A Study to Assess the Effect of Tocilizumab + DMARD Therapy on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis
Public ClinicalTrials.gov record NCT00106574. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind Study of the Effect of Tocilizumab on Reduction in Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis and Inadequate Response to DMARD Therapy
Study identification
- NCT ID
- NCT00106574
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 1,220 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- tocilizumab [RoActemra/Actemra] Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 31, 2005
- Primary completion
- Nov 30, 2007
- Completion
- Nov 30, 2007
- Last update posted
- Nov 1, 2016
2005 – 2007
United States locations
- U.S. sites
- 76
- U.S. states
- 33
- U.S. cities
- 74
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Mesa | Arizona | 85208 | — |
| Not listed | Paradise Valley | Arizona | 85253 | — |
| Not listed | Peoria | Arizona | 85381 | — |
| Not listed | Scottsdale | Arizona | 85258 | — |
| Not listed | Tucson | Arizona | 85723 | — |
| Not listed | Little Rock | Arkansas | 72205 | — |
| Not listed | Los Angeles | California | 90048 | — |
| Not listed | Palm Desert | California | 92260 | — |
| Not listed | Palo Alto | California | 94304 | — |
| Not listed | San Jose | California | 95126 | — |
| Not listed | Upland | California | 91786 | — |
| Not listed | Newark | Delaware | 19713 | — |
| Not listed | Washington D.C. | District of Columbia | 20006 | — |
| Not listed | Delray Beach | Florida | 33484 | — |
| Not listed | Jupiter | Florida | 33458 | — |
| Not listed | Palm Habor | Florida | 34684 | — |
| Not listed | Palm Harbor | Florida | 34684 | — |
| Not listed | Tampa | Florida | 33609 | — |
| Not listed | Chicago | Illinois | 60611 | — |
| Not listed | Chicago | Illinois | 60637 | — |
| Not listed | Springfield | Illinois | 62704 | — |
| Not listed | Vernon Hills | Illinois | 60061 | — |
| Not listed | Indianapolis | Indiana | 46202 | — |
| Not listed | Bowling Green | Kentucky | 42102 | — |
| Not listed | Baton Rouge | Louisiana | 70808 | — |
| Not listed | Shreverport | Louisiana | 71103 | — |
| Not listed | Frederick | Maryland | 21702 | — |
| Not listed | Boston | Massachusetts | 02111 | — |
| Not listed | Lansing | Michigan | 48910 | — |
| Not listed | Duluth | Minnesota | 55805 | — |
| Not listed | Eagan | Minnesota | 55121 | — |
| Not listed | Saint Louis Park | Minnesota | 55426 | — |
| Not listed | Springfield | Missouri | 65807 | — |
| Not listed | St Louis | Missouri | 63117 | — |
| Not listed | Lincoln | Nebraska | 68516 | — |
| Not listed | Reno | Nevada | 89502 | — |
| Not listed | Clifton | New Jersey | 07012 | — |
| Not listed | Haddon Heights | New Jersey | 08035 | — |
| Not listed | New Brunswick | New Jersey | 08903 | — |
| Not listed | Albuquerque | New Mexico | 87131 | — |
| Not listed | New York | New York | 10021 | — |
| Not listed | Plainview | New York | 11803 | — |
| Not listed | Roslyn | New York | 11576 | — |
| Not listed | Smithtown | New York | 11787 | — |
| Not listed | Syracuse | New York | 13210 | — |
| Not listed | Durham | North Carolina | 27704 | — |
| Not listed | Raleigh | North Carolina | 27609 | — |
| Not listed | Winston-Salem | North Carolina | 27157 | — |
| Not listed | Beachwood | Ohio | 44122 | — |
| Not listed | Cincinnati | Ohio | 45219 | — |
| Not listed | Dayton | Ohio | 45408 | — |
| Not listed | Gallipolis | Ohio | 45631 | — |
| Not listed | Oklahoma City | Oklahoma | 73103 | — |
| Not listed | Oklahoma City | Oklahoma | 73112 | — |
| Not listed | Tulsa | Oklahoma | 74104 | — |
| Not listed | Medford | Oregon | 97504 | — |
| Not listed | Allentown | Pennsylvania | 18103 | — |
| Not listed | Bethlehem | Pennsylvania | 18015 | — |
| Not listed | Philadelphia | Pennsylvania | 19152 | — |
| Not listed | Pittsburgh | Pennsylvania | 15261 | — |
| Not listed | Rockledge | Pennsylvania | 19046 | — |
| Not listed | Willow Grove | Pennsylvania | 19090 | — |
| Not listed | Johnston | Rhode Island | 02919 | — |
| Not listed | Charleston | South Carolina | 29406 | — |
| Not listed | Hixson | Tennessee | 37343 | — |
| Not listed | Nashville | Tennessee | 37203 | — |
| Not listed | Austin | Texas | 78705 | — |
| Not listed | Houston | Texas | 77074 | — |
| Not listed | Mesquite | Texas | 75150 | — |
| Not listed | Burlington | Vermont | 05401 | — |
| Not listed | Arlington | Virginia | 22204 | — |
| Not listed | Spokane | Washington | 99204 | — |
| Not listed | Tacoma | Washington | 98405 | — |
| Not listed | Vancouver | Washington | 98664 | — |
| Not listed | La Crosse | Wisconsin | 54601 | — |
| Not listed | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 70 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00106574, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 1, 2016 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00106574 live on ClinicalTrials.gov.