Safety Study of Adult Mesenchymal Stem Cells (MSC) to Treat Acute Myocardial Infarction
Public ClinicalTrials.gov record NCT00114452. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1 Randomized, Double-blind, Placebo-controlled, Dose Escalation, Multicenter Study to Determine the Safety of Intravenous Ex-vivo Cultured Adult Human Mesenchymal Stem Cells (Provacel) Following Acute Myocardial Infarction
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to determine whether adult stem cells \[Provacel™(PUMP1)\] are safe and possibly effective in the treatment of acute myocardial infarction (heart attack).
Study identification
- NCT ID
- NCT00114452
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 60 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 21 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 22, 2005 (Actual)
- Primary completion
- Oct 4, 2006 (Actual)
- Completion
- Apr 24, 2008 (Actual)
- Last update posted
- Mar 10, 2020
2005 – 2008
United States locations
- U.S. sites
- 15
- U.S. states
- 12
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Heart Institute | Phoenix | Arizona | 85006 | — |
| University of California - San Diego; Thornton | San Diego | California | 92103-8411 | — |
| Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| The Care Group | Indianapolis | Indiana | 46260 | — |
| Jewish Hospital | Louisville | Kentucky | 40202 | — |
| Johns Hopkins University | Baltimore | Maryland | 21205 | — |
| Washington Adventist | Takoma Park | Maryland | 20912 | — |
| Minneapolis Heart Institute | Minneapolis | Minnesota | 55407 | — |
| Columbia Presbyterian Hospital | New York | New York | 10032 | — |
| University of Rochester - Strong Memorial | Rochester | New York | 14642 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| University of Pennsylvania Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| Austin Heart Institute | Austin | Texas | 78756 | — |
| Texas Medical School | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00114452, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 10, 2020 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00114452 live on ClinicalTrials.gov.