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ClinicalTrials.gov record
Completed Phase 3 Interventional

18-Month Study of the Efficacy of Xaliproden (SR57746A) in Patients With Mild-to-Moderate Dementia of the Alzheimer's Type

ClinicalTrials.gov ID: NCT00103649

Public ClinicalTrials.gov record NCT00103649. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 9:56 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Multicenter, Double-Blind, Placebo-Controlled, 18-Month Study of the Efficacy of Xaliproden in Patients With Mild-to-Moderate Dementia of the Alzheimer's Type

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to assess xaliproden's potential capacity of slowing the deterioration of cognitive and global functions in patients with mild to moderate Alzheimer's disease. The patients participating in this study will take orally once daily xaliproden or placebo (inactive substance pill).

Study identification

NCT ID
NCT00103649
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Sanofi
Industry
Enrollment
1,306 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 2003 (Type not available)
Primary completion
Oct 2007 (Actual)
Completion
Oct 2007 (Actual)
Last update posted
Aug 21, 2008

2003 – 2007

United States locations

U.S. sites
97
U.S. states
33
U.S. cities
88
Facility City State ZIP Site status
UAB Memory Disorders Clinic Birmingham Alabama 35294-0017 —
Barrow Neurology Clinics Phoenix Arizona 85013 —
PsyPharma Clinical Research, Inc. Phoenix Arizona 85050 —
Radiant Research Scottsdale Arizona 85251 —
Anaheim Research Center Anaheim California 92801 —
Margolin Brain Institute Fresno California 93720 —
Coordinated Clinical Research La Jolla California 92037 —
Senior Clinical Trials, Inc. Laguna Hills California 92653 —
Pharmacology Research Institute Newport Beach California 92660 —
Pharmacology Research Institute Northridge California 91324 —
Pharmacology Research Institute Riverside California 92506 —
Pacific Research Network San Diego California 92103 —
California Neuroscience Research Medical Group Sherman Oaks California 91403 —
Pacific Research Network Vista California 92083 —
Radiant Research Denver Colorado 80212 —
Associated Neurologist Danbury Connecticut 06810 —
Geriatric and Adult Psychiatry, LLC Hamden Connecticut 06518 —
Yale University School of Medicine AD Research Unit New Haven Connecticut 06510 —
Healthcore Newark Delaware 19713-2094 —
Neurology Associates, PA Wilmington Delaware 19806 —
Atlantic Institute of Clinical Research Daytona Beach Florida 32114 —
Berma Research Group Hialeah Florida 33016 —
Miami Research Associates Miami Florida 33173 —
Baumel-Eisner Neuromedical Institute in Miami Beach Miami Florida — —
Baumel-Eisner Neuromedical Institute Miami Florida — —
Anchor Research Center Naples Florida 34102 —
Segal Institute for Clinical Research North Miami Florida 33161 —
Clinical Neuroscience Solutions Orlando Florida 32806 —
Palm Beach Neurological Center Palm Beach Gardens Florida 33410 —
Neurology Clinical Research, Inc. Plantation Florida 33324 —
CNS Clinical Trials St. Petersburg Florida 33702 —
Baumel-Eisner Neuromedical Institute in Miami Beach Tamarac Florida — —
Meridien Research Tampa Florida 33609 —
Suncoast Gerontology Center USF Tampa Florida 33617 —
Radiant Research Marietta Georgia 30060 —
Southeastern Geriatric Healthcare Snellville Georgia 30078 —
Chicago Center for Clinical Research Chicago Illinois 60610 —
Radiant Research Center Hoffman Estates Illinois 60194 —
Elkhart Clinic, LLC Elkhart Indiana 46514 —
Ruan Neurology Des Moines Iowa 50314 —
Four Rivers Clinical Research Paducah Kentucky 42003 —
Louisiana Research Associates New Orleans Louisiana 70114 —
J. Gary Booker MD Shreveport Louisiana 71101 —
Clinical Insights Glen Burnie Maryland 21061 —
Summit Research Network Michigan, Inc. Okemos Michigan 48864 —
Pivotal Research Centers, Detroit Office Royal Oak Michigan 48073 —
Minneapolis VA Medical Center Minneapolis Minnesota 55417 —
Radiant Research Las Vegas Nevada 89146 —
ClinSearch, Inc. Kenilworth New Jersey 07033 —
The Neuroscience Center of Northern New Jersey Morristown New Jersey 07960 —
Princeton Medical Institute Princeton New Jersey 08540 —
Neurology Group of Bergen County Ridgewood New Jersey 07450 —
Lovelace Scientific Resources Albuquerque New Mexico 87108 —
Neurological Association of Albany P.C. Albany New York 12208 —
Social Psychiatry Research Institute Brooklyn New York 11235 —
Parker Jewish Institute for Healthcare and Rehabilitation Hyde Park New York 11021 —
Neurobehavioral Research, Inc. Lawrence New York 11559 —
Eastside Comprehensive Medical Center New York New York 10021 —
Behavioral Medical Research of Staten Island New York New York 10305 —
Global Research and Consulting Olean New York 14760 —
Duke University Medical Center (DUMC) - Dept. of Psychiatry Durham North Carolina 27710 —
MedARK Clinical Research Morganton North Carolina 28655 —
Piedmont Medical Research Assoc, Inc. Winston-Salem North Carolina 27103 —
DayStar Clinical Research, Inc. Akron Ohio 44313 —
North East Ohio Health Services Beachwood Ohio 44122 —
Valley Medical Primary Care Centerville Ohio 45459 —
Remington-Davis Clinical Research Columbus Ohio 43215 —
Triphase Research, Ltd. Franklin Ohio 45005 —
TriPhase Research Franklin Ohio 45005 —
Neurology and Neuroscience Center of Ohio Toledo Ohio 43623 —
Radiant Research Eugene Eugene Oregon 97455 —
Clinical Research Institute of Southern Oregon Medford Oregon 97504 —
Summit Research Network Inc Portland Oregon 97210 —
Coatesville VA Medical Center Coatesville Pennsylvania 19320 —
Pearl Clinical Research Norristown Pennsylvania 19401 —
Memory Disorders Clinic Philadelphia Pennsylvania 19104 —
Radiant Research Philadelphia Pennsylvania 19115 —
Clinical Trials Research Services Pittsburgh Pennsylvania 15206 —
JRMC Clinical Trials Center Pittsburgh Pennsylvania 15236 —
RI Mood and Memory East Providence Rhode Island 02914 —
Memorial Hospital of Rhode Island Pawtucket Rhode Island 02860 —
Avera Research Institute Sioux Falls South Dakota 57105 —
CNS Healthcare Memphis Tennessee 38119 —
Vanderbilt University Medical Center - Geriatric Psychiatry Nashville Tennessee 37212 —
University of Texas - Southwestern Medical Center at Dallas Dallas Texas 75390-9129 —
Houston Sleep Center Houston Texas 77024 —
AD Research Center Houston Texas 77030 —
Innovative Clinical Trials San Antonio Texas 78229 —
North Texas Neurology Research Wichita Falls Texas 76301 —
Radiant Research SLC Salt Lake City Utah 84107 —
The Memory Clinic Bennington Vermont 05201 —
Charlottesville Medical Research Charlottesville Virginia 22911 —
Internal Medicine Northwest Tacoma Washington 98405 —
Wenatchee Valley Medical Center Wenatchee Washington 98801 —
Dean Foundation Middleton Wisconsin 53562 —
Medical College of Wisconsin Milwaukee Wisconsin 53226 —
IPC Research Waukesha Wisconsin 53188 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00103649, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 21, 2008 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00103649 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →