Cisplatin and Docetaxel With or Without Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Newly Diagnosed Stage III Non-Small Cell Lung Cancer
Public ClinicalTrials.gov record NCT00113386. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase III Randomized Trial of Preoperative Chemotherapy Versus Preoperative Concurrent Chemotherapy and Thoracic Radiotherapy Followed by Surgical Resection and Consolidation Chemotherapy in Favorable Prognosis Patients With Stage IIIA (N2) Non-Small Cell Lung Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy, such as cisplatin and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Cisplatin and docetaxel may make tumor cells more sensitive to radiation therapy. Giving more than one drug (combination chemotherapy) together with radiation therapy before surgery may shrink the tumor so it can be removed. Giving chemotherapy after surgery may kill any tumor cells that remain after surgery. It is not yet known whether giving cisplatin and docetaxel together with radiation therapy is more effective than giving cisplatin together with docetaxel in treating non-small cell lung cancer. PURPOSE: This randomized phase III trial is studying cisplatin, docetaxel, and radiation therapy to see how well they work compared to cisplatin and docetaxel in treating patients who are undergoing surgery for newly diagnosed stage III non-small cell lung cancer.
Study identification
- NCT ID
- NCT00113386
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 19 participants
Conditions and interventions
Conditions
Interventions
- filgrastim Biological
- pegfilgrastim Biological
- cisplatin Drug
- docetaxel Drug
- adjuvant therapy Procedure
- conventional surgery Procedure
- neoadjuvant therapy Procedure
- radiation therapy Radiation
Biological · Drug · Procedure + 1 more
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2005 (Type not available)
- Primary completion
- Feb 2009 (Actual)
- Completion
- Not listed
- Last update posted
- Jun 28, 2013
Started 2005
United States locations
- U.S. sites
- 76
- U.S. states
- 28
- U.S. cities
- 67
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cancer Center at Providence Alaska Medical Center | Anchorage | Alaska | 99519-6604 | — |
| Arkansas Cancer Research Center at University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Cancer Care Center at John Muir Health - Concord Campus | Concord | California | 94524-4110 | — |
| Moores UCSD Cancer Center | La Jolla | California | 92093-0658 | — |
| USC/Norris Comprehensive Cancer Center and Hospital | Los Angeles | California | 90089-9181 | — |
| University of California Davis Cancer Center | Sacramento | California | 95817 | — |
| Memorial Hospital | Colorado Springs | Colorado | 80909 | — |
| Front Range Cancer Specialists | Fort Collins | Colorado | 80524 | — |
| Poudre Valley Hospital | Fort Collins | Colorado | 80524 | — |
| CCOP - Christiana Care Health Services | Newark | Delaware | 19713 | — |
| Mayo Clinic - Jacksonville | Jacksonville | Florida | 32224 | — |
| Ella Milbank Foshay Cancer Center at Jupiter Medical Center | Jupiter | Florida | 33458 | — |
| Watson Clinic, LLC | Lakeland | Florida | 33804-5000 | — |
| CCOP - Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| Phoebe Cancer Center at Phoebe Putney Memorial Hospital | Albany | Georgia | 31701 | — |
| CCOP - Atlanta Regional | Atlanta | Georgia | 30342 | — |
| Northeast Georgia Medical Center | Gainesville | Georgia | 30501 | — |
| Delnor Community Hospital - Geneva | Geneva | Illinois | 60134 | — |
| Cardinal Bernardin Cancer Center at Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| Community Cancer Center | Normal | Illinois | 61761 | — |
| Advocate Christ Medical Center | Oak Lawn | Illinois | 60453-2699 | — |
| Cancer Treatment Center at Pekin Hospital | Pekin | Illinois | 61554 | — |
| Oncology Hematology Associates of Central Illinois, PC - Peoria | Peoria | Illinois | 61615 | — |
| OSF St. Francis Medical Center | Peoria | Illinois | 61637 | — |
| Cancer Institute at St. John's Hospital | Springfield | Illinois | 62702 | — |
| Reid Hospital & Health Care Services, Incorporated | Richmond | Indiana | 47374 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| Hematology Oncology Associates of the Quad Cities | Bettendorf | Iowa | 52722 | — |
