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Completed Phase 3 Interventional

Clevidipine in the Perioperative Treatment of Hypertension (ECLIPSE-NTG)

ClinicalTrials.gov ID: NCT00093886

Public ClinicalTrials.gov record NCT00093886. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 31, 2026, 9:54 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Evaluation of Clevidipine in the Perioperative Treatment of Hypertension Assessing Safety Events (With Nitroglycerin as Active Comparator) (ECLIPSE-NTG)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to establish the safety of clevidipine in the treatment of perioperative hypertension. Approximately 500-900 patients with perioperative hypertension undergoing coronary artery bypass grafting (CABG), off-pump coronary artery bypass (OPCAB) or minimally invasive direct coronary artery bypass (MIDCAB) surgery and/or valve replacement/repair procedures were anticipated to be randomly assigned to one of two treatment groups: clevidipine or nitroglycerin.

Study identification

NCT ID
NCT00093886
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
The Medicines Company
Industry
Enrollment
629 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 2004 (Type not available)
Primary completion
Mar 2005 (Actual)
Completion
Apr 2005 (Actual)
Last update posted
May 6, 2014

2004 – 2005

United States locations

U.S. sites
28
U.S. states
15
U.S. cities
22
Facility City State ZIP Site status
Brookwood Medical Center Birmingham Alabama 35209 —
Baptist Medical Center, Montclair Birmingham Alabama 35213 —
Medical Center East Birmingham Alabama 35235 —
Baptist Medical Center, South Montgomery Alabama 36116 —
University Medical Center Tucson Arizona 85724 —
Saddleback Memorial Medical Center Laguna Hills California 92653 —
Keck School of Medicine, University of Southern California Los Angeles California 90033 —
Huntington Memorial Hospital Pasadena California 91109 —
University of California San Francisco California 94143-0648 —
Regional Medical Center - Bayonet Point Hudson Florida 34667 —
Health First Holmes Regional Medical Center Melbourne Florida 32901 —
Sacred Heart Health System Pensacola Florida 32504 —
Kaiser Permanente Moanalua Medical Center Honolulu Hawaii 96817 —
Saint Francis Hospital Evanston Illinois 60202 —
Wesley Medical Center Wichita Kansas 67214 —
St Joseph Medical Center Towson Maryland 21204 —
Henry Ford Health System Detroit Michigan 48202 —
New York University Medical Center New York New York 10016 —
Sterling Research Group, Ltd. Cincinnati Ohio 45219 —
The Christ Hospital, The Linder Clinical Trial Center Cincinnati Ohio 45219 —
Portland VA Medical Center Portland Oregon 97239 —
Memorial Herman Memorial City Hospital Houston Texas 77024 —
Michael E DeBakey VA Medical Center Houston Texas 77030-4211 —
The Methodist Hospital Houston Texas 77030 —
Houston Northwest Medical Center Houston Texas 77090 —
Inova Fairfax Hospital Falls Church Virginia 22042 —
Virginia Commonwealth University Medical Center Richmond Virginia 23298 —
Saint Joseph Medical Center Tacoma Washington 98405 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00093886, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 6, 2014 · Synced Oct 31, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00093886 live on ClinicalTrials.gov.

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