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Completed Phase 3 Interventional Accepts healthy volunteers Results available

Human Papilloma Virus (HPV) Vaccine Efficacy Trial Against Cervical Pre-cancer in Young Adults With GlaxoSmithKline (GSK) Biologicals HPV-16/18

ClinicalTrials.gov ID: NCT00122681

Public ClinicalTrials.gov record NCT00122681. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 5:02 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Double-blind, Randomized, Controlled, Multi-center Study to Evaluate the Efficacy of GlaxoSmithKline Biologicals. HPV-16/18 VLP AS04 Vaccine Compared to Hepatitis A Vaccine as Control in Prevention of Persistent HPV-16 or HPV-18 Cervical Infection and Cervical Neoplasia, Administered Intramuscularly According to a 0, 1, 6 Month Schedule in Healthy Females 15-25 Years of Age.

Study identification

NCT ID
NCT00122681
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
GlaxoSmithKline
Industry
Enrollment
18,729 participants

Conditions and interventions

Interventions

  • Cervarix™ Biological
  • Havrix™-based investigational formulation Biological

Biological

Eligibility (public fields only)

Age range
15 Years to 25 Years
Sex
Female
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 5, 2004
Primary completion
Nov 2, 2006
Completion
Nov 25, 2009
Last update posted
Aug 19, 2018

2004 – 2009

United States locations

U.S. sites
50
U.S. states
24
U.S. cities
42
Facility City State ZIP Site status
GSK Investigational Site Birmingham Alabama 35233
GSK Investigational Site Fountain Valley California 92708
GSK Investigational Site San Diego California 92108
GSK Investigational Site San Francisco California 94115
GSK Investigational Site Boulder Colorado 80303
GSK Investigational Site Boulder Colorado 80304
GSK Investigational Site Denver Colorado 80218
GSK Investigational Site Louisville Colorado 80027
GSK Investigational Site Clearwater Florida 33759
GSK Investigational Site Coral Gables Florida 33134
GSK Investigational Site Miami Florida 33136
GSK Investigational Site West Palm Beach Florida 33409
GSK Investigational Site Augusta Georgia 30912
GSK Investigational Site Honolulu Hawaii 96826
GSK Investigational Site Iowa City Iowa 52242
GSK Investigational Site Arkansas City Kansas 67005
GSK Investigational Site Wichita Kansas 67205
GSK Investigational Site Wichita Kansas 67207
GSK Investigational Site Bardstown Kentucky 40004
GSK Investigational Site Louisville Kentucky 40202
GSK Investigational Site Minneapolis Minnesota 55455
GSK Investigational Site Omaha Nebraska 68131
GSK Investigational Site Lebanon New Hampshire 03756
GSK Investigational Site Morristown New Jersey 07960
GSK Investigational Site Albuquerque New Mexico 87131
GSK Investigational Site New York New York 10029
GSK Investigational Site Poughkeepsie New York 12601
GSK Investigational Site Chapel Hill North Carolina 27514
GSK Investigational Site New Bern North Carolina 28562
GSK Investigational Site Cleveland Ohio 44109
GSK Investigational Site Tulsa Oklahoma 74105
GSK Investigational Site Portland Oregon 97210
GSK Investigational Site Carnegie Pennsylvania 15106
GSK Investigational Site Erie Pennsylvania 16502
GSK Investigational Site Erie Pennsylvania 16505
GSK Investigational Site Erie Pennsylvania 16507
GSK Investigational Site Erie Pennsylvania 16508
GSK Investigational Site Philadelphia Pennsylvania 19107
GSK Investigational Site Philadelphia Pennsylvania 19114
GSK Investigational Site Pittsburgh Pennsylvania 15236
GSK Investigational Site Austin Texas 78705
GSK Investigational Site Houston Texas 77004
GSK Investigational Site Houston Texas 77030
GSK Investigational Site Webster Texas 77598
GSK Investigational Site Salt Lake City Utah 84120
GSK Investigational Site Charlottesville Virginia 22903
GSK Investigational Site Spokane Washington 99202
GSK Investigational Site Spokane Washington 99218
GSK Investigational Site Vancouver Washington 98664
GSK Investigational Site Wenatchee Washington 98801

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 88 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00122681, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 19, 2018 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00122681 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →