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Completed Phase 3 Interventional

18-Month Study of the Efficacy of Xaliproden (SR57746A) in Patients With Mild-to-Moderate Dementia of the Alzheimer's Type

ClinicalTrials.gov ID: NCT00103649

Public ClinicalTrials.gov record NCT00103649. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 2:29 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Multicenter, Double-Blind, Placebo-Controlled, 18-Month Study of the Efficacy of Xaliproden in Patients With Mild-to-Moderate Dementia of the Alzheimer's Type

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to assess xaliproden's potential capacity of slowing the deterioration of cognitive and global functions in patients with mild to moderate Alzheimer's disease. The patients participating in this study will take orally once daily xaliproden or placebo (inactive substance pill).

Study identification

NCT ID
NCT00103649
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Sanofi
Industry
Enrollment
1,306 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 31, 2003
Primary completion
Sep 30, 2007
Completion
Sep 30, 2007
Last update posted
Aug 20, 2008

2003 – 2007

United States locations

U.S. sites
97
U.S. states
33
U.S. cities
88
Facility City State ZIP Site status
UAB Memory Disorders Clinic Birmingham Alabama 35294-0017
Barrow Neurology Clinics Phoenix Arizona 85013
PsyPharma Clinical Research, Inc. Phoenix Arizona 85050
Radiant Research Scottsdale Arizona 85251
Anaheim Research Center Anaheim California 92801
Margolin Brain Institute Fresno California 93720
Coordinated Clinical Research La Jolla California 92037
Senior Clinical Trials, Inc. Laguna Hills California 92653
Pharmacology Research Institute Newport Beach California 92660
Pharmacology Research Institute Northridge California 91324
Pharmacology Research Institute Riverside California 92506
Pacific Research Network San Diego California 92103
California Neuroscience Research Medical Group Sherman Oaks California 91403
Pacific Research Network Vista California 92083
Radiant Research Denver Colorado 80212
Associated Neurologist Danbury Connecticut 06810
Geriatric and Adult Psychiatry, LLC Hamden Connecticut 06518
Yale University School of Medicine AD Research Unit New Haven Connecticut 06510
Healthcore Newark Delaware 19713-2094
Neurology Associates, PA Wilmington Delaware 19806
Atlantic Institute of Clinical Research Daytona Beach Florida 32114
Berma Research Group Hialeah Florida 33016
Miami Research Associates Miami Florida 33173
Baumel-Eisner Neuromedical Institute in Miami Beach Miami Florida
Baumel-Eisner Neuromedical Institute Miami Florida
Anchor Research Center Naples Florida 34102
Segal Institute for Clinical Research North Miami Florida 33161
Clinical Neuroscience Solutions Orlando Florida 32806
Palm Beach Neurological Center Palm Beach Gardens Florida 33410
Neurology Clinical Research, Inc. Plantation Florida 33324
CNS Clinical Trials St. Petersburg Florida 33702
Baumel-Eisner Neuromedical Institute in Miami Beach Tamarac Florida
Meridien Research Tampa Florida 33609
Suncoast Gerontology Center USF Tampa Florida 33617
Radiant Research Marietta Georgia 30060
Southeastern Geriatric Healthcare Snellville Georgia 30078
Chicago Center for Clinical Research Chicago Illinois 60610
Radiant Research Center Hoffman Estates Illinois 60194
Elkhart Clinic, LLC Elkhart Indiana 46514
Ruan Neurology Des Moines Iowa 50314
Four Rivers Clinical Research Paducah Kentucky 42003
Louisiana Research Associates New Orleans Louisiana 70114
J. Gary Booker MD Shreveport Louisiana 71101
Clinical Insights Glen Burnie Maryland 21061
Summit Research Network Michigan, Inc. Okemos Michigan 48864
Pivotal Research Centers, Detroit Office Royal Oak Michigan 48073
Minneapolis VA Medical Center Minneapolis Minnesota 55417
Radiant Research Las Vegas Nevada 89146
ClinSearch, Inc. Kenilworth New Jersey 07033
The Neuroscience Center of Northern New Jersey Morristown New Jersey 07960
Princeton Medical Institute Princeton New Jersey 08540
Neurology Group of Bergen County Ridgewood New Jersey 07450
Lovelace Scientific Resources Albuquerque New Mexico 87108
Neurological Association of Albany P.C. Albany New York 12208
Social Psychiatry Research Institute Brooklyn New York 11235
Parker Jewish Institute for Healthcare and Rehabilitation Hyde Park New York 11021
Neurobehavioral Research, Inc. Lawrence New York 11559
Eastside Comprehensive Medical Center New York New York 10021
Behavioral Medical Research of Staten Island New York New York 10305
Global Research and Consulting Olean New York 14760
Duke University Medical Center (DUMC) - Dept. of Psychiatry Durham North Carolina 27710
MedARK Clinical Research Morganton North Carolina 28655
Piedmont Medical Research Assoc, Inc. Winston-Salem North Carolina 27103
DayStar Clinical Research, Inc. Akron Ohio 44313
North East Ohio Health Services Beachwood Ohio 44122
Valley Medical Primary Care Centerville Ohio 45459
Remington-Davis Clinical Research Columbus Ohio 43215
Triphase Research, Ltd. Franklin Ohio 45005
TriPhase Research Franklin Ohio 45005
Neurology and Neuroscience Center of Ohio Toledo Ohio 43623
Radiant Research Eugene Eugene Oregon 97455
Clinical Research Institute of Southern Oregon Medford Oregon 97504
Summit Research Network Inc Portland Oregon 97210
Coatesville VA Medical Center Coatesville Pennsylvania 19320
Pearl Clinical Research Norristown Pennsylvania 19401
Memory Disorders Clinic Philadelphia Pennsylvania 19104
Radiant Research Philadelphia Pennsylvania 19115
Clinical Trials Research Services Pittsburgh Pennsylvania 15206
JRMC Clinical Trials Center Pittsburgh Pennsylvania 15236
RI Mood and Memory East Providence Rhode Island 02914
Memorial Hospital of Rhode Island Pawtucket Rhode Island 02860
Avera Research Institute Sioux Falls South Dakota 57105
CNS Healthcare Memphis Tennessee 38119
Vanderbilt University Medical Center - Geriatric Psychiatry Nashville Tennessee 37212
University of Texas - Southwestern Medical Center at Dallas Dallas Texas 75390-9129
Houston Sleep Center Houston Texas 77024
AD Research Center Houston Texas 77030
Innovative Clinical Trials San Antonio Texas 78229
North Texas Neurology Research Wichita Falls Texas 76301
Radiant Research SLC Salt Lake City Utah 84107
The Memory Clinic Bennington Vermont 05201
Charlottesville Medical Research Charlottesville Virginia 22911
Internal Medicine Northwest Tacoma Washington 98405
Wenatchee Valley Medical Center Wenatchee Washington 98801
Dean Foundation Middleton Wisconsin 53562
Medical College of Wisconsin Milwaukee Wisconsin 53226
IPC Research Waukesha Wisconsin 53188

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00103649, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 20, 2008 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00103649 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →