Cidofovir in Renal Transplant Recipients With BKVN
Public ClinicalTrials.gov record NCT00138424. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Placebo-Controlled, Dose-Escalation Study to Assess the Safety and Effect of Cidofovir in Renal Transplant Recipients With BK Virus Nephropathy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will look at the safety, tolerability and effectiveness of cidofovir in kidney transplant patients who have been diagnosed with BK virus nephropathy (BKVN), a viral condition that can cause patients to reject transplanted kidneys. Up to 48 adult (age 18 years and older) kidney or pancreas transplant recipients with newly diagnosed BKVN will receive 1 of 3 cidofovir dose levels or placebo (non medicated substance) to identify the maximum tolerated dose. Dosing will be administered intravenously (by a tube running into a blood vessel). In addition to the screening visit, volunteers will actively participate for approximately 8-10 weeks with a single follow up phone call at 4 months. Blood samples, urine samples, eye exams and physical exams are included in study procedures.
Study identification
- NCT ID
- NCT00138424
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 22 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2006 (Type not available)
- Primary completion
- Jun 2010 (Actual)
- Completion
- Apr 2011 (Actual)
- Last update posted
- Mar 8, 2013
2006 – 2011
United States locations
- U.S. sites
- 12
- U.S. states
- 9
- U.S. cities
- 10
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Hospital - Nephrology | Birmingham | Alabama | 35249-0001 | — |
| California Pacific Medical Center - Sutter Pacific Medical Foundation - Transplant Nephrology | San Francisco | California | 94115-1932 | — |
| University of California San Francisco Medical Center at Parnassus - Organ Transplant | San Francisco | California | 94143-2204 | — |
| University of Colorado Denver | Aurora | Colorado | 80045-2541 | — |
| Northwestern University - Comprehensive Transplant Center | Chicago | Illinois | 60611-2927 | — |
| The University of Chicago Medical Center - Kindney Trasnplant - Nephrology | Chicago | Illinois | 60637-1447 | — |
| University of Minnesota Medical Center, Fairview - Infectious Diseases and International Medicine | Minneapolis | Minnesota | 55455-0356 | — |
| Mayo Clinic, Rochester - Infectious Diseases | Rochester | Minnesota | 55905-0001 | — |
| Dartmouth-Hitchcock Medical Center - Infectious Disease | Lebanon | New Hampshire | 03756-1000 | — |
| Dallas Nephrology Associates - Dallas Transplant Institute | Dallas | Texas | 75204-6168 | — |
| University of Washington - Medicine | Seattle | Washington | 98195-7110 | — |
| University of Wisconsin Hospital and Clinics - Clinical Science Center - Nephrology | Madison | Wisconsin | 53792-0001 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00138424, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 8, 2013 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00138424 live on ClinicalTrials.gov.