Study of the Human Anti-TNF Monoclonal Antibody Adalimumab for the Induction of Clinical Remission in Subjects With Crohn's Disease
Public ClinicalTrials.gov record NCT00105300. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Human Anti-TNF Monoclonal Antibody Adalimumab for the Induction of Clinical Remission in Subjects With Moderate to Severe Crohn's Disease Who Have Lost Response or Are Intolerant to Infliximab
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goal of this study is to test whether adalimumab can induce clinical remission in subjects with active Crohn's disease who have been initially treated with infliximab and either lost response or discontinued its use as a result of intolerance to the drug.
Study identification
- NCT ID
- NCT00105300
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 300 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2004 (Type not available)
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Aug 15, 2006
Started 2004
United States locations
- U.S. sites
- 46
- U.S. states
- 26
- U.S. cities
- 44
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Associates | Huntsville | Alabama | 35801 | — |
| Capitol Gastroenterology Consultants Medical Group, Inc. | Roseville | California | 95661 | — |
| Medical Associates Research Group | San Diego | California | 92123 | — |
| Sharp Rees-Stealy Medical Group | San Diego | California | 92123 | — |
| SMC-Trauma Research | Englewood | Colorado | 80113 | — |
| Clinical Research of West Florida, Inc | Clearwater | Florida | 33765 | — |
| V.A. Medical Center | Gainesville | Florida | 32608 | — |
| Borland-Groover Clinic | Jacksonville | Florida | 32256 | — |
| Shafran Gastroenterology Center | Winter Park | Florida | 32789 | — |
| Pinnacle Trials, Inc. | Atlanta | Georgia | 30329 | — |
| Atlanta Gastroenterology Assoc. | Atlanta | Georgia | 30342 | — |
| The University of Chicago | Chicago | Illinois | 60673 | — |
| Ntouch Research | Peoria | Illinois | 60602 | — |
| Outpatient Clinical Research Facility University of Indianapolis | Indianapolis | Indiana | 462025250 | — |
| University of Kentucky Medical Center Division of Digestive Diseases | Lexington | Kentucky | 40536 | — |
| Drug Research Services, Inc. | Metairie | Louisiana | 70001 | — |
| Chevy Chase Clinical Research | Chevy Chase | Maryland | 20815 | — |
| Charm City Research | Towson | Maryland | 21204 | — |
| Minnesota Gastroenterology P.A. | Plymouth | Minnesota | 55446 | — |
| Mayo Clinic Research | Rochester | Minnesota | 559050002 | — |
| Gastrointestinal Associated, P.A. | Jackson | Mississippi | 39202 | — |
| Glen Gordon, MD | Mexico | Missouri | 65265 | — |
| St. Louis Center for Clinical Research | St Louis | Missouri | 63128 | — |
| Atlantic Gastroenterology Associates, LLC | Egg Harbor | New Jersey | 08234 | — |
| Long Island Clinical Research Assoc. LLP | Great Neck | New York | 11021 | — |
| NY Center for Clinical Research | Lake Success | New York | 11042 | — |
| Mount Sinai School of Medicine IBD Research Center | New York | New York | 10029 | — |
| Asheville Gastroenterology Associates | Ashville | North Carolina | 28801 | — |
| Wake Research Associates | Raleigh | North Carolina | 27612 | — |
| Consultants for Clinical Research | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Gastrointestinal and Liver Disease Consultants | Dayton | Ohio | 45440 | — |
| Gastroenterology Associates of Cleveland | Mayfield Heights | Ohio | 44124 | — |
| The Oregon Clinic, PC Gastroenterology Division | Portland | Oregon | 97220 | — |
| Regional Gastroenterologist Associates of Lancaster | Lancaster | Pennsylvania | 17604 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15261 | — |
| Columbia Gastro Associates | Columbia | South Carolina | 29204 | — |
| Gastrointestinal Associates | Knoxville | Tennessee | 37909 | — |
| Gastroenterology Center of the Mid South | Memphis | Tennessee | 38120 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Austin Gastroenterology | Austin | Texas | 78745 | — |
| Wasatch Clinical Research | Salt Lake City | Utah | 84107 | — |
| Internal Medicine Associates | Danville | Virginia | 25451 | — |
| Digestive and Liver Disease | Norfolk | Virginia | 23205 | — |
| Spokane Digestive Disease Center | Spokane | Washington | 99204 | — |
| Discovery Research International, LLC | Milwaukee | Wisconsin | 53207 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00105300, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 15, 2006 · Synced Nov 9, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00105300 live on ClinicalTrials.gov.