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Completed Phase 2 Interventional Results available

Cilengitide (EMD 121974) for Recurrent Glioblastoma Multiforme (Brain Tumor)

ClinicalTrials.gov ID: NCT00093964

Public ClinicalTrials.gov record NCT00093964. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 12:31 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Open-label, Randomized, Uncontrolled, Phase IIa Trial in Subjects With Recurrent Glioblastoma Multiforme to Investigate the Clinical Activity, Safety, and Tolerability of Cilengitide (EMD 121,974) Administered as a Single Agent.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will investigate clinical activity, safety, and tolerability of the anti-angiogenic compound cilengitide (EMD 121974) in the treatment of first recurrence of glioblastoma multiforme (GBM).

Study identification

NCT ID
NCT00093964
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
EMD Serono
Industry
Enrollment
81 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 13, 2004 (Actual)
Primary completion
Oct 28, 2005 (Actual)
Completion
Oct 21, 2010 (Actual)
Last update posted
Apr 16, 2019

2004 – 2010

United States locations

U.S. sites
17
U.S. states
15
U.S. cities
17
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35294-3280 —
Barrow Neurological Institute Phoenix Arizona 85013 —
UCLA Medical Center Los Angeles California 90095 —
Denise Damek Aurora Colorado 80010 —
Northwestern University Chicago Illinois 60611 —
Indiana University Medical Center Indianapolis Indiana 46202 —
Massachusetts General Hospital Boston Massachusetts 02114 —
University of Massachusetts Worcester Massachusetts 01655 —
Henry Ford Health System Detroit Michigan 48202 —
Washington University St Louis Missouri 63110 —
Memorial Sloan Kettering Cancer Center New York New York 10021 —
Duke University Medical Center Durham North Carolina 27710 —
Good Samaritan Hospital/Tri Health Hatton Center Cincinnati Ohio 45206 —
Baylor University Medical Center at Dallas Dallas Texas 75246 —
University of Texas MD Anderson Cancer Center Houston Texas 77030 —
University of Vermont/Fletcher Allen Healthcare Burlington Vermont 05401 —
University of Virginia Health System Charlottesville Virginia 22903 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00093964, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 16, 2019 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00093964 live on ClinicalTrials.gov.

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