ClinicalTrials.gov record
Lenalidomide and Dexamethasone With or Without Thalidomide in Treating Patients With Multiple Myeloma
ClinicalTrials.gov ID: NCT00098475
Public ClinicalTrials.gov record NCT00098475. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Phase III Study of CC-5013 Plus Dexamethasone Versus CC-5013 Plus Low Dose Dexamethasone in Multiple Myeloma With Thalidomide Plus Dexamethasone Salvage Therapy for Non-Responders
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This randomized phase III trial studies lenalidomide and low-dose dexamethasone to see how well it works compared to lenalidomide and standard-dose dexamethasone, given with or without thalidomide, in treating patients with multiple myeloma. Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells from growing. Lenalidomide and thalidomide may also stop the growth of multiple myeloma by blocking blood flow to the cancer. Drugs used in chemotherapy, such as dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving lenalidomide, thalidomide, and dexamethasone together may kill more cancer cells.
Study identification
- NCT ID
- NCT00098475
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 452 participants
Conditions and interventions
Interventions
- Dexamethasone Drug
- Laboratory Biomarker Analysis Other
- Lenalidomide Drug
- Thalidomide Drug
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 3, 2004 (Actual)
- Primary completion
- Nov 30, 2008 (Actual)
- Completion
- Oct 23, 2026 (Estimated)
- Last update posted
- Aug 28, 2026
2004 – 2026
United States locations
- U.S. sites
- 138
- U.S. states
- 35
- U.S. cities
- 118
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham Cancer Center | Birmingham | Alabama | 35233 | — |
| Huntsville Hospital | Huntsville | Alabama | 35801 | — |
| Providence Alaska Medical Center | Anchorage | Alaska | 99508 | — |
| Mayo Clinic in Arizona | Scottsdale | Arizona | 85259 | — |
| Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California | 91505 | — |
| Saint Jude Medical Center | Fullerton | California | 92835 | — |
| El Camino Hospital | Mountain View | California | 94040 | — |
| Kaiser Permanente-Rio San Diego | San Diego | California | 92108 | — |
| The Medical Center of Aurora | Aurora | Colorado | 80012 | — |
| Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | 80907 | — |
| Saint Joseph Hospital - Cancer Centers of Colorado | Denver | Colorado | 80218 | — |
| Swedish Medical Center | Englewood | Colorado | 80113 | — |
| Poudre Valley Hospital | Fort Collins | Colorado | 80524 | — |
| Banner North Colorado Medical Center - Loveland Campus | Loveland | Colorado | 80539 | — |
| Danbury Hospital | Danbury | Connecticut | 06810 | — |
| Eastern Connecticut Hematology and Oncology Associates | Norwich | Connecticut | 06360 | — |
| Holy Cross Hospital | Fort Lauderdale | Florida | 33308 | — |
| UF Health Cancer Institute - Gainesville | Gainesville | Florida | 32610 | — |
| Baptist MD Anderson Cancer Center | Jacksonville | Florida | 32207 | — |
| Mayo Clinic in Florida | Jacksonville | Florida | 32224-9980 | — |
| Martin Hospital South | Stuart | Florida | 34997 | — |
| Phoebe Putney Memorial Hospital | Albany | Georgia | 31701 | — |
| Emory University Hospital/Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| Atlanta Regional CCOP | Atlanta | Georgia | 30342 | — |
| Augusta Oncology Associates PC-D'Antignac | Augusta | Georgia | 30901 | — |
| Emory Decatur Hospital | Decatur | Georgia | 30033 | — |
| Atrium Health Navicent | Macon | Georgia | 31201 | — |
| Lewis Cancer and Research Pavilion at Saint Joseph's/Candler | Savannah | Georgia | 31405 | — |
| University of Hawaii Cancer Center | Honolulu | Hawaii | 96813 | — |
| Saint Luke's Cancer Institute - Boise | Boise | Idaho | 83712 | — |
