Efavirenz or Atazanavir/Ritonavir Given With Emtricitabine/Tenofovir Disoproxil Fumarate or Abacavir/Lamivudine in HIV Infected Treatment-Naive Adults
Public ClinicalTrials.gov record NCT00118898. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase IIIB, Randomized Trial of Open-Label Efavirenz or Atazanavir With Ritonavir in Combination With Double-Blind Comparison of Emtricitabine/Tenofovir or Abacavir/Lamivudine in Antiretroviral-Naive Subjects
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Currently, the preferred anti-HIV regimens used in the United States consist of two nucleoside reverse transcriptase inhibitors (NRTIs) and the nonnucleoside reverse transcriptase inhibitor (NNRTI) efavirenz (EFV). However, with new anti-HIV drugs being approved, alternative regimens need to be tested to determine if new drug combinations have increased effectiveness in treating HIV. The purpose of this study is to test the safety, tolerability, and effectiveness of four different regimens in HIV-infected adults who have never taken anti-HIV drugs.
Study identification
- NCT ID
- NCT00118898
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,864 participants
Conditions and interventions
Conditions
Interventions
- Abacavir/Lamivudine Drug
- Atazanavir Drug
- Efavirenz Drug
- Emtricitabine/Tenofovir disoproxil fumarate Drug
- Ritonavir Drug
- Abacavir/Lamivudine placebo Drug
- Emtricitabine/Tenofovir disoproxil fumarate placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 16 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2005 (Type not available)
- Primary completion
- Nov 2009 (Actual)
- Completion
- Nov 2009 (Actual)
- Last update posted
- Oct 12, 2018
2005 – 2009
United States locations
- U.S. sites
- 51
- U.S. states
- 19
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Usc Crs (1201) | Los Angeles | California | 90033 | — |
| UCLA CARE Center CRS (601) | Los Angeles | California | 90035 | — |
| Stanford CRS (501) | Palo Alto | California | 94304 | — |
| Ucsd, Avrc Crs (701) | San Diego | California | 92103 | — |
| Ucsf Aids Crs (801) | San Francisco | California | 94110 | — |
| San Mateo County AIDS Program (505) | Stanford | California | 94305-5107 | — |
| Willow Clinic (507) | Stanford | California | 94305-5107 | — |
| Harbor-UCLA Med. Ctr. CRS (603) | Torrance | California | 90502 | — |
| University of Colorado Hospital CRS (6101) | Aurora | Colorado | 80045 | — |
| Georgetown University CRS (GU CRS) (1008) | Washington D.C. | District of Columbia | 20007 | — |
| University of Miami AIDS CRS (901) | Miami | Florida | 33139 | — |
| Emory University | Atlanta | Georgia | 30308 | — |
| The Ponce de Leon Center CRS (5802) | Atlanta | Georgia | 30308 | — |
| Northwestern University CRS (2701) | Chicago | Illinois | 60611 | — |
| Cook County Hospital Core Center (2705) | Chicago | Illinois | 60612 | — |
| Rush Univ. Med. Ctr. ACTG CRS (2702) | Chicago | Illinois | 60612 | — |
| Indiana University Hospital (2601) | Indianapolis | Indiana | 46202-5250 | — |
| Wishard Hospital (2603) | Indianapolis | Indiana | 46202 | — |
| Univ of Iowa Hosp and Clinic (1504) | Iowa City | Iowa | 52242 | — |
| IHV Baltimore Treatment CRS (4651) | Baltimore | Maryland | 21201 | — |
| Johns Hopkins Adult AIDS CRS (201) | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital ACTG CRS (101) | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hosp. ACTG CRS (107) | Boston | Massachusetts | 02115 | — |
| Bmc Actg Crs (104) | Boston | Massachusetts | 02118 | — |
| Beth Israel Deaconess Med. Ctr., ACTG CRS (103) | Boston | Massachusetts | 02215 | — |
| Washington U CRS (2101) | St Louis | Missouri | 63110 | — |
| SUNY - Buffalo (Rochester) (1102) | Buffalo | New York | 14215 | — |
| Cornell CRS (7804) | New York | New York | 10011 | — |
| Weill Med. College of Cornell Univ., The Cornell CTU -Chelsea (7803) | New York | New York | 10011 | — |
| NY Univ. HIV/AIDS CRS (401) | New York | New York | 10016 | — |
| HIV Prevention & Treatment CRS (30329) | New York | New York | 10032 | — |
| Harlem ACTG CRS (31483) | New York | New York | 10037 | — |
| AIDS Community Health Ctr. ACTG CRS (1108) | Rochester | New York | 14604 | — |
| University of Rochester ACTG CRS (1101) | Rochester | New York | 14642 | — |
| Unc Aids Crs (3201) | Chapel Hill | North Carolina | 27514 | — |
| Wake County Department of Health (30076) | Chapel Hill | North Carolina | 27514 | — |
| Duke University Medical Center Adult CRS (1601) | Durham | North Carolina | 27710 | — |
| Moses H. Cone Memorial Hospital CRS (3203) | Greensboro | North Carolina | 27401 | — |
| University of Cincinnati CRS (2401) | Cincinnati | Ohio | 45267 | — |
| Case CRS (2501) | Cleveland | Ohio | 44106 | — |
| Metro Health CRS (2503) | Cleveland | Ohio | 44109 | — |
| The Ohio State Univ. AIDS CRS (2301) | Columbus | Ohio | 43210 | — |
| Presbyterian Medical Center - Univ. of PA (6206) | Norristown | Pennsylvania | 19401 | — |
| Hosp. of the Univ. of Pennsylvania CRS (6201) | Philadelphia | Pennsylvania | 19104 | — |
| Pitt CRS (1001) | Pittsburgh | Pennsylvania | 15213 | — |
| The Miriam Hosp. ACTG CRS (2951) | Providence | Rhode Island | 02906 | — |
| Vanderbilt Therapeutics CRS (3652) | Nashville | Tennessee | 37232 | — |
| Peabody Health Center CRS (31443) | Dallas | Texas | 75215 | — |
| University of Texas, Galveston (6301) | Galveston | Texas | 77555-0435 | — |
| University of Washington AIDS CRS (1401) | Seattle | Washington | 98104 | — |
| University of Washington General Clinical Research (1403) | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00118898, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 12, 2018 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00118898 live on ClinicalTrials.gov.