Safety, Effectiveness, and Tolerability of Ezetimibe Combined With Statins for the Treatment of High Cholesterol in HIV Infected Adults
Public ClinicalTrials.gov record NCT00099684. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Pilot Study of the Safety, Efficacy, and Tolerability of Ezetimibe (Zetia) in Combination With Statin Therapy for the Treatment of Elevated LDL Cholesterol in HIV-Infected Subjects
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Anti-HIV drugs, especially protease inhibitors (PIs), have been linked to lipid metabolism problems, including elevations in low density lipoprotein cholesterol (LDL-c), triglycerides, and total cholesterol. Ezetimibe is a lipid-controlling drug; statins are part of another class of lipid-lowering drugs popularly prescribed to people with high cholesterol. The purpose of this study is to determine the safety, effectiveness, and tolerability of ezetimibe in combination with statin therapy in adults who are taking anti-HIV drugs and have high cholesterol. Study hypothesis: In HIV infected adults, ezetimibe in combination with statin therapy will result in significantly lower LDL-c compared to statin therapy alone.
Study identification
- NCT ID
- NCT00099684
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 44 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 2005 (Type not available)
- Primary completion
- Not listed
- Completion
- May 2007 (Actual)
- Last update posted
- Oct 29, 2012
2005 – 2007
United States locations
- U.S. sites
- 41
- U.S. states
- 17
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35924-2050 | — |
| UCLA School of Medicine | Los Angeles | California | 77555-0435 | — |
| University of Southern California | Los Angeles | California | 90033-1079 | — |
| University of California, San Diego Antiviral Research Center | San Diego | California | 92103 | — |
| San Francisco General Hospital | San Francisco | California | 94110 | — |
| San Mateo County AIDS Program | Stanford | California | 94305-5107 | — |
| Santa Clara Valley Medical Center | Stanford | California | 94305-5107 | — |
| Stanford University | Stanford | California | 94305-5107 | — |
| Willow Clinic | Stanford | California | 94305-5107 | — |
| Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| University of Miami | Miami | Florida | 33136-1013 | — |
| University of Hawaii | Honolulu | Hawaii | 96816-2396 | — |
| Rush-Presbyterian/St. Lukes (Chicago) | Chicago | Illinois | 60611-3015 | — |
| Cook County Hospital Core Center | Chicago | Illinois | 60612 | — |
| Feinberg School of Medicine, HIV/ACTU | Chicago, 60611-3015 | Illinois | 60611-3015 | — |
| Indiana University Hospital | Indianapolis | Indiana | 46202-5250 | — |
| Wishard Hospital | Indianapolis | Indiana | 46202 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455-0392 | — |
| Nebraska Health System | Omaha | Nebraska | 68198-5130 | — |
| SUNY - Buffalo (Rochester) | Buffalo | New York | 14215 | — |
| Beth Israel Medical Center | New York | New York | 10003 | — |
| Chelsea Clinic | New York | New York | 10011 | — |
| NYU/Bellevue | New York | New York | 10016-6481 | — |
| The Cornell Clinical Trials Unit | New York | New York | 10021 | — |
| Columbia University | New York | New York | 10032-3784 | — |
| Community Health Network, Inc. | Rochester | New York | 14642-0001 | — |
| University of Rochester Medical Center | Rochester | New York | 14642-0001 | — |
| Duke University Medical Center | Durham | North Carolina | — | — |
| University of Cincinnati | Cincinnati | Ohio | 45267-0405 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109-1998 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Presbyterian Medical Center - Univ. of PA | Philadelphia | Pennsylvania | 19104 | — |
| University of Pennsylvania, Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213-2582 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02906 | — |
| Stanley Street Treatment and Resource | Providence | Rhode Island | 02906 | — |
| The Miriam Hospital | Providence | Rhode Island | 02906 | — |
| Comprehensive Care Clinic | Nashville | Tennessee | 37203 | — |
| Dallas VA Medical Center | Dallas | Texas | 75235-9173 | — |
| University of Texas, Galveston | Galveston | Texas | 77555-0435 | — |
| University of Washington (Seattle) | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00099684, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 29, 2012 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00099684 live on ClinicalTrials.gov.