| OSF Saint Anthony's Health Center | Alton | Illinois | 62002 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| John H Stroger Jr Hospital of Cook County | Chicago | Illinois | 60612 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Ascension Alexian Brothers - Elk Grove Village | Elk Grove Village | Illinois | 60007 | — |
| Edward Hines Jr VA Hospital | Hines | Illinois | 60141 | — |
| Midwest Center for Hematology Oncology | Joliet | Illinois | 60432 | — |
| Duly Health and Care Joliet | Joliet | Illinois | 60435 | — |
| Swedish American Hospital | Rockford | Illinois | 61104 | — |
| UW Health Carbone Cancer Center Rockford | Rockford | Illinois | 61114 | — |
| Edward H Kaplan MD and Associates | Skokie | Illinois | 60076 | — |
| Elkhart General Hospital | Elkhart | Indiana | 46515 | — |
| Fort Wayne Medical Oncology and Hematology Inc-Parkview | Fort Wayne | Indiana | 46845 | — |
| Indiana University/Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202 | — |
| Franciscan Health Indianapolis | Indianapolis | Indiana | 46237 | — |
| IU Health Arnett Cancer Care | Lafayette | Indiana | 47904 | — |
| Saint Joseph Regional Medical Center-Mishawaka | Mishawaka | Indiana | 46545 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| McFarland Clinic - Ames | Ames | Iowa | 50010 | — |
| University of Iowa Healthcare Cancer Services Quad Cities | Bettendorf | Iowa | 52722 | — |
| Iowa Methodist Medical Center | Des Moines | Iowa | 50309 | — |
| Siouxland Regional Cancer Center | Sioux City | Iowa | 51101 | — |
| MercyOne Waterloo Cancer Center | Waterloo | Iowa | 50702 | — |
| Kansas City NCI Community Oncology Research Program | Prairie Village | Kansas | 66208 | — |
| Harold Alfond Center for Cancer Care | Augusta | Maine | 04330 | — |
| Greater Baltimore Medical Center | Baltimore | Maryland | 21204 | — |
| HealthAlliance Hospital - Leominster | Leominster | Massachusetts | 01453 | — |
| Henry Ford Health Saint John Hospital | Detroit | Michigan | 48236 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | — |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| Unity Hospital | Fridley | Minnesota | 55432 | — |
| Saint John's Hospital - Healtheast | Maplewood | Minnesota | 55109 | — |
| Mayo Clinic in Rochester | Rochester | Minnesota | 55905 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| Mercy Hospital Saint Louis | St Louis | Missouri | 63141 | — |
| Saint Louis-Cape Girardeau CCOP | St Louis | Missouri | 63141 | — |
| Montana Cancer Consortium NCORP | Billings | Montana | 59102 | — |
| Great Falls Clinic | Great Falls | Montana | 59405 | — |
| Nebraska Cancer Research Center | Lincoln | Nebraska | 68510 | — |
| Nebraska Methodist Hospital | Omaha | Nebraska | 68114 | — |
| Alegent Health Immanuel Medical Center | Omaha | Nebraska | 68122 | — |
| Alegent Health Bergan Mercy Medical Center | Omaha | Nebraska | 68124 | — |
| Midlands Community Hospital | Papillion | Nebraska | 68046 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| The Cancer Institute of New Jersey Hamilton | Hamilton | New Jersey | 08690 | — |
| Morristown Medical Center | Morristown | New Jersey | 07960 | — |
| Virtua Memorial | Mount Holly | New Jersey | 08060 | — |
| Jersey Shore Medical Center | Neptune City | New Jersey | 07753 | — |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08903 | — |
| Robert Wood Johnson University Hospital Somerset | Somerville | New Jersey | 08876 | — |
| Garnet Health Medical Center | Middletown | New York | 10940 | — |
| NYU Langone Hospital - Long Island | Mineola | New York | 11501 | — |
| Mount Sinai Union Square | New York | New York | 10003 | — |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | — |
| Mission Hospital | Asheville | North Carolina | 28801 | — |
