Kidney Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Rapamune (Sirolimus) in Kidney Transplant Recipients
Public ClinicalTrials.gov record NCT00121810. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open Label, Randomized, Multicenter Study to Evaluate the Efficacy and Safety of Early Calcineurin Inhibitor Withdrawal in Recipients of Primary Renal Allografts Maintained Long-term on Mycophenolate Mofetil (MMF) (CellCept®) and Sirolimus (Rapamune®)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This 2-arm study recruited kidney transplant patients who were receiving standard care of calcineurin inhibitors (CNIs, tacrolimus or cyclosporine), CellCept (1.0-1.5 g twice daily) and corticosteroids. They were either randomized to continue this regimen, or CNI therapy was discontinued and replaced by sirolimus therapy (in combination with CellCept and corticosteroids). The effect of these 2 regimens on efficacy, safety and kidney function was evaluated. The anticipated time on study treatment was 1-2 years, and the target sample size was 100-500 individuals.
Study identification
- NCT ID
- NCT00121810
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 305 participants
Conditions and interventions
Conditions
Interventions
- mycophenolate mofetil [CellCept] Drug
- Corticosteroids Drug
- Calcineurin inhibitors Drug
- Sirolimus Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2003 (Type not available)
- Primary completion
- Nov 2009 (Actual)
- Completion
- Nov 2009 (Actual)
- Last update posted
- Apr 15, 2011
2003 – 2009
United States locations
- U.S. sites
- 36
- U.S. states
- 24
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Bakersfield | California | 93309 | — |
| Not listed | Los Angeles | California | 90033 | — |
| Not listed | Los Angeles | California | 90057 | — |
| Not listed | Palo Alto | California | 94304-1509 | — |
| Not listed | Riverside | California | 92501 | — |
| Not listed | San Diego | California | 92123 | — |
| Not listed | San Francisco | California | 94115 | — |
| Not listed | Denver | Colorado | 80262 | — |
| Not listed | Hartford | Connecticut | 06106-3316 | — |
| Not listed | Washington D.C. | District of Columbia | 20010-2975 | — |
| Not listed | Atlanta | Georgia | 30322 | — |
| Not listed | Maywood | Illinois | 60153 | — |
| Not listed | Indianapolis | Indiana | 46202-5124 | — |
| Not listed | Indianapolis | Indiana | 46202 | — |
| Not listed | Iowa City | Iowa | 52242 | — |
| Not listed | Lexington | Kentucky | 40536-0293 | — |
| Not listed | New Orleans | Louisiana | 70112 | — |
| Not listed | Baltimore | Maryland | 21201 | — |
| Not listed | Boston | Massachusetts | 02114-2696 | — |
| Not listed | Detroit | Michigan | 48202-2689 | — |
| Not listed | Camden | New Jersey | 08103 | — |
| Not listed | Livingston | New Jersey | 07039 | — |
| Not listed | New York | New York | 10029 | — |
| Not listed | New York | New York | 10032 | — |
| Not listed | Durham | North Carolina | 27710 | — |
| Not listed | Cincinnati | Ohio | 45267-0558 | — |
| Not listed | Portland | Oregon | 97201 | — |
| Not listed | Philadelphia | Pennsylvania | 19107 | — |
| Not listed | Charleston | South Carolina | 29425 | — |
| Not listed | Sioux Falls | South Dakota | 57105 | — |
| Not listed | Memphis | Tennessee | 38104 | — |
| Not listed | Nashville | Tennessee | 37232 | — |
| Not listed | Dallas | Texas | 75246 | — |
| Not listed | Galveston | Texas | 77555 | — |
| Not listed | San Antonio | Texas | 78284 | — |
| Not listed | Charlottesville | Virginia | 22908 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00121810, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 15, 2011 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00121810 live on ClinicalTrials.gov.