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Completed Phase 3 Interventional Results available

Extension Study of Eculizumab in Patients With Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH)

ClinicalTrials.gov ID: NCT00122317

Public ClinicalTrials.gov record NCT00122317. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 2:18 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Open Label Extension Study of Eculizumab in Patients With Transfusion Dependent PNH

Study identification

NCT ID
NCT00122317
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Alexion Pharmaceuticals, Inc.
Industry
Enrollment
187 participants

Conditions and interventions

Interventions

  • eculizumab Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2005
Primary completion
Aug 31, 2008
Completion
Sep 30, 2008
Last update posted
Mar 12, 2018

2005 – 2008

United States locations

U.S. sites
14
U.S. states
12
U.S. cities
13
Facility City State ZIP Site status
Stanford University Medical Center, Division of Hematology Stanford California 94305
Hartford Hospital, Cancer Clinical Research Office Hartford Connecticut 06102
Cleveland Clinic Florida, Department of Clinical Research Weston Florida 33331
Indianapolis University Cancer Center Indianapolis Indiana 46202
Johns Hopkins University Medical Center Baltimore Maryland 21205
National Heart, Lung, and Blood Institute, National Institutes of Health Bethesda Maryland 20892
Massachusetts General Hospital Boston Massachusetts 02114
Mayo Clinic, Divison of Hematology Rochester Minnesota 55902
Washington University, Department of Internal Medicine/Division of Hematology St Louis Missouri 63110
NYU Clinical Cancer Center New York New York 10016
Memorial Sloan Kettering Cancer Center New York New York 10017
Duke University Medical Center, Division Cell Therapy, Heme Malignancies Program Durham North Carolina 27710
Cleveland Clinic Foundation Cleveland Ohio 44195
Presbyterian Medical Center, PENN Comprehensive Hemophilia & Thombosis Program Philadelphia Pennsylvania 19104

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 26 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00122317, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 12, 2018 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00122317 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →