Burlington | Vermont | 05405 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| Sentara Medical Group | Norfolk | Virginia | 23507 | — |
| University of Wisconsin | Madison | Wisconsin | 53792 | — |
| Marshfield Clinic | Marshfield | Wisconsin | 54449 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226-3596 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 84 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00091949, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 26, 2020 · Synced May 14, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00091949 live on ClinicalTrials.gov.