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Completed Phase 3 Interventional

Clevidipine in the Postoperative Treatment of Hypertension (ECLIPSE-NIC)

ClinicalTrials.gov ID: NCT00093925

Public ClinicalTrials.gov record NCT00093925. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 6:31 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Evaluation of Clevidipine in the Postoperative Treatment of Hypertension Assessing Safety Events (With Nicardipine as Active Comparator) (ECLIPSE-NIC)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to establish the safety of clevidipine in the treatment of postoperative hypertension. Approximately 250-500 patients with postoperative hypertension after undergoing coronary artery bypass grafting (CABG), off-pump coronary artery bypass (OPCAB) or minimally invasive direct coronary artery bypass (MIDCAB) surgery and/or valve replacement/repair procedures were anticipated to be randomly assigned to one of two treatment groups: clevidipine or nicardipine.

Study identification

NCT ID
NCT00093925
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
The Medicines Company
Industry
Enrollment
739 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2004
Primary completion
Jun 30, 2006
Completion
Aug 31, 2006
Last update posted
May 5, 2014

2004 – 2006

United States locations

U.S. sites
9
U.S. states
6
U.S. cities
7
Facility City State ZIP Site status
Mobile Infirmary Medical Center Mobile Alabama 36607
Wesley Medical Center Wichita Kansas 67214
Touro Infirmary New Orleans Louisiana 70115
Ochsner Clinic Foundation New Orleans Louisiana 70121
Columbia University - College of Physicians and Surgeons New York New York 10032
Jack D. Weller Hospital The Bronx New York 10461
Montefiore Medical Center The Bronx New York 10467
Hospital of the University of Pennsylvania Philadelphia Pennsylvania 19104
VA Medical Center McGuire Richmond Virginia 23249

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00093925, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 5, 2014 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00093925 live on ClinicalTrials.gov.

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