Capecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Stage I Rectal Cancer
Public ClinicalTrials.gov record NCT00114231. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Trial of Chemoradiotherapy and Local Excision for uT2uN0 Rectal Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy, such as capecitabine and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Oxaliplatin may make tumor cells more sensitive to radiation therapy. Giving capecitabine and oxaliplatin together with radiation therapy before surgery may shrink the tumor so it can be removed. PURPOSE: This phase II trial is studying how well giving capecitabine and oxaliplatin together with radiation therapy works in treating patients who are undergoing surgery for stage I rectal cancer.
Study identification
- NCT ID
- NCT00114231
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 90 participants
Conditions and interventions
Conditions
Interventions
- capecitabine Drug
- oxaliplatin Drug
- neoadjuvant therapy Procedure
- radiation therapy Radiation
Drug · Procedure · Radiation
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2006 (Type not available)
- Primary completion
- Dec 2013 (Actual)
- Completion
- Dec 2014 (Actual)
- Last update posted
- Mar 29, 2018
2006 – 2014
United States locations
- U.S. sites
- 67
- U.S. states
- 20
- U.S. cities
- 49
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Scottsdale | Scottsdale | Arizona | 85259-5499 | — |
| Cancer Care Center at John Muir Health - Concord Campus | Concord | California | 94524-4110 | — |
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010-3000 | — |
| USC/Norris Comprehensive Cancer Center and Hospital | Los Angeles | California | 90089-9181 | — |
| Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center | Orange | California | 92868 | — |
| John Muir/Mt. Diablo Comprehensive Cancer Center | Walnut Creek | California | 94598 | — |
| St. Vincent's Medical Center | Bridgeport | Connecticut | 06606 | — |
| Praxair Cancer Center at Danbury Hospital | Danbury | Connecticut | 06810 | — |
| Mayo Clinic - Jacksonville | Jacksonville | Florida | 32224 | — |
| Tampa General Hospital | Tampa | Florida | 33606 | — |
| Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center | Savannah | Georgia | 31403-3089 | — |
| Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler | Savannah | Georgia | 31405 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637-1470 | — |
| St. Francis Hospital and Health Centers - Beech Grove Campus | Beech Grove | Indiana | 46107 | — |
| Indiana University Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202-5289 | — |
| William N. Wishard Memorial Hospital | Indianapolis | Indiana | 46202 | — |
| Reid Hospital & Health Care Services | Richmond | Indiana | 47374 | — |
| Ochsner Cancer Institute at Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | — |
| Altru Cancer Center at Altru Hospital | Grand Forks | North Dakota | 58201 | — |
| Grandview Hospital | Dayton | Ohio | 45405 | — |
| Good Samaritan Hospital | Dayton | Ohio | 45406 | — |
| David L. Rike Cancer Center at Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| Samaritan North Cancer Care Center | Dayton | Ohio | 45415 | — |
| Veterans Affairs Medical Center - Dayton | Dayton | Ohio | 45428 | — |
| CCOP - Dayton | Dayton | Ohio | 45429 | — |
| Blanchard Valley Medical Associates | Findlay | Ohio | 45840 | — |
| Middletown Regional Hospital | Franklin | Ohio | 45005-1066 | — |
| Wayne Hospital | Greenville | Ohio | 45331 | — |
| Charles F. Kettering Memorial Hospital | Kettering | Ohio | 45429 | — |
| UVMC Cancer Care Center at Upper Valley Medical Center | Troy | Ohio | 45373-1300 | — |
| Clinton Memorial Hospital | Wilmington | Ohio | 45177 | — |
| Ruth G. McMillan Cancer Center at Greene Memorial Hospital | Xenia | Ohio | 45385 | — |
| Integris Oncology Services | Oklahoma City | Oklahoma | 73112 | — |
| Natalie Warren Bryant Cancer Center at St. Francis Hospital | Tulsa | Oklahoma | 74136 | — |
| Providence Cancer Center at Providence Portland Medical Center | Portland | Oregon | 97213-2967 | — |
| Knight Cancer Institute at Oregon Health and Science University | Portland | Oregon | 97239-3098 | — |
| Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest | Allentown | Pennsylvania | 18105 | — |
| UPMC Cancer Center at Beaver Medical Center | Beaver | Pennsylvania | 15009 | — |
| UPMC Cancer Center at Jefferson Regional Medical Center | Clairton | Pennsylvania | 15025 | — |
| UPMC Cancer Center - Arnold Palmer Pavilion | Greensburg | Pennsylvania | 15601 | — |
| Penn State Cancer Institute at Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| UPMC Cancer Center at the John P. Murtha Pavilion | Johnstown | Pennsylvania | 15901 | — |
| UPMC - Moon | Moon Township | Pennsylvania | 15108 | — |
| UPMC Cancer Center - Natrona Heights | Natrona Heights | Pennsylvania | 15065 | — |
| Jameson Memorial Hospital - North Campus | New Castle | Pennsylvania | 16105 | — |
| Fox Chase Cancer Center - Philadelphia | Philadelphia | Pennsylvania | 19111-2497 | — |
| Allegheny Cancer Center at Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| UPMC - Shadyside | Pittsburgh | Pennsylvania | 15213-2582 | — |
| UPMC Cancer Center at Magee-Womens Hospital | Pittsburgh | Pennsylvania | 15213 | — |
| UPMC Cancer Center at UPMC Presbyterian | Pittsburgh | Pennsylvania | 15213 | — |
| UPMC Cancer Center at UPMC St. Margaret | Pittsburgh | Pennsylvania | 15215 | — |
| Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital | Pittsburgh | Pennsylvania | 15224-1791 | — |
| UPMC Cancer Centers | Pittsburgh | Pennsylvania | 15232 | — |
| UPMC Cancer Center at UPMC Passavant | Pittsburgh | Pennsylvania | 15237 | — |
| St. Clair Memorial Hospital Cancer Center | Pittsburgh | Pennsylvania | 15243 | — |
| UPMC Cancer Center at UPMC Northwest | Seneca | Pennsylvania | 16346 | — |
| Washington Hospital Cancer Center | Washington | Pennsylvania | 15301 | — |
| Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | 37232-6838 | — |
| M. D. Anderson Cancer Center at University of Texas | Houston | Texas | 77030-4009 | — |
| Methodist Hospital | Houston | Texas | 77030 | — |
| Surgical Oncology Associates | Newport News | Virginia | 23606 | — |
| Providence Cancer Center at Sacred Heart Medical Center | Spokane | Washington | 99204 | — |
| Providence Cancer Center at Holy Family Hospital | Spokane | Washington | 99207 | — |
| United Hospital Center | Clarksburg | West Virginia | 26301 | — |
| Edwards Comprehensive Cancer Center at Cabell Huntington Hospital | Huntington | West Virginia | 25701 | — |
| University of Wisconsin Paul P. Carbone Comprehensive Cancer Center | Madison | Wisconsin | 53792-6164 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00114231, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 29, 2018 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00114231 live on ClinicalTrials.gov.