Study of Abatacept (BMS-188667) in Subjects With Active Rheumatoid Arthritis on Background Non-biologic DMARDS (Disease Modifying Antirheumatic Drugs) Who Have an Inadequate Response to Anti-TNF Therapy
Public ClinicalTrials.gov record NCT00124982. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Multi-Center, Open Label Study to Evaluate the Efficacy, Tolerability and Safety of Abatacept (BMS-188667) in Subjects With Active Rheumatoid Arthritis on Background Non-Biologic DMARDs Who Have an Inadequate Response to Anti-TNF Therapy and Have Limited Therapeutic Options
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to summarize the safety and tolerability of abatacept during 6 months of combined treatment with one or more of the background non-biologic disease modifying anti-rheumatic drugs (DMARDs) approved for rheumatoid arthritis (RA) in subjects with active RA. Secondary objectives assessed the clinical efficacy of combination treatment, including disease activity, physical function, and quality of life outcomes.
Study identification
- NCT ID
- NCT00124982
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,286 participants
Conditions and interventions
Conditions
Interventions
- Abatacept Drug
- Non-biologic Disease Modifying Anti-Rheumatic Drug (DMARD) Drug
- Anti-Tumor Necrosing Factor (TNF) Therapy Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2005 (Type not available)
- Primary completion
- Aug 2009 (Actual)
- Completion
- Aug 2009 (Actual)
- Last update posted
- Feb 27, 2012
2005 – 2009
United States locations
- U.S. sites
- 114
- U.S. states
- 35
- U.S. cities
- 114
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution | Birmingham | Alabama | — | — |
| Local Institution | Huntsville | Alabama | — | — |
| Local Institution | Paradise Valley | Arizona | — | — |
| Local Institution | Peoria | Arizona | — | — |
| Local Institution | Tucson | Arizona | — | — |
| Local Institution | Long Beach | California | — | — |
| Local Institution | Palm Springs | California | — | — |
| Local Institution | Palo Alto | California | — | — |
| Local Institution | San Diego | California | — | — |
| Local Institution | Santa Monica | California | — | — |
| Local Institution | Colorado Springs | Colorado | — | — |
| Local Institution | Denver | Colorado | — | — |
| Local Institution | Danbury | Connecticut | — | — |
| Local Institution | Hamden | Connecticut | — | — |
| Local Institution | Trumbull | Connecticut | — | — |
| Local Institution | Washington D.C. | District of Columbia | — | — |
| Local Institution | Aventura | Florida | — | — |
| Local Institution | Clearwater | Florida | — | — |
| Local Institution | Fort Lauderdale | Florida | — | — |
| Local Institution | Jupiter | Florida | — | — |
| Local Institution | Largo | Florida | — | — |
| Local Institution | Sarasota | Florida | — | — |
| Local Institution | Atlanta | Georgia | — | — |
| Local Institution | Blue Ridge | Georgia | — | — |
| Local Institution | Macon | Georgia | — | — |
| Local Institution | Morton Grove | Illinois | — | — |
| Local Institution | Evansville | Indiana | — | — |
| Local Institution | Indianapolis | Indiana | — | — |
| Local Institution | Des Moines | Iowa | — | — |
| Local Institution | Kansas City | Kansas | — | — |
| Local Institution | Prairie Village | Kansas | — | — |
| Local Institution | Bowling Green | Kentucky | — | — |
| Local Institution | Louisville | Kentucky | — | — |
| Local Institution | New Orleans | Louisiana | — | — |
| Local Institution | Boston | Massachusetts | — | — |
| Local Institution | Peabody | Massachusetts | — | — |
| Local Institution | Springfield | Massachusetts | — | — |
| Local Institution | Worcester | Massachusetts | — | — |
| Local Institution | Ann Arbor | Michigan | — | — |
| Local Institution | East Lansing | Michigan | — | — |
| Local Institution | Grand Rapids | Michigan | — | — |
| Local Institution | Lansing | Michigan | — | — |
| Local Institution | Petockey | Michigan | — | — |
| Local Institution | Minneapolis | Minnesota | — | — |