| Wayne Memorial Hospital | Goldsboro | North Carolina | 27534 | — |
| Southeast Clinical Oncology Research Consortium NCORP | Winston-Salem | North Carolina | 27104 | — |
| Sanford Bismarck Medical Center | Bismarck | North Dakota | 58501 | — |
| Essentia Health Cancer Center-South University Clinic | Fargo | North Dakota | 58103 | — |
| Sanford Broadway Medical Center | Fargo | North Dakota | 58122 | — |
| Summa Health System - Akron Campus | Akron | Ohio | 44304 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| Miami Valley Hospital North | Dayton | Ohio | 45415 | — |
| Atrium Medical Center-Middletown Regional Hospital | Franklin | Ohio | 45005-1066 | — |
| Kettering Medical Center | Kettering | Ohio | 45429 | — |
| Saint Charles Hospital | Oregon | Ohio | 43616 | — |
| Firelands Regional Medical Center | Sandusky | Ohio | 44870 | — |
| ProMedica Flower Hospital | Sylvania | Ohio | 43560 | — |
| Mercy Hospital of Tiffin | Tiffin | Ohio | 44883 | — |
| Toledo Community Hospital Oncology Program CCOP | Toledo | Ohio | 43617 | — |
| Toledo Clinic Cancer Centers-Toledo | Toledo | Ohio | 43623 | — |
| Kaiser Permanente Northwest | Portland | Oregon | 97227 | — |
| Jefferson Abington Hospital | Abington | Pennsylvania | 19001 | — |
| Penn State Milton S Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| Lancaster General Hospital | Lancaster | Pennsylvania | 17602 | — |
| Saint Mary Medical and Regional Cancer Center | Langhorne | Pennsylvania | 19047 | — |
| University of Pennsylvania/Abramson Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| Pennsylvania Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Temple Health - Chestnut Hill Hospital | Philadelphia | Pennsylvania | 19118 | — |
| Einstein Medical Center Philadelphia | Philadelphia | Pennsylvania | 19141 | — |
| Guthrie Medical Group PC-Robert Packer Hospital | Sayre | Pennsylvania | 18840 | — |
| Grand View Hospital | Sellersville | Pennsylvania | 18960 | — |
| Mount Nittany Medical Center | State College | Pennsylvania | 16803 | — |
| Reading Hospital | West Reading | Pennsylvania | 19611 | — |
| Lankenau Medical Center | Wynnewood | Pennsylvania | 19096 | — |
| WellSpan Health-York Hospital | York | Pennsylvania | 17403 | — |
| McLeod Regional Medical Center | Florence | South Carolina | 29506 | — |
| Rapid City Regional Hospital | Rapid City | South Dakota | 57701 | — |
| Sanford Cancer Center Oncology Clinic | Sioux Falls | South Dakota | 57104 | — |
| University of Virginia Cancer Center | Charlottesville | Virginia | 22908 | — |
| Sentara Martha Jefferson Hospital | Charlottesville | Virginia | 22911 | — |
| Centra Alan B Pearson Regional Cancer Center | Lynchburg | Virginia | 24501 | — |
| VCU Massey Comprehensive Cancer Center | Richmond | Virginia | 23298 | — |
| Swedish Medical Center-First Hill | Seattle | Washington | 98122 | — |
| West Virginia University Healthcare | Morgantown | West Virginia | 26506 | — |
| ThedaCare Regional Cancer Center | Appleton | Wisconsin | 54911 | — |
| Gundersen Lutheran Medical Center | La Crosse | Wisconsin | 54601 | — |
| SSM Health Dean Medical Group - South Madison Campus | Madison | Wisconsin | 53715 | — |
| University of Wisconsin Carbone Cancer Center - University Hospital | Madison | Wisconsin | 53792 | — |
| Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | 54449 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
| ProHealth Oconomowoc Memorial Hospital | Oconomowoc | Wisconsin | 53066 | — |
| ProHealth Waukesha Memorial Hospital | Waukesha | Wisconsin | 53188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00098475, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 28, 2026 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00098475 live on ClinicalTrials.gov.