Study of STA-5326 Mesylate in Patients With Moderate to Severe Crohn's Disease
Public ClinicalTrials.gov record NCT00138840. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Randomized, Double-Blind, Placebo-Controlled Clinical Study of the Oral IL-12/23 Inhibitor, STA-5326 Mesylate, for the Induction of Clinical Response in Patients With Crohn's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
STA-5326 is an experimental drug that has been shown to block the release of interleukin-12 from peripheral blood mononuclear cells. Given this activity on the immune system, STA-5326 mesylate is a potential treatment for various autoimmune diseases, such as Crohn's disease, that are mediated by the inappropriate expression of Th1 cytokines. This study is evaluating the use of STA-5326 mesylate in patients with moderate to severe, active Crohn's disease. Study visits include a screening visit, 9 treatment period visits over 6 months and a follow-up visit that will occur 30 days following the end of treatment. Study drug treatment will continue for up to 6 months.
Study identification
- NCT ID
- NCT00138840
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 282 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2005 (Type not available)
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Dec 4, 2008
Started 2005
United States locations
- U.S. sites
- 31
- U.S. states
- 17
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Gastroenterology Associates | Little Rock | Arkansas | 72205 | — |
| Advanced Clinical Research Institute | Anaheim | California | 92801 | — |
| Community Clinical Trials | Orange | California | 92868 | — |
| Medical Associates Research Group | San Diego | California | 92123 | — |
| Southern Clinical Research Consultants | Hollywood | Florida | 33021 | — |
| Borland Groover Clinic | Jacksonville | Florida | 32204 | — |
| Miami Research Associates | Miami | Florida | 33173 | — |
| Advanced Gastroenterology Highland Lakes Medical Center | Palm Harbor | Florida | 34684 | — |
| Shafran Gastroenterology Center | Winter Park | Florida | 32789 | — |
| Atlanta Gastroenterology | Atlanta | Georgia | 30342 | — |
| Univ. of Louisville Clinical Research Unit | Louisville | Kentucky | 40202 | — |
| Chevy Chase Clinical Research | Chevy Chase | Maryland | 20815 | — |
| Maryland Digestive Disease Research | Laurel | Maryland | 20707 | — |
| Capital Gastroenterology Consultants, P.A. | Silver Spring | Maryland | 20901 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| St. Louis Center for Clinical Research | St Louis | Missouri | 63128 | — |
| Gastroenterology Research Associates | Cedar Knolls | New Jersey | 07927 | — |
| Asher Kornbluth, MD | New York | New York | 10128 | — |
| Rochester Institute for Digestive Diseases and Sciences, Inc. | Rochester | New York | 14607 | — |
| Asheville Gastroenterology Associates, PA | Asheville | North Carolina | 28801 | — |
| Carolina Digestive Health Associates | Charlotte | North Carolina | 28211 | — |
| Pinehurst Medical Clinic | Pinehurst | North Carolina | 28374 | — |
| Wake Research Associates, LLC. | Raleigh | North Carolina | 27612 | — |
| Piedmont Medical Research Associates | Winston-Salem | North Carolina | 27103 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Columbia Gastroenterology Associates, P.A. | Columbia | South Carolina | 29203 | — |
| Gastroenterology Center of the MidSouth | Germantown | Tennessee | 38138 | — |
| Nashville Medical Research Institute | Nashville | Tennessee | 37205 | — |
| Austin Gastroenterology | Austin | Texas | 78745 | — |
| New River Valley Research Institute | Christiansburg | Virginia | 24073 | — |
| Wisconsin Center for Advanced Research | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00138840, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 4, 2008 · Synced Nov 6, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00138840 live on ClinicalTrials.gov.