Study of STA-5326 Mesylate in Patients With Moderate to Severe Crohn's Disease
Public ClinicalTrials.gov record NCT00138840. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Clinical Study of the Oral IL-12/23 Inhibitor, STA-5326 Mesylate, for the Induction of Clinical Response in Patients With Crohn's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
STA-5326 is an experimental drug that has been shown to block the release of interleukin-12 from peripheral blood mononuclear cells. Given this activity on the immune system, STA-5326 mesylate is a potential treatment for various autoimmune diseases, such as Crohn's disease, that are mediated by the inappropriate expression of Th1 cytokines. This study is evaluating the use of STA-5326 mesylate in patients with moderate to severe, active Crohn's disease. Study visits include a screening visit, 9 treatment period visits over 6 months and a follow-up visit that will occur 30 days following the end of treatment. Study drug treatment will continue for up to 6 months.
Study identification
- NCT ID
- NCT00138840
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 282 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 31, 2005
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Dec 3, 2008
Started 2005
United States locations
- U.S. sites
- 31
- U.S. states
- 17
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Gastroenterology Associates | Little Rock | Arkansas | 72205 | — |
| Advanced Clinical Research Institute | Anaheim | California | 92801 | — |
| Community Clinical Trials | Orange | California | 92868 | — |
| Medical Associates Research Group | San Diego | California | 92123 | — |
| Southern Clinical Research Consultants | Hollywood | Florida | 33021 | — |
| Borland Groover Clinic | Jacksonville | Florida | 32204 | — |
| Miami Research Associates | Miami | Florida | 33173 | — |
| Advanced Gastroenterology Highland Lakes Medical Center | Palm Harbor | Florida | 34684 | — |
| Shafran Gastroenterology Center | Winter Park | Florida | 32789 | — |
| Atlanta Gastroenterology | Atlanta | Georgia | 30342 | — |
| Univ. of Louisville Clinical Research Unit | Louisville | Kentucky | 40202 | — |
| Chevy Chase Clinical Research | Chevy Chase | Maryland | 20815 | — |
| Maryland Digestive Disease Research | Laurel | Maryland | 20707 | — |
| Capital Gastroenterology Consultants, P.A. | Silver Spring | Maryland | 20901 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| St. Louis Center for Clinical Research | St Louis | Missouri | 63128 | — |
| Gastroenterology Research Associates | Cedar Knolls | New Jersey | 07927 | — |
| Asher Kornbluth, MD | New York | New York | 10128 | — |
| Rochester Institute for Digestive Diseases and Sciences, Inc. | Rochester | New York | 14607 | — |
| Asheville Gastroenterology Associates, PA | Asheville | North Carolina | 28801 | — |
| Carolina Digestive Health Associates | Charlotte | North Carolina | 28211 | — |
| Pinehurst Medical Clinic | Pinehurst | North Carolina | 28374 | — |
| Wake Research Associates, LLC. | Raleigh | North Carolina | 27612 | — |
| Piedmont Medical Research Associates | Winston-Salem | North Carolina | 27103 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Columbia Gastroenterology Associates, P.A. | Columbia | South Carolina | 29203 | — |
| Gastroenterology Center of the MidSouth | Germantown | Tennessee | 38138 | — |
| Nashville Medical Research Institute | Nashville | Tennessee | 37205 | — |
| Austin Gastroenterology | Austin | Texas | 78745 | — |
| New River Valley Research Institute | Christiansburg | Virginia | 24073 | — |
| Wisconsin Center for Advanced Research | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00138840, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 3, 2008 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00138840 live on ClinicalTrials.gov.