| Genesis Regional Cancer Center at Genesis Medical Center | Davenport | Iowa | 52803 | — |
| Markey Cancer Center at University of Kentucky Chandler Medical Center | Lexington | Kentucky | 40536-0293 | — |
| St. Agnes Hospital Cancer Center | Baltimore | Maryland | 21229 | — |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | 21231-2410 | — |
| Frederick Memorial Hospital Regional Cancer Therapy Center | Frederick | Maryland | 21701 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| CCOP - Michigan Cancer Research Consortium | Ann Arbor | Michigan | 48106 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109-0942 | — |
| Bronson Methodist Hospital | Kalamazoo | Michigan | 49007 | — |
| Upper Michigan Cancer Center at Marquette General Hospital | Marquette | Michigan | 49855 | — |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | — |
| St. John's Regional Medical Center | Joplin | Missouri | 64804 | — |
| St. John's Regional Health Center | Springfield | Missouri | 65804 | — |
| Siteman Cancer Center at Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| Good Samaritan Cancer Center at Good Samaritan Hospital | Kearney | Nebraska | 68848-1990 | — |
| Methodist Cancer Center at Methodist Hospital - Omaha | Omaha | Nebraska | 68114 | — |
| UNMC Eppley Cancer Center at the University of Nebraska Medical Center | Omaha | Nebraska | 68198-6805 | — |
| Valley Hospital - Ridgewood | Ridgewood | New Jersey | 07450 | — |
| NYU Cancer Institute at New York University Medical Center | New York | New York | 10016 | — |
| SUNY Upstate Medical University Hospital | Syracuse | New York | 13210 | — |
| Faxton Regional Cancer Center | Utica | New York | 13502 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| Leo W. Jenkins Cancer Center at ECU Medical School | Greenville | North Carolina | 27835-6028 | — |
| Lenoir Memorial Cancer Center | Kinston | North Carolina | 28501 | — |
| FirstHealth Moore Regional Community Hospital Comprehensive Cancer Center | Pinehurst | North Carolina | 28374 | — |
| Charles M. Barrett Cancer Center at University Hospital | Cincinnati | Ohio | 45267 | — |
| Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University | Columbus | Ohio | 43210-1240 | — |
| Veterans Affairs Medical Center - Portland | Portland | Oregon | 97207 | — |
| Oregon Health & Science University Cancer Institute | Portland | Oregon | 97239-3098 | — |
| St. Luke's Hospital Cancer Center | Bethlehem | Pennsylvania | 18015 | — |
| Penn State Cancer Institute at Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| Lancaster General Hospital | Lancaster | Pennsylvania | 17604 | — |
| Kimmel Cancer Center at Thomas Jefferson University - Philadelphia | Philadelphia | Pennsylvania | 19107-5541 | — |
| Albert Einstein Cancer Center | Philadelphia | Pennsylvania | 19141 | — |
| Allegheny Cancer Center at Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| York Cancer Center at Apple Hill Medical Center | York | Pennsylvania | 17405 | — |
| Hollings Cancer Center at Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| CCOP - Greenville | Greenville | South Carolina | 29615 | — |
| CCOP - Upstate Carolina | Spartanburg | South Carolina | 29303 | — |
| U.T. Cancer Institute at University of Tennessee Medical Center | Knoxville | Tennessee | 37920-6999 | — |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | — |
| Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas | Dallas | Texas | 75390 | — |
| CCOP - Virginia Mason Research Center | Seattle | Washington | 98101 | — |
| Swedish Cancer Institute at Swedish Medical Center - First Hill Campus | Seattle | Washington | 98122-4307 | — |
| Madigan Army Medical Center - Tacoma | Tacoma | Washington | 98431 | — |
| Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center | Green Bay | Wisconsin | 54311 | — |
| Dean Medical Center - Madison | Madison | Wisconsin | 53717 | — |
| Vince Lombardi Cancer Clinic - Sheboygan | Sheboygan | Wisconsin | 53081 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00113386, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 28, 2013 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00113386 live on ClinicalTrials.gov.