TBTC Study 27: Moxifloxacin vs Ethambutol for TB Treatment
Public ClinicalTrials.gov record NCT00140309. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
TBTC Study 27: An Evaluation of the Activity and Tolerability of Moxifloxacin During the First Two Months of Treatment for Pulmonary Tuberculosis--A Double-Blind, Randomized, Multicenter Study by the Tuberculosis Trials Consortium
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is a placebo-controlled factorial study, randomized to study drug (moxifloxacin vs. ethambutol) and treatment frequency (daily vs. thrice weekly after an initial two weeks of daily therapy) during the first two months of standard treatment (with isoniazid, rifampin, and pyrazinamide) for sputum smear-positive pulmonary tuberculosis.
Study identification
- NCT ID
- NCT00140309
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 350 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2003 (Type not available)
- Primary completion
- Not listed
- Completion
- Dec 2005 (Actual)
- Last update posted
- Mar 19, 2007
2003 – 2005
United States locations
- U.S. sites
- 18
- U.S. states
- 12
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Southern California Medical Center | Los Angeles | California | 90033 | — |
| University of California at San Diego | San Diego | California | 92103 | — |
| University of California, San Francisco | San Francisco | California | 94110 | — |
| Denver Public Health Department | Denver | Colorado | 80204 | — |
| Washington DC Veterans Administration Medical Center | Washington D.C. | District of Columbia | 20422 | — |
| Emory University School of Medicine | Atlanta | Georgia | 30303 | — |
| Hines Vetrans Administration Medical Center | Hines | Illinois | 60141 | — |
| Johns Hopkins University | Baltimore | Maryland | 21231 | — |
| Boston University Medical Center | Boston | Massachusetts | 02118 | — |
| New Jersey School of Medicine | Newark | New Jersey | 07107 | — |
| New York University School of Medicine | New York | New York | 10016 | — |
| Columbia University | New York | New York | 10032 | — |
| Harlem Hospital Center | New York | New York | 10037 | — |
| Veterans Administration Tennessee Valley Health Care System | Nashville | Tennessee | 37232 | — |
| University of North Texas Health Science Center | Fort Worth | Texas | 76104 | — |
| Houston Veterans Administration Medical Center | Houston | Texas | 77030 | