Stroke With Transfusions Changing to Hydroxyurea
Public ClinicalTrials.gov record NCT00122980. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare standard therapy (transfusions and chelation) with alternative therapy (hydroxyurea and phlebotomy) for the prevention of secondary stroke and management of iron overload in children with sickle cell anemia (SCA).
Study identification
- NCT ID
- NCT00122980
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 134 participants
Conditions and interventions
Interventions
- Red Cell Transfusions Procedure
- Iron Chelation Procedure
- Hydroxyurea Drug
- Phlebotomy Procedure
Procedure · Drug
Eligibility (public fields only)
- Age range
- 5 Years to 18 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2006 (Type not available)
- Primary completion
- Jun 2010 (Actual)
- Completion
- Dec 2010 (Actual)
- Last update posted
- Jan 18, 2013
2006 – 2010
United States locations
- U.S. sites
- 28
- U.S. states
- 19
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010 | — |
| Nemours Children's Clinic | Jacksonville | Florida | 32207 | — |
| University of Miami, Jackson Memorial Hospital | Miami | Florida | 33136 | — |
| Nemours Children's Clinic | Orlando | Florida | 32806 | — |
| Children's Healthcare of Atlanta at Egleston | Atlanta | Georgia | 30322 | — |
| Children's Healthcare of Atlanta at Grady | Atlanta | Georgia | 30322 | — |
| Children's Healthcare of Atlanta at Scottish Rite | Atlanta | Georgia | 30342 | — |
| Children's Memorial Hospital | Chicago | Illinois | 60614 | — |
| Boston Children's Hospital | Boston | Massachusetts | 02115 | — |
| Wayne State University, Children's Hospital of Michigan | Detroit | Michigan | 48201 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| The Children's Mercy Hospital | Kansas City | Missouri | 64108 | — |
| St. Joseph's Children's Hospital | Paterson | New Jersey | 07503 | — |
| State University of New York/Downstate Medical Center | Brooklyn | New York | 11203 | — |
| Schneider Children's Hospital | New Hyde Park | New York | 11040 | — |
| Columbia University Medical Center, Morgan Stanley Children's Hospital of New York-Presbyterian | New York | New York | 10032 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| East Carolina University | Greenville | North Carolina | 27834 | — |
| Cincinnati Children's Hospital | Cincinnati | Ohio | 45229 | — |
| The Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Children's Hospital of Pittsburgh of UPMC | Pittsburgh | Pennsylvania | 15213 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| St. Jude Children's Research Hospital | Memphis | Tennessee | 38105 | — |
| University of Texas Southwestern Medical Center at Dallas | Dallas | Texas | 75390-9063 | — |
| Baylor College of Medicine | Houston | Texas | 77030-2399 | — |
| Eastern Virginia Medical School | Norfolk | Virginia | 23510 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00122980, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 18, 2013 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00122980 live on ClinicalTrials.gov.