ClinicalTrials.gov record
Erlotinib Hydrochloride With or Without Carboplatin and Paclitaxel in Treating Patients With Stage III-IV Non-small Cell Lung Cancer
ClinicalTrials.gov ID: NCT00126581
Public ClinicalTrials.gov record NCT00126581. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Randomized Study of OSI-774 (Erlotinib) (NSC #718781) With or Without Carboplatin/Paclitaxel in Patients With Previously Untreated Adenocarcinoma of the Lung Who Never Smoked or Were Former Light Smokers
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This randomized phase II trial studies how well erlotinib hydrochloride with or without carboplatin and paclitaxel works in treating patients with stage III-IV non-small cell lung cancer. Erlotinib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving erlotinib hydrochloride together with carboplatin and paclitaxel may kill more tumor cells than giving either drug alone.
Study identification
- NCT ID
- NCT00126581
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 188 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 15, 2005 (Actual)
- Primary completion
- Jun 30, 2010 (Actual)
- Completion
- Nov 28, 2017 (Actual)
- Last update posted
- Aug 7, 2019
2005 – 2017
United States locations
- U.S. sites
- 96
- U.S. states
- 26
- U.S. cities
- 71
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| East Bay Radiation Oncology Center | Castro Valley | California | 94546 | — |
| Eden Hospital Medical Center | Castro Valley | California | 94546 | — |
| Valley Medical Oncology Consultants-Castro Valley | Castro Valley | California | 94546 | — |
| Bay Area Breast Surgeons Inc | Emeryville | California | 94608 | — |
| Valley Medical Oncology Consultants-Fremont | Fremont | California | 94538 | — |
| Saint Rose Hospital | Hayward | California | 94545 | — |
| Contra Costa Regional Medical Center | Martinez | California | 94553-3156 | — |
| El Camino Hospital | Mountain View | California | 94040 | — |
| Highland General Hospital | Oakland | California | 94602 | — |
| Alta Bates Summit Medical Center - Summit Campus | Oakland | California | 94609 | — |
| Bay Area Tumor Institute | Oakland | California | 94609 | — |
| Hematology and Oncology Associates-Oakland | Oakland | California | 94609 | — |
| Tom K Lee Inc | Oakland | California | 94609 | — |
| Valley Care Health System - Pleasanton | Pleasanton | California | 94588 | — |
| Valley Medical Oncology Consultants | Pleasanton | California | 94588 | — |
| University of California San Diego | San Diego | California | 92103 | — |
| Kaiser Permanente-San Diego Mission | San Diego | California | 92108 | — |
| Veterans Administration-San Diego Medical Center | San Diego | California | 92161 | — |
| UCSF Medical Center-Mount Zion | San Francisco | California | 94115 | — |
| Doctors Medical Center- JC Robinson Regional Cancer Center | San Pablo | California | 94806 | — |
| Middlesex Hospital | Middletown | Connecticut | 06457 | — |
| Beebe Medical Center | Lewes | Delaware | 19958 | — |
| Christiana Care Health System-Christiana Hospital | Newark | Delaware | 19718 | — |
| MedStar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| MedStar Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Holy Cross Hospital | Fort Lauderdale | Florida | 33308 | — |
| Jupiter Medical Center | Jupiter | Florida | 33458 | — |
| Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| Memorial Health University Medical Center | Savannah | Georgia | 31404 | — |
| University of Chicago Comprehensive Cancer Center | Chicago | Illinois | 60637 | — |
| AMITA Health Adventist Medical Center | La Grange | Illinois | 60525 | — |
| Elkhart General Hospital | Elkhart | Indiana | 46515 | — |
| Community Howard Regional Health | Kokomo | Indiana | 46904 | — |
| IU Health La Porte Hospital | La Porte | Indiana | 46350 | — |
| Saint Joseph Regional Medical Center-Mishawaka | Mishawaka | Indiana | 46545 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| Northern Indiana Cancer Research Consortium | South Bend | Indiana | 46628 | — |
| University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa | 52242 | — |
