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Completed Phase 3 Interventional Results available

A Study to Compare Tenofovir Disoproxil Fumarate Versus Adefovir Dipivoxil for the Treatment of HBeAg-Negative Chronic Hepatitis B

ClinicalTrials.gov ID: NCT00117676

Public ClinicalTrials.gov record NCT00117676. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 26, 2026, 2:30 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Controlled Evaluation of Tenofovir DF Versus Adefovir Dipivoxil for the Treatment of Presumed Pre-Core Mutant Chronic Hepatitis B

Study identification

NCT ID
NCT00117676
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Gilead Sciences
Industry
Enrollment
382 participants

Conditions and interventions

Interventions

  • TDF Drug
  • ADV Drug
  • TDF placebo Drug
  • ADV placebo Drug
  • FTC/TDF Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 69 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 31, 2005
Primary completion
Mar 31, 2007
Completion
Dec 31, 2015
Last update posted
Mar 6, 2017

2005 – 2016

United States locations

U.S. sites
17
U.S. states
8
U.S. cities
15
Facility City State ZIP Site status
Not listed La Jolla California 92037
Not listed Pasadena California 91105
Not listed San Diego California 92105
Not listed San Diego California 92123
Not listed San Francisco California 94115
Not listed San Jose California 95116
Not listed Atlanta Georgia 30308
Not listed Honolulu Hawaii 96817
Not listed Boston Massachusetts 02215
Not listed Ann Arbor Michigan 48109
Not listed Detroit Michigan 48202
Not listed St Louis Missouri 63104
Not listed Flushing New York 11355
Not listed New York New York 10003
Not listed New York New York 10029
Not listed Falls Church Virginia 22042
Not listed Richmond Virginia 23298

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 63 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00117676, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 6, 2017 · Synced Jun 26, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00117676 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →