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Completed Phase 3 Interventional Results available

The Safety and Efficacy of Escitalopram in Pediatric Patients With Major Depressive Disorder

ClinicalTrials.gov ID: NCT00107120

Public ClinicalTrials.gov record NCT00107120. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 22, 2026, 7:15 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Double-blind Flexible Dose Study of Escitalopram in Pediatric Patients With Major Depressive Disorder

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Depression affects approximately 2.5% of children and 8% of adolescents. Escitalopram is the S-enantiomer of citalopram. Both escitalopram and citalopram are selective serotonin reuptake inhibitors (SSRIs) and are used to treat depression in adults. This study is designed to provide a systematic evaluation of the safety and efficacy of escitalopram in the treatment of depressed pediatric patients, 12 to 17 years of age. Patients completing the study will be eligible to enter an open-label extension study.

Study identification

NCT ID
NCT00107120
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Forest Laboratories
Industry
Enrollment
312 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
12 Years to 17 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2005
Primary completion
Apr 30, 2007
Completion
Not listed
Last update posted
Apr 5, 2012

Started 2005

United States locations

U.S. sites
28
U.S. states
18
U.S. cities
26
Facility City State ZIP Site status
University of California at Davis, MIND Institute, Health Services Sacramento California 95817
UCSD Outpatient Psychiatry Services San Diego California 92103
PCSD - Feighner Research San Diego California 92111
Children's National Medical Center Washington D.C. District of Columbia 20010
University of Florida - Child Study Program Gainesville Florida 32610
Clinical Neuroscience Solutions, Inc. Jacksonville Florida 32216
Janus Center for Psychiatric Research West Palm Beach Florida 33407
Kolin Research Group Winter Park Florida 32789
Capstone Clinical Research Libertyville Illinois 60048
Clinco Terre Haute Indiana 47802
Psychiatric Associates Overland Kansas 66211
Pharmasite Research, Inc. Baltimore Maryland 21208
Capitol Clinical Research Associates Rockville Maryland 20852
St. Charles Psychiatric Associates Saint Charles Missouri 63301
Creighton University Medical School, Department of Psychiatry Omaha Nebraska 68131
CNS Research Institute Clementon New Jersey 08021
Pulmonary and Allergy Associates, P. A. Summit New Jersey 07901
North Carolina Neuropsychiatry, PA Chapel Hill North Carolina 27514
University of Cincinnati College of Medicine, Children's Hospital Medical Center Cincinnati Ohio 45229
University Hospitals of Cleveland, Division of Child & Adolescent Psychiatry Cleveland Ohio 44106
IPS Research Company Oklahoma City Oklahoma 73103
University of Pennsylvania, Department of Psychiatry, Mood & Anxiety Disorders Section Philadelphia Pennsylvania 19104
Drexel University College of Medicine, Friends Hospital Philadelphia Pennsylvania 19124
Clinical Neuroscience Solutions Memphis Tennessee 38119
University of Texas Southwestern Medical Center, Center for Pediatric Psychiatry Dallas Texas 75235
University of Texas Medical Branch, Department of Psychiatry & Behavioral Sciences Galveston Texas 77555
Brighton Research Group, LLC Virginia Beach Virginia 23452
Northwest Clinical Research Center Bellevue Washington 98004

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00107120, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 5, 2012 · Synced Sep 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00107120 live on ClinicalTrials.gov.

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