ClinicalTrials.gov record
Toremifene Citrate for Prevention of Bone Fractures in Men With Prostate Cancer on Androgen Deprivation Therapy
ClinicalTrials.gov ID: NCT00129142
Public ClinicalTrials.gov record NCT00129142. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double Blind, Placebo Controlled, Multicenter Efficacy and Safety Study of Toremifene Citrate for Prevention of Bone Fractures in Men With Prostate Cancer on Androgen Deprivation Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Androgen deprivation therapy (ADT) treatment for prostate cancer decreases the natural hormone called testosterone. This type of therapy is very effective for the treatment of prostate cancer. However, one of the side effects is bone loss or thinning of the bones that can lead to osteoporosis and an increased risk of bone fractures (breaking of the bones). The purpose of the study is to determine whether or not the addition of toremifene citrate (the study drug) to therapy can prevent or decrease the number of bone fractures and to evaluate its impact on side effects associated with testosterone reduction therapy.
Study identification
- NCT ID
- NCT00129142
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,200 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2003 (Type not available)
- Primary completion
- Nov 2007 (Actual)
- Completion
- Nov 2007 (Actual)
- Last update posted
- Nov 15, 2013
2003 – 2007
United States locations
- U.S. sites
- 136
- U.S. states
- 37
- U.S. cities
- 120
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Urology Centers of Alabama | Homewood | Alabama | 35209 | — |
| Coastal Clinical Research | Mobile | Alabama | 36608 | — |
| Arkansas Urology | Little Rock | Arkansas | 72211 | — |
| Advanced Urology Medical Center Clinical Trials | Anaheim | California | 92801 | — |
| Urological Sciences Research Foudation | Culver City | California | 90232 | — |
| Urological Associates of Central CA | Fresno | California | 93720 | — |
| Center of Urologic Research | La Mesa | California | 91942 | — |
| South Orange County Medical Research Center | Laguna Woods | California | 92653 | — |
| Palo Alto VA | Palo Alto | California | 94305 | — |
| San Bernadino Urological Associates | San Bernadino | California | 92404 | — |
| Urological Physicians of San Diego | San Diego | California | 92103 | — |
| Veterans Medical Research Foundation | San Diego | California | 92161 | — |
| Pacific Clinical Research | Santa Monica | California | 90404 | — |
| West Coast Clinical Research | Tarzana | California | 91356 | — |
| Western Clinical Research, Inc. | Torrance | California | 90505 | — |
| Urology Associates | Denver | Colorado | 80210 | — |
| Western Urological Research | Wheat Ridge | Colorado | 80033 | — |
| Urologic Center | New Haven | Connecticut | 06511 | — |
| Urological Associates of Bridgeport | Trumball | Connecticut | 06611 | — |
| Connecticut Clinical Research | Waterbury | Connecticut | 06708 | — |
| Walter Reed Army Medical Center | Washington D.C. | District of Columbia | 20307 | — |
| South Florida Medical Research | Aventura | Florida | 33180 | — |
| Urology Consultants Inc. | Clearwater | Florida | 33761 | — |
| Atlantic Urological Associates | Daytona Beach | Florida | 32114 | — |
| Urosearch | Inverness | Florida | 34452 | — |
| Lakeland Regional Medical Center | Lakeland | Florida | 33805 | — |
| Advance Research Institute | New Port Richey | Florida | 34652 | — |
| Central Florida Urology Group/ UroSearch | Ocala | Florida | 34474 | — |
| Florida Foundation for Healthcare Research | Ocala | Florida | 34474 | — |
| Winter Park Urology Associates | Orlando | Florida | 32803 | — |
| Panama City Urology | Panama City Beach | Florida | 32405 | — |
| Pinellas Urology | St. Petersburg | Florida | 33710 | — |
| Southeastern Research Group | Tallahassee | Florida | 32308 | — |
| Tampa Bay Urology | Tampa | Florida | 33607 | — |
| UroSearch | Tavares | Florida | 32778 | — |
| Cleveland Clinic-Florida | Weston | Florida | 33331 | — |
| Midtown Urology | Atlanta | Georgia | 30308 | — |
| Georgia Urology | Atlanta | Georgia | 30342 | — |
| St. Joseph Research Institute | Atlanta | Georgia | 30342 | — |
| Augusta VAMC | Augusta | Georgia | 30912 | — |
| Southeastern Medical Research Institute | Columbus | Georgia | 31904 | — |
| Urology Enterprises | Marietta | Georgia | 30060 | — |
| Harbin Clinic Department of Urology Research | Rome | Georgia | 30165 | — |
| North Fulton Urology | Roswell | Georgia | 30076 | — |
| St. Joseph's, Candler Health System | Savannah | Georgia | 31405 | — |
| North Idaho Urology | Coeur d'Alene | Idaho | 83814 | — |
| Prairie Medical Associates | Chicago | Illinois | 60616 | — |
| Medical and Surgical Specialists | Galesburg | Illinois | 61401 | — |
| Special Care Research | Peoria | Illinois | 61614 | — |
| Urology of Indiana, LLC | Greenwood | Indiana | 46143 | — |
| MMPC Urology | Greenwood | Indiana | 49546 | — |
| Metropolitan Urology | Jeffersonville | Indiana | 47130 | — |
| Heartland Research Associates, LLC | Wichita | Kansas | 67207 | — |
| LSUHSC/Stanley Scott Cancer Center | New Orleans | Louisiana | 70112 | — |
| Regional Urology LLC | Shreveport | Louisiana | 71106 | — |
| Anne Arundel Urology P.A. | Annapolis | Maryland | 21401 | — |
| Maryland Prostate Center: University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Urology Center, PA | Hagerstown | Maryland | 21742 | — |
| Mid Atlantic Clinical Research | Rockville | Maryland | 28050 | — |
| The Fallon Clinic | Worcester | Massachusetts | 01605 | — |
| Wayne Glazier | Worcester | Massachusetts | 01605 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109 | — |
| Beaumont Medical | Royal Oak | Michigan | 48073 | — |
| Mayo Clinic Urology Department | Rochester | Minnesota | 55905 | — |
| Park Nicollet Urology | Saint Louis Park | Minnesota | 55416 | — |
| Kansas City Urology, PC | Kansas City | Missouri | 64131 | — |
| PPS Clinical Research | St Louis | Missouri | 63141 | — |
| Urologic Research Center | St Louis | Missouri | 63141 | — |
| Sheldon Freeman | Las Vegas | Nevada | 89109 | — |
| Urologic Surgeons, Ltd. | Reno | Nevada | 89502 | — |
| Coastal Urology Associates | Brick | New Jersey | 08724 | — |
| Hamilton Urology PA | Hamilton | New Jersey | 08690 | — |
| Lawrenceville Urology Associates | Lawrenceville | New Jersey | 08648 | — |
| Assoc. Urologic Specialists | Marlton | New Jersey | 08053 | — |
| Urology Healthcare Associates | Willingboro | New Jersey | 08046 | — |
| Urology Group of New Mexico | Albuquerque | New Mexico | 87109 | — |
| Urology Inst. Of New York | Albany | New York | 12208 | — |
| William Oberheim | Albany | New York | 12208 | — |
| Metropolitan Urologic Services, PC | Elmont | New York | 11003 | — |
| Urological Surgeons of Long Island | Garden City | New York | 11530 | — |
| University Urology Associates | New York | New York | 10016 | — |
| Mount Sinai School of Medicine | New York | New York | 10029 | — |
| CNY Urology | Oneida | New York | 13421 | — |
| Staten Island Urological Research , PC | Staten Island | New York | 10304 | — |
| Associated Urologists of CNY | Syracuse | New York | 13210 | — |
| Center for Urologic Research WNY, LLC | Williamsville | New York | 14221 | — |
| Asheboro Urology | Asheboro | North Carolina | 27203 | — |
| University of North Carolina | Chapel Hill | North Carolina | 27559 | — |
| The Urology Center | Greensboro | North Carolina | 27403 | — |
| Wake Urology | Raleigh | North Carolina | 27607 | — |
| Piedmont Medical Research Associates | Winston-Salem | North Carolina | 27103 | — |
| Odyssey Research | Bismarck | North Dakota | 58501 | — |
| Summa Health Care | Akron | Ohio | 44304 | — |
| The Urology Group | Cincinnati | Ohio | 45212 | — |
| Cleveland Clinic Lerner College of Medicine | Cleveland | Ohio | 44195 | — |
| Colombus Urology Research | Columbus | Ohio | 43214 | — |
| Urology of Northern Ohio | Elyria | Ohio | 44035 | — |
| Southwest Urology | Parma | Ohio | 44129 | — |
| Oklahoma University Medical Center | Oklahoma City | Oklahoma | 73104 | — |
| Urologic Specialists of Oklahoma, Inc. | Tulsa | Oklahoma | 12208 | — |
| The Corvallis Clinic | Corvallis | Oregon | 97330 | — |
| Oregon Urology Specialists | Springfield | Oregon | 97477 | — |
| Urologic Associates of Allentown | Allentown | Pennsylvania | 18103 | — |
| Urologic Surgery | Bala-Cynwyd | Pennsylvania | 19004 | — |
| Urological Associates of Lancaster, Ltd. | Lancaster | Pennsylvania | 17604 | — |
| The Urology Institute | Monroeville | Pennsylvania | 15146 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Ginsberg and Harkaway Urology | Philadelphia | Pennsylvania | 19141 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15232 | — |
| State College Urologic Association | State College | Pennsylvania | 16801 | — |
| University Urological Research Institute | Providence | Rhode Island | 02904 | — |
| Radiant Research | Greer | South Carolina | 29651 | — |
| Carolina Urologic Research Center | Myrtle Beach | South Carolina | 29572 | — |
| Volunteer Research Group | Knoxville | Tennessee | 37920 | — |
| Southeast Urology Network | Memphis | Tennessee | 38119 | — |
| Ace Research Specialists | Nashville | Tennessee | 37203 | — |
| Center for Urological Treatment | Nashville | Tennessee | 37203 | — |
| Urology Associates | Nashville | Tennessee | 37209 | — |
| Vanderbilt Medical Center | Nashville | Tennessee | 37232 | — |
| Professional Quality Research | Austin | Texas | 78756 | — |
| Breco Research | Houston | Texas | 77024 | — |
| Urology Consultants, PA | San Antonio | Texas | 78229 | — |
| Urology San Antonio Research, PA | San Antonio | Texas | 78229 | — |
| Scott and White Clinical Hospital | Temple | Texas | 76508 | — |
| Salt Lake City Research | Salt Lake City | Utah | 84124 | — |
| Adult and Pediatric Urologists of Northern VA | Alexandria | Virginia | 22304 | — |
| Devine Tidewater Urology | Norfolk | Virginia | 23502 | — |
| Med Atlantic, Inc (Virginia Urology) | Richmond | Virginia | 23235 | — |
| McGuire VA Medical Center | Richmond | Virginia | 23249 | — |
| Seattle VAMC | Seattle | Washington | 98108 | — |
| Deaconess Medical Center | Spokane | Washington | 99204 | — |
| Madigan Army Medical Center | Tacoma | Washington | 98431 | — |
| University of Wisconsin Medical School: Clinical Trials | Madison | Wisconsin | 53715 | — |
| St. Michael's Hospital | Milwaukee | Wisconsin | 53209 | — |
| Froedtert Memorial Lutheran Hospital Department of Urology | Milwaukee | Wisconsin | 53226 | — |
| Wyoming Research Foundation | Cheyenne | Wyoming | 82001 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 19 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00129142, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 15, 2013 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00129142 live on ClinicalTrials.gov.