The SEPIA-PCI Trial: Otamixaban in Comparison to Heparin in Subjects Undergoing Non-Urgent Percutaneous Coronary Intervention
Public ClinicalTrials.gov record NCT00133731. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multinational, Randomized, Double-Blind, Double-Dummy, Exploratory, Parallel Group, Dose-Ranging Phase II Study to Evaluate Pharmacodynamics, Safety and Tolerability, and Pharmacokinetics of Several Intravenous Regimens of Factor Xa Inhibitor Otamixaban (XRP0673), in Comparison to Intravenous Unfractionated Heparin, in Subjects Undergoing Non-Urgent Percutaneous Coronary Intervention
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this dose-ranging study is to determine the effects of several intravenous (IV) regimens of otamixaban on pharmacodynamic markers (including markers of thrombosis and coagulation markers), safety/tolerability, clinical efficacy and pharmacokinetics.
Study identification
- NCT ID
- NCT00133731
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 947 participants
Conditions and interventions
Interventions
- Otamixaban (XRP0673) Drug
- Unfractionated Heparin Drug
- Percutaneous Coronary Intervention Procedure
Drug · Procedure
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2004 (Type not available)
- Primary completion
- Not listed
- Completion
- Oct 2005 (Actual)
- Last update posted
- Jul 2, 2008
2004 – 2005
United States locations
- U.S. sites
- 37
- U.S. states
- 19
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Los Angeles Cardiology Associates | Los Angeles | California | 90017 | — |
| Anil V. Shah, MD | Santa Ana | California | 92704 | — |
| George Washington University Medical Faculty Associates | Washington D.C. | District of Columbia | 20037 | — |
| Florida Cardiovascular Research | Atlantis | Florida | 33462 | — |
| Ocala Research Institute, Inc | Ocala | Florida | 34480 | — |
| Central Florida Cardiology Group, PA | Orlando | Florida | 32803 | — |
| Cardiology Associates, PA | Panama City | Florida | 32401 | — |
| Heart Specialists of Sarasota | Sarasota | Florida | 34239 | — |
| Cardiac Disease Specialists | Atlanta | Georgia | 30309 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Midwest Heart Foundation | Lombard | Illinois | 60148 | — |
| Loyola University Medical Center | Maywood | Illinois | 61053 | — |
| Heart Care Midwest | Peoria | Illinois | 61603 | — |
| Prairie Cardiovascular Consultants, Ltd | Springfield | Illinois | 62702 | — |
| The Care Group, LLC | Indianapolis | Indiana | 46290 | — |
| Iowa Heart Center, PC | Des Moines | Iowa | 50314 | — |
| Kansas Cardiology Associates | Wichita | Kansas | 67214 | — |
| UMass Memorial Medical Center | Worcester | Massachusetts | 01605-0002 | — |
| Minneapolis Heart Institute Foundation | Minneapolis | Minnesota | 55407 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | — |
| LeBauer Cardiovascular Research Foundation | Greensboro | North Carolina | 27401 | — |
| Wake Heart Associates | Raleigh | North Carolina | 27610 | — |
| The Lindner Clinical Trial Center | Cincinnati | Ohio | 45219 | — |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| University of Oklahoma Health Science Center | Oklahoma City | Oklahoma | 73104 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Plaza Medical Group, PC | Oklahoma City | Oklahoma | 73112 | — |
| Geisinger Clinic | Danville | Pennsylvania | 17822-2160 | — |
| Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| University of Pennsylvania Health System | Philadelphia | Pennsylvania | 19104 | — |
| Columbia Heart Clinic | Columbia | South Carolina | 29203 | — |
| Amarillo Heart Clinical Research Institute Inc | Amarillo | Texas | 79106 | — |
| MEDVAMC | Houston | Texas | 77030 | — |
| Audie Murphy VA Medical Center | San Antonio | Texas | 78229 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298-0036 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 52 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00133731, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 2, 2008 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00133731 live on ClinicalTrials.gov.