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Completed Phase 2 Interventional Results available

Topotecan in Treating Patients With Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer

ClinicalTrials.gov ID: NCT00114166

Public ClinicalTrials.gov record NCT00114166. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 25, 2026, 12:17 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Phase II Evaluation of Topotecan (NSC #609699) Administered Daily x 5 Every 3 Weeks vs Weekly Topotecan in the Treatment of Recurrent Platinum-Sensitive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Drugs used in chemotherapy, such as topotecan, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving topotecan in different dosing schedules may kill more tumor cells. PURPOSE: This phase II trial is studying how well topotecan works in treating patients with recurrent ovarian epithelial, fallopian tube, or primary peritoneal cancer.

Study identification

NCT ID
NCT00114166
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Gynecologic Oncology Group
Network
Enrollment
81 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 120 Years
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 31, 2004
Primary completion
Dec 31, 2010
Completion
Not listed
Last update posted
Jul 23, 2018

Started 2005

United States locations

U.S. sites
78
U.S. states
23
U.S. cities
63
Facility City State ZIP Site status
Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center Hartford Connecticut 06105 —
George Bray Cancer Center at the Hospital of Central Connecticut - New Britain Campus New Britain Connecticut 06050 —
Tunnell Cancer Center at Beebe Medical Center Lewes Delaware 19958 —
CCOP - Christiana Care Health Services Newark Delaware 19713 —
Washington Cancer Institute at Washington Hospital Center Washington D.C. District of Columbia 20010 —
MBCCOP - Medical College of Georgia Cancer Center Augusta Georgia 30912 —
Rush-Copley Cancer Care Center Aurora Illinois 60507 —
University of Illinois Cancer Center Chicago Illinois 60612-7243 —
Rush University Medical Center Chicago Illinois 60612 —
Hinsdale Hematology Oncology Associates Hinsdale Illinois 60521 —
Joliet Oncology-Hematology Associates, Limited - West Joliet Illinois 60435 —
Advocate Lutheran General Cancer Care Center Park Ridge Illinois 60068-1174 —
Carle Cancer Center at Carle Foundation Hospital Urbana Illinois 61801 —
CCOP - Carle Cancer Center Urbana Illinois 61801 —
Saint Anthony Memorial Health Centers Michigan City Indiana 46360 —
Holden Comprehensive Cancer Center at University of Iowa Iowa City Iowa 52242-1002 —
Woman's Hospital Baton Rouge Louisiana 70815 —
Union Hospital Cancer Program at Union Hospital Elkton Maryland 21921 —
Tufts-NEMC Cancer Center Boston Massachusetts 02111 —
UMASS Memorial Cancer Center - University Campus Worcester Massachusetts 01655 —
Saint Joseph Mercy Cancer Center Ann Arbor Michigan 48106-0995 —
CCOP - Michigan Cancer Research Consortium Ann Arbor Michigan 48106 —
Oakwood Cancer Center at Oakwood Hospital and Medical Center Dearborn Michigan 48123-2500 —
Genesys Hurley Cancer Institute Flint Michigan 48503 —
Hurley Medical Center Flint Michigan 48503 —
Van Elslander Cancer Center at St. John Hospital and Medical Center Grosse Pointe Woods Michigan 48236 —
Foote Memorial Hospital Jackson Michigan 49201 —
Borgess Medical Center Kalamazoo Michigan 49001 —
West Michigan Cancer Center Kalamazoo Michigan 49007-3731 —
Bronson Methodist Hospital Kalamazoo Michigan 49007 —
Sparrow Regional Cancer Center Lansing Michigan 48912-1811 —
St. Mary Mercy Hospital Livonia Michigan 48154 —
St. Joseph Mercy Oakland Pontiac Michigan 48341-2985 —
Mercy Regional Cancer Center at Mercy Hospital Port Huron Michigan 48060 —
William Beaumont Hospital - Royal Oak Campus Royal Oak Michigan 48073 —
Seton Cancer Institute at Saint Mary's - Saginaw Saginaw Michigan 48601 —
St. John Macomb Hospital Warren Michigan 48093 —
University of Mississippi Cancer Clinic Jackson Mississippi 39216 —
CCOP - Cancer Research for the Ozarks Springfield Missouri 65802 —
St. John's Regional Health Center Springfield Missouri 65804 —
Hulston Cancer Center at Cox Medical Center South Springfield Missouri 65807 —
Saint Louis University Cancer Center St Louis Missouri 63110 —
Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis St Louis Missouri 63110 —
Cancer Resource Center - Lincoln Lincoln Nebraska 68510 —
CCOP - Missouri Valley Cancer Consortium Omaha Nebraska 68106 —
Methodist Estabrook Cancer Center Omaha Nebraska 68114 —
Jersey Shore Cancer Center at Jersey Shore University Medical Center Neptune City New Jersey 07754-0397 —
Cancer Institute of New Jersey at Cooper - Voorhees Voorhees Township New Jersey 08043 —
SUNY Downstate Medical Center Brooklyn New York 11203 —
Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center New York New York 10032 —
Stony Brook University Cancer Center Stony Brook New York 11794-9446 —
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill Chapel Hill North Carolina 27599-7295 —
Blumenthal Cancer Center at Carolinas Medical Center Charlotte North Carolina 28232-2861 —
Wake Forest University Comprehensive Cancer Center Winston-Salem North Carolina 27157-1096 —
McDowell Cancer Center at Akron General Medical Center Akron Ohio 44307 —
Case Comprehensive Cancer Center Cleveland Ohio 44106-5065 —
Cleveland Clinic Cancer Center at Fairview Hospital Cleveland Ohio 44111 —
Cleveland Clinic Taussig Cancer Center Cleveland Ohio 44195 —
Riverside Methodist Hospital Cancer Care Columbus Ohio 43214-3998 —
Mount Carmel Health - West Hospital Columbus Ohio 43222 —
Hillcrest Cancer Center at Hillcrest Hospital Mayfield Heights Ohio 44124 —
Lake/University Ireland Cancer Center Mentor Ohio 44060 —
Oklahoma University Cancer Institute Oklahoma City Oklahoma 73104 —
Cancer Care Associates - Midtown Tulsa Tulsa Oklahoma 74104 —
Rosenfeld Cancer Center at Abington Memorial Hospital Abington Pennsylvania 19001 —
Bryn Mawr Hospital Bryn Mawr Pennsylvania 19010 —
Penn State Cancer Institute at Milton S. Hershey Medical Center Hershey Pennsylvania 17033-0850 —
Cancer Center of Paoli Memorial Hospital Paoli Pennsylvania 19301-1792 —
Fox Chase Cancer Center - Philadelphia Philadelphia Pennsylvania 19111-2497 —
McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center Reading Pennsylvania 19612-6052 —
CCOP - MainLine Health Wynnewood Pennsylvania 19096 —
Lankenau Cancer Center at Lankenau Hospital Wynnewood Pennsylvania 19096 —
Avera Cancer Institute Sioux Falls South Dakota 57105 —
Sanford Cancer Center at Sanford USD Medical Center Sioux Falls South Dakota 57117-5039 —
Harrington Cancer Center Amarillo Texas 79106 —
Marshfield Clinic - Marshfield Center Marshfield Wisconsin 54449 —
Marshfield Clinic - Indianhead Center Rice Lake Wisconsin 54868 —
Marshfield Clinic - Weston Center Weston Wisconsin 54476 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00114166, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 23, 2018 · Synced Sep 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00114166 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →