ClinicalTrials.gov record
Study of Deferasirox Relative to Subcutaneous Deferoxamine in Sickle Cell Disease Patients
ClinicalTrials.gov ID: NCT00110617
Public ClinicalTrials.gov record NCT00110617. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Open-label, Multi-center, Phase II Study to Evaluate the Safety and Efficacy of Deferasirox (ICL670) 20 mg/kg/Day Relative to Subcutaneous Deferoxamine in Sickle Cell Disease Patients With Iron Overload From Repeated Blood Transfusions
Study identification
- NCT ID
- NCT00110617
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 212 participants
Conditions and interventions
Conditions
Interventions
- Deferasirox (ICL670) Drug
- Deferoxamine (DFO) Drug
Drug
Eligibility (public fields only)
- Age range
- 2 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 30, 2005
- Primary completion
- Mar 31, 2008
- Completion
- Mar 31, 2008
- Last update posted
- May 25, 2011
2005 – 2008
United States locations
- U.S. sites
- 56
- U.S. states
- 20
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Pediatric Hematology/Oncology | Birmingham | Alabama | 35233 | — |
| University of Alabama Medical center | Birmingham | Alabama | 35294 | — |
| University of South Alabama Medical Center | Mobile | Alabama | 36604 | — |
| University of South Alabama | Mobile | Alabama | 36617 | — |
| Loma Linda University Medical Center | Loma Linda | California | 92354 | — |
| Children's Hospital Oakland | Oakland | California | 94609 | — |
| Center for Cancer and Blood Disorders | Washington D.C. | District of Columbia | 20010-2970 | — |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010 | — |
| Howard University Hospital | Washington D.C. | District of Columbia | 20059 | — |
| Miami Children's Hospital | Miami | Florida | 33155 | — |
| Tampa Children's Hospital at St Joseph's | Tampa | Florida | 33607-6387 | — |
| Tampa Children's Hospital at St. Joseph's | Tampa | Florida | 33607-6387 | — |
| H. Lee Muffit Cancer Center and Research Institute/James A. Haley Veterans Hospital | Tampa | Florida | 33612 | — |
| Emory University School of Medicine | Atlanta | Georgia | 30303 | — |
| Children's Healthcare of Atlanta at Scottish Rite | Atlanta | Georgia | 30342 | — |
| Adult Sickle Cell Clinic | Augusta | Georgia | 30912-3128 | — |
| Backus Children's Hospital | Savannah | Georgia | 31403 | — |
| University of Illinois at Chicago | Chicago | Illinois | 60612 | — |
| Children's Memorial Hospital | Chicago | Illinois | 60614-3394 | — |
| Pediatric Sickle Cell Program/James Whitcomb Riley Hospital for Children | Indianapolis | Indiana | 46202 | — |
| St. Jude Children's Hospital Affiliate | Baton Rouge | Louisiana | 70808 | — |
| Tulane University Sickle Cell Center | New Orleans | Louisiana | 70112 | — |
| Children's Hospital | New Orleans | Louisiana | 70118 | — |
| LSU Health Sciences Center/Carroll W. Feist Professor of Cancer Research | Shreveport | Louisiana | 71130 | — |
| Brigham and Woman's Hospital/Harvard Medical School | Boston | Massachusetts | 02115 | — |
| Children's Hospital Boston | Boston | Massachusetts | 02115 | — |
| Children's Hospital | Boston | Massachusetts | 02115 | — |
| University of Michigan | Ann Arbor | Michigan | 48109-0238 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| SUNY Downstate Medical Center | Brooklyn | New York | 11203 | — |
| New York Methodist Hospital | Brooklyn | New York | 11215 | — |
| Weill Medical College of Cornell University | New York | New York | 10021 | — |
| Columbia University | New York | New York | 10032 | — |
| Sickle Cell Center, Montefiore Hospital | The Bronx | New York | 10467-2490 | — |
| Carolinas Medical Transplant Center | Charlotte | North Carolina | 28232 | — |
| University of Cincinnati | Cincinnati | Ohio | 45219 | — |
| Children's Hospital Medical Center | Cincinnati | Ohio | 72764 | — |
| The University of Oklahoma | Oklahoma City | Oklahoma | 73104 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104-4399 | — |
| Pennsylvania Oncology/Hematology | Philadelphia | Pennsylvania | 19106 | — |
| Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Drexel University College of Medicine | Philadelphia | Pennsylvania | 19134-1095 | — |
| Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | — |
| Liberty Hematology Oncology Center | Columbia | South Carolina | 29203 | — |
| Palmetto Health Clinical Trials | Columbia | South Carolina | 29203 | — |
| Santee Hematology/Oncology | Sumter | South Carolina | 29150 | — |
| St Jude's Children's Research Hospital | Memphis | Tennessee | 38105-2794 | — |
| St. Jude's Children Research Hospital | Memphis | Tennessee | 38105 | — |
| Cooks Children's Hospital | Fort Worth | Texas | 76104-2724 | — |
| Texas Children's Hospital/Baylor College of Medicine | Houston | Texas | 77030-2399 | — |
| Scott and White Memorial Hospital & Clinics | Temple | Texas | 76508 | — |
| Children's Hospital of the King's Daughter | Norfolk | Virginia | 23507 | — |
| Medical College of Virginia | Richmond | Virginia | 23298-0306 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298-0646 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00110617, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 25, 2011 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00110617 live on ClinicalTrials.gov.