| University of Maryland/Greenebaum Cancer Center | Baltimore | Maryland | 21201 | — |
| MedStar Franklin Square Medical Center/Weinberg Cancer Institute | Baltimore | Maryland | 21237 | — |
| Union Hospital of Cecil County | Elkton | Maryland | 21921 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Mass General/North Shore Cancer Center | Danvers | Massachusetts | 01923 | — |
| Cape Cod Hospital | Hyannis | Massachusetts | 02601 | — |
| Lowell General Hospital | Lowell | Massachusetts | 01854 | — |
| South Shore Hospital | South Weymouth | Massachusetts | 02190 | — |
| Lakeland Medical Center Saint Joseph | Saint Joseph | Michigan | 49085 | — |
| University of Minnesota/Masonic Cancer Center | Minneapolis | Minnesota | 55455 | — |
| Missouri Cancer Associates | Columbia | Missouri | 65201 | — |
| Veterans Administration | Columbia | Missouri | 65201 | — |
| University of Missouri - Ellis Fischel | Columbia | Missouri | 65212 | — |
| Capital Region Medical Center | Jefferson City | Missouri | 65101 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Missouri Baptist Medical Center | St Louis | Missouri | 63131 | — |
| Center for Cancer Care and Research | St Louis | Missouri | 63141 | — |
| CHI Health Saint Francis | Grand Island | Nebraska | 68803 | — |
| Great Plains Health Callahan Cancer Center | North Platte | Nebraska | 69101 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| University Medical Center of Southern Nevada | Las Vegas | Nevada | 89102 | — |
| Saint Joseph Hospital | Nashua | New Hampshire | 03060 | — |
| Cooper Hospital University Medical Center | Camden | New Jersey | 08103 | — |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08903 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Hematology Oncology Associates of Central New York-East Syracuse | East Syracuse | New York | 13057 | — |
| Northwell Health NCORP | Lake Success | New York | 11042 | — |
| North Shore University Hospital | Manhasset | New York | 11030 | — |
| Long Island Jewish Medical Center | New Hyde Park | New York | 11040 | — |
| Ralph Lauren Center for Cancer Care and Prevention | New York | New York | 10035 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| Saint Joseph's Hospital Health Center | Syracuse | New York | 13203 | — |
| State University of New York Upstate Medical University | Syracuse | New York | 13210 | — |
| UNC Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | 27599 | — |
| Novant Health Presbyterian Medical Center | Charlotte | North Carolina | 28204 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Wayne Memorial Hospital | Goldsboro | North Carolina | 27534 | — |
| Wayne Radiation Oncology | Goldsboro | North Carolina | 27534 | — |
| Margaret R Pardee Memorial Hospital | Hendersonville | North Carolina | 28791 | — |
| Vidant Oncology-Kinston | Kinston | North Carolina | 28501 | — |
| Wilson Medical Center | Wilson | North Carolina | 27893 | — |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Cancer Care Associates | Oklahoma City | Oklahoma | 73120 | — |
| Memorial Hospital of Rhode Island | Pawtucket | Rhode Island | 02860 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Miriam Hospital | Providence | Rhode Island | 02906 | — |
| Roper Hospital | Charleston | South Carolina | 29401 | — |
| McLeod Regional Medical Center | Florence | South Carolina | 29506 | — |
| Saint Francis Hospital | Greenville | South Carolina | 29601 | — |
| Greenville Memorial Hospital | Greenville | South Carolina | 29605 | — |
| Greenville Health System Cancer Institute-Eastside | Greenville | South Carolina | 29615 | — |
| Central Vermont Medical Center/National Life Cancer Treatment | Berlin Corners | Vermont | 05602 | — |
| University of Vermont and State Agricultural College | Burlington | Vermont | 05405 | — |
| Rappahannock General Hospital | Kilmarnock | Virginia | 22482 | — |
| Virginia Commonwealth University/Massey Cancer Center | Richmond | Virginia | 23298 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00126581, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 7, 2019 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00126581 live on ClinicalTrials.gov.