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Completed Phase 3 Interventional

Clevidipine in the Perioperative Treatment of Hypertension (ECLISPE-SNP)

ClinicalTrials.gov ID: NCT00093912

Public ClinicalTrials.gov record NCT00093912. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 11, 2026, 8:45 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Evaluation of Clevidipine in the Perioperative Treatment of Hypertension Assessing Safety Events (With Sodium Nitroprusside as Active Comparator) (ECLISPE-SNP)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to establish the safety of clevidipine in the treatment of perioperative hypertension. Approximately 250-500 patients with perioperative hypertension undergoing coronary artery bypass grafting (CABG), off-pump coronary artery bypass (OPCAB) or minimally invasive direct coronary artery bypass (MIDCAB) surgery and/or valve replacement/repair procedures were anticipated to be randomly assigned to one of two treatment groups: clevidipine or sodium nitroprusside.

Study identification

NCT ID
NCT00093912
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
The Medicines Company
Industry
Enrollment
739 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 2004 (Type not available)
Primary completion
Oct 2006 (Actual)
Completion
Nov 2006 (Actual)
Last update posted
May 6, 2014

2004 – 2006

United States locations

U.S. sites
29
U.S. states
21
U.S. cities
25
Facility City State ZIP Site status
Saint Vincents Hospital Birmingham Alabama 35205 —
Brookwood Medical Center Birmingham Alabama 35209 —
Baptist Medical Center, Montclair Birmingham Alabama 35213 —
Baptist Medical Center, South Montgomery Alabama 36101 —
Drug Research and Analysis Corporation Montgomery Alabama 36106 —
Providence Saint Joseph Medical Center Burbank California 91505 —
Stanford University Medical Center Stanford California 94305 —
Shands Hospital at the University of Florida Gainesville Florida 32610 —
Health First Holmes Regional Medical Center Melbourne Florida 32901 —
Kaiser Permanente Honolulu Hawaii 96817 —
St. Francis Hospital and Health Center Blue Island Illinois 60406 —
St. Francis Hospital of Evanston Evanston Illinois 60202 —
Wesley Medical Center Wichita Kansas 67214 —
Touro Infirmary New Orleans Louisiana 70115 —
Ochsner Clinic Foundation New Orleans Louisiana 70121 —
St. Joseph Medical Center Towson Maryland 21204 —
Massachussettes General Hospital Boston Massachusetts 02114 —
Henry Ford Health System Detroit Michigan 48202 —
Saint Lukes Hospital Duluth Minnesota 55805 —
International Heart Institute/St. Patrick Hospital Missoula Montana 59802 —
Mt. Sinai Medical Center New York New York 10029-6574 —
The Christ Hospital Cincinnati Ohio 45219 —
Portland VA Medical Center Portland Oregon 97239 —
Hospital of the University of Pennsylvania Philadelphia Pennsylvania 19104 —
Jackson-Madison County General Hospital Jackson Tennessee 38301 —
Houston Northwest Medical Center Houston Texas 77090 —
LDS Hospital Salt Lake City Utah 84112 —
Virginia Commonwealth University Medical Center Richmond Virginia 23298 —
Medical College of Wisconsin VAMC - Milwaukee Milwaukee Wisconsin 53295 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00093912, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 6, 2014 · Synced Nov 11, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00093912 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →