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Completed Phase 2 Interventional

AAB-001 in Patients With Mild to Moderate Alzheimer's Disease

ClinicalTrials.gov ID: NCT00112073

Public ClinicalTrials.gov record NCT00112073. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 12:45 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase IIA, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose, Safety, Tolerability, Pharmacokinetic, Pharmacodynamic, and Immunogenicity Trial of AAB-001 in Patients With Mild to Moderate AD

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to assess the safety and tolerability of multiple doses of AAB-001 passive immunization in patients with mild to moderate Alzheimer's disease (AD).

Study identification

NCT ID
NCT00112073
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
234 participants

Conditions and interventions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
50 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 2005 (Type not available)
Primary completion
Nov 2008 (Actual)
Completion
Dec 2008 (Actual)
Last update posted
Mar 14, 2012

2005 – 2008

United States locations

U.S. sites
26
U.S. states
19
U.S. cities
26
Facility City State ZIP Site status
Cleo Roberts Center for Clinical Research / Sun Health Research Institute Sun City Arizona 85351 —
UC Irvine Irvine California 92697 —
Pharmacology Research Institute Los Alamitos California 90720 —
Pharmacology Research Institute Northridge California 91324 —
UCSD Shiley-Marcos Alzheimer's Disease Research Center San Diego California — —
Memory & Aging Center, UCSF San Francisco California — —
Yale University School of Medicine New Haven Connecticut 06510 —
Georgetown University Medical Center Washington D.C. District of Columbia 20057 —
Brain Matters Research, Inc. Delray Beach Florida 33445 —
Mayo Clinic - Department of Neurology Jacksonville Florida 32224 —
Rush Presbyterian St. Luke's Medical Center Chicago Illinois 60612 —
Department of Neurology - Indiana University Medical Center Indianapolis Indiana 46202 —
Behavioral Neurology Boston Massachusetts 02115 —
University of Michigan Health System, Department of Neurology Ann Arbor Michigan 48109 —
Mayo Clinic Department of Neurology - Alzheimer's Disease Research Center Rochester Minnesota 55905 —
The Memory Enhancement Center Long Branch New Jersey 07740 —
Sergievsky Center, Columbia University New York New York 10032 —
University of Rochester / Monroe Community Hospital Rochester New York 14620 —
Department of Psychiatry and Behavioral Sciences Durham North Carolina 27710 —
Oregon Health and Science University Portland Oregon 97239 —
University of Pittsburgh Pittsburgh Pennsylvania 15213 —
Memory and Aging Program, Butler Hospital Providence Rhode Island 02906 —
University of Texas Southwestern Medical Center Dallas Texas 75390 —
Baylor College of Medicine Houston Texas 77030 —
Clinical Neuroscience Research Associates, Inc. Bennington Vermont 05201 —
University of Washington Seattle Washington 98108 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00112073, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 14, 2012 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00112073 live on ClinicalTrials.gov.

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