| Local Institution | Saint Paul | Minnesota | — | — |
| Local Institution | Omaha | Nebraska | — | — |
| Local Institution | Las Vegas | Nevada | — | — |
| Local Institution | Lebanon | New Hampshire | — | — |
| Local Institution | Nashua | New Hampshire | — | — |
| Local Institution | Cherry Hill | New Jersey | — | — |
| Local Institution | Dover | New Jersey | — | — |
| Local Institution | Manalapan | New Jersey | — | — |
| Local Institution | New Brunswick | New Jersey | — | — |
| Local Institution | Somerset | New Jersey | — | — |
| Local Institution | Teaneck | New Jersey | — | — |
| Local Institution | Voorhees Township | New Jersey | — | — |
| Local Institution | Albany | New York | — | — |
| Local Institution | Brooklyn | New York | — | — |
| Local Institution | Hewlett | New York | — | — |
| Local Institution | Lake Success | New York | — | — |
| Local Institution | Mineola | New York | — | — |
| Local Institution | New York | New York | — | — |
| Local Institution | Olean | New York | — | — |
| Local Institution | Orchard Park | New York | — | — |
| Local Institution | Rochester | New York | — | — |
| Local Institution | Schenectady | New York | — | — |
| Local Institution | Smithtown | New York | — | — |
| Local Institution | Syracuse | New York | — | — |
| Local Institution | Asheville | North Carolina | — | — |
| Local Institution | Charlotte | North Carolina | — | — |
| Local Institution | Hickory | North Carolina | — | — |
| Local Institution | Wilmington | North Carolina | — | — |
| Local Institution | Bismarck | North Dakota | — | — |
| Local Institution | Akron | Ohio | — | — |
| Local Institution | Beachwood | Ohio | — | — |
| Local Institution | Cleveland | Ohio | — | — |
| Local Institution | Columbus | Ohio | — | — |
| Local Institution | Mayfield Village | Ohio | — | — |
| Local Institution | Youngstown | Ohio | — | — |
| Local Institution | Portland | Oregon | — | — |
| Local Institution | Bala-Cynwyd | Pennsylvania | — | — |
| Local Institution | Bethlehem | Pennsylvania | — | — |
| Local Institution | Camp Hill | Pennsylvania | — | — |
| Local Institution | Duncansville | Pennsylvania | — | — |
| Local Institution | Erie | Pennsylvania | — | — |
| Local Institution | Meadville | Pennsylvania | — | — |
| Local Institution | Philadelphia | Pennsylvania | — | — |
| Local Institution | Pittsburgh | Pennsylvania | — | — |
| Local Institution | West Reading | Pennsylvania | — | — |
| Local Institution | Wexford | Pennsylvania | — | — |
| Local Institution | Willow Grove | Pennsylvania | — | — |
| Local Institution | Providence | Rhode Island | — | — |
| Local Institution | Myrtle Beach | South Carolina | — | — |
| Local Institution | Simpsonville | South Carolina | — | — |
| Local Institution | Sioux Falls | South Dakota | — | — |
| Local Institution | Hixson | Tennessee | — | — |
| Local Institution | Knoxville | Tennessee | — | — |
| Local Institution | Austin | Texas | — | — |
| Local Institution | Corpus Christi | Texas | — | — |
| Local Institution | Dallas | Texas | — | — |
| Local Institution | Galveston | Texas | — | — |
| Local Institution | Houston | Texas | — | — |
| Local Institution | Lubbock | Texas | — | — |
| Local Institution | San Antonio | Texas | — | — |
| Local Institution | Sugarland | Texas | — | — |
| Local Institution | Burke | Virginia | — | — |
| Local Institution | Chesapeake | Virginia | — | — |
| Local Institution | Fairfax | Virginia | — | — |
| Local Institution | Salem | Virginia | — | — |
| Local Institution | Seattle | Washington | — | — |
| Local Institution | Vancouver | Washington | — | — |
| Local Institution | Glendale | Wisconsin | — | — |
| Local Institution | La Crosse | Wisconsin | — | — |
| Local Institution | Madison | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 34 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00124982, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 27, 2012 · Synced Nov 3, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00124982 live on ClinicalTrials.gov.