ClinicalTrials.gov record
Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
ClinicalTrials.gov ID: NCT00099125
Public ClinicalTrials.gov record NCT00099125. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Study Of Radiation Therapy Plus Low Dose Temozolomide Followed By Temozolomide Plus Irinotecan For Glioblastoma Multiforme
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy, such as temozolomide and irinotecan, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy with chemotherapy may kill more tumor cells. PURPOSE: This phase II trial is studying how well radiation therapy, temozolomide, and irinotecan work in treating patients with newly diagnosed glioblastoma multiforme.
Study identification
- NCT ID
- NCT00099125
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 170 participants
Conditions and interventions
Conditions
Interventions
- irinotecan hydrochloride Drug
- temozolomide Drug
- adjuvant therapy Procedure
- radiation therapy Radiation
Drug · Procedure · Radiation
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 31, 2004
- Primary completion
- Sep 30, 2006
- Completion
- Oct 31, 2013
- Last update posted
- Jan 23, 2014
2004 – 2013
United States locations
- U.S. sites
- 118
- U.S. states
- 31
- U.S. cities
- 94
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Foundation for Cancer Research and Education | Phoenix | Arizona | 85013 | — |
| Providence Saint Joseph Medical Center - Burbank | Burbank | California | 91505 | — |
| Saint Agnes Medical Center | Fresno | California | 93720 | — |
| Loma Linda University Cancer Institute at Loma Linda University Medical Center | Loma Linda | California | 92354 | — |
| Providence Holy Cross Cancer Center | Mission Hills | California | 91346-9600 | — |
| Pomona Valley Hospital Medical Center | Pomona | California | 91767 | — |
| Radiological Associates of Sacramento Medical Group, Inc. | Sacramento | California | 95815 | — |
| Yale Comprehensive Cancer Center at Yale University School of Medicine | New Haven | Connecticut | 06520-8032 | — |
| CCOP - Christiana Care Health Services | Newark | Delaware | 19718 | — |
| University of Florida Shands Cancer Center | Gainesville | Florida | 32610 | — |
| Baptist Cancer Institute - Jacksonville | Jacksonville | Florida | 32207 | — |
| John B. Amos Community Cancer Center | Columbus | Georgia | 31904 | — |
| Regional Radiation Oncology Center at Rome | Rome | Georgia | 30165 | — |
| Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center | Boise | Idaho | 83706 | — |
| Northwest Community Hospital | Arlington Heights | Illinois | 60005 | — |
| Robert H. Lurie Comprehensive Cancer Center at Northwestern University | Chicago | Illinois | 60611-3013 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637-1470 | — |
| Ingalls Cancer Care Center at Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Cardinal Bernardin Cancer Center at Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| St. Francis Hospital and Health Centers | Beech Grove | Indiana | 46107 | — |
| Tulane Cancer Center | New Orleans | Louisiana | 70112 | — |
| CCOP - Ochsner | New Orleans | Louisiana | 70121 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109 | — |
| Josephine Ford Cancer Center at Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | — |
| Regional Cancer Center at Singing River Hospital | Pascagoula | Mississippi | 39581 | — |
| Cancer Institute of Cape Girardeau | Cape Girardeau | Missouri | 63703 | — |
| CCOP - Cancer Research for the Ozarks | Springfield | Missouri | 65802 | — |
| St. John's Regional Health Center | Springfield | Missouri | 65804 | — |
| Hulston Cancer Center at Cox Medical Center South | Springfield | Missouri | 65807 | — |
| Siteman Cancer Center at Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| Methodist Cancer Center at Methodist Hospital - Omaha | Omaha | Nebraska | 68114 | — |
| CCOP - Southern Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | — |
| Dartmouth - Hitchcock Concord | Concord | New Hampshire | 03301 | — |
| Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Cancer Institute of New Jersey at the Cooper University Hospital | Camden | New Jersey | 08103 | — |
| Cooper Cancer Institute | Camden | New Jersey | 08103 | — |
| John F. Kennedy Medical Center | Edison | New Jersey | 08818 | — |
| Monmouth Medical Center | Long Branch | New Jersey | 07740 | — |
| Community Medical Center | Toms River | New Jersey | 08755 | — |
| University of New Mexico Cancer Research and Treatment Center | Albuquerque | New Mexico | 87106 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Lipson Cancer and Blood Center at Rochester General Hospital | Rochester | New York | 14621 | — |
| James P. Wilmot Cancer Center at University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Randolph Hospital | Asheboro | North Carolina | 27203 | — |
| Mission Hospitals - Memorial Campus | Asheville | North Carolina | 28801 | — |
| John Smith, Jr./Dalton McMichael Cancer Center at Morehead Memorial Hospital | Eden | North Carolina | 27288 | — |
| Wayne Radiation Oncology | Goldsboro | North Carolina | 27534 | — |
| Moses Cone Regional Cancer Center at Wesley Long Community Hospital | Greensboro | North Carolina | 27401 | — |
| Annie Penn Cancer Center | Reidsville | North Carolina | 27320 | — |
| Akron City Hospital | Akron | Ohio | 44304 | — |
| McDowell Cancer Center at Akron General Medical Center | Akron | Ohio | 44307 | — |
| Radiation Oncology Center | Alliance | Ohio | 44601 | — |
| Aultman Hospital Cancer Center at Aultman Health Foundation | Canton | Ohio | 44710 | — |
| Charles M. Barrett Cancer Center at University Hospital | Cincinnati | Ohio | 45267 | — |
| CCOP - Columbus | Columbus | Ohio | 43215 | — |
| Grandview Hospital | Dayton | Ohio | 45405 | — |
| David L. Rike Cancer Center at Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| Veterans Affairs Medical Center - Dayton | Dayton | Ohio | 45428 | — |
| Charles F. Kettering Memorial Hospital | Kettering | Ohio | 45429 | — |
| Middletown Regional Hospital | Middletown | Ohio | 45044 | — |
| Cancer Research UK Medical Oncology Unit at Churchill Hospital & Weatherall Institute of Molecular Medicine - Oxford | Salem | Ohio | 44460 | — |
| UVMC Cancer Care Center at Upper Valley Medical Center | Troy | Ohio | 45373 | — |
| Cancer Treatment Center | Wooster | Ohio | 44691 | — |
| Ruth G. McMillan Cancer Center at Greene Memorial Hospital | Xenia | Ohio | 45385 | — |
| Natalie Warren Bryant Cancer Center at St. Francis Hospital | Tulsa | Oklahoma | 74136 | — |
| Legacy Mount Hood Medical Center | Glesham | Oregon | 97030 | — |
| Providence Milwaukie Hospital | Milwaukie | Oregon | 97222 | — |
| Comprehensive Cancer Center at Legacy Good Samaritan Hospital & Medical Center | Portland | Oregon | 97210 | — |
| Providence Cancer Center at Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| CCOP - Columbia River Oncology Program | Portland | Oregon | 97225 | — |
| Providence St. Vincent Medical Center | Portland | Oregon | 97225 | — |
| Institute of Oncology at Vilnius University | Portland | Oregon | 97227 | — |
| Legacy Meridian Park Hospital | Tualatin | Oregon | 97062 | — |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| John and Dorothy Morgan Cancer Center at Lehigh Valley Hospital | Allentown | Pennsylvania | 18105 | — |
| St. Luke's Hospital Cancer Center | Bethlehem | Pennsylvania | 18015 | — |
| Bryn Mawr Hospital | Bryn Mawr | Pennsylvania | 19010 | — |
| UPMC Cancer Center - Arnold Palmer Pavilion | Greensburg | Pennsylvania | 15601 | — |
| Penn State Cancer Institute at Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| UPMC McKeesport | McKeesport | Pennsylvania | 15132 | — |
| Paoli Memorial Hospital | Paoli | Pennsylvania | 19301 | — |
| Kimmel Cancer Center at Thomas Jefferson University - Philadelphia | Philadelphia | Pennsylvania | 19107 | — |
| Albert Einstein Cancer Center | Philadelphia | Pennsylvania | 19141 | — |
| Allegheny Cancer Center at Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Hillman Cancer Center at University of Pittsburgh Cancer Institute | Pittsburgh | Pennsylvania | 15213 | — |
| UPMC Cancer Center at Magee-Womens Hospital | Pittsburgh | Pennsylvania | 15213 | — |
| UPMC Cancer Center at UPMC Presbyterian | Pittsburgh | Pennsylvania | 15213 | — |
| UPMC St. Margaret | Pittsburgh | Pennsylvania | 15215 | — |
| Mercy Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15219 | — |
| UPMC - Shadyside | Pittsburgh | Pennsylvania | 15232 | — |
| UPMC - Passavant Hospital | Pittsburgh | Pennsylvania | 15237 | — |
| Cancer Center at St. Clair Memorial Hospital | Pittsburgh | Pennsylvania | 15243 | — |
| Reading Hospital and Medical Center | West Reading | Pennsylvania | 19612 | — |
| CCOP - MainLine Health | Wynnewood | Pennsylvania | 19096 | — |
| Lankenau Cancer Center at Lankenau Hospital | Wynnewood | Pennsylvania | 19096 | — |
| York Cancer Center at Wellspan Health | York | Pennsylvania | 17405 | — |
| Hollings Cancer Center at Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| CCOP - Upstate Carolina | Spartanburg | South Carolina | 29304 | — |
| Rapid City Regional Hospital | Rapid City | South Dakota | 57701 | — |
| Cottonwood Hospital Medical Center | Murray | Utah | 84107 | — |
| McKay-Dee Hospital Center | Ogden | Utah | 84403 | — |
| Utah Valley Regional Medical Center - Provo | Provo | Utah | 84603 | — |
| Utah Cancer Specialists at UCS Cancer Center | Salt Lake City | Utah | 84106 | — |
| LDS Hospital | Salt Lake City | Utah | 84143 | — |
| Dixie Regional Medical Center | St. George | Utah | 84770 | — |
| Green Mountain Oncology Group | Bennington | Vermont | 05201 | — |
| Fletcher Allen Health Care - University Health Center Campus | Burlington | Vermont | 05401 | — |
| Community Cancer Center at Rutland Regional Medical Center | Rutland | Vermont | 05701 | — |
| Massey Cancer Center at Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| CCOP - Virginia Mason Research Center | Seattle | Washington | 98101 | — |
| Southwest Washington Medical Center Cancer Center | Vancouver | Washington | 98668 | — |
| North Star Lodge Cancer Center | Yakima | Washington | 98902 | — |
| St. Vincent Hospital | Green Bay | Wisconsin | 54301 | — |
| Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center | La Crosse | Wisconsin | 54601 | — |
| University of Wisconsin Comprehensive Cancer Center | Madison | Wisconsin | 53792 | — |
| Community Memorial Hospital | Menomonee Falls | Wisconsin | 53051 | — |
| Medical College of Wisconsin Cancer Center | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00099125, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 23, 2014 · Synced Sep 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00099125 live on ClinicalTrials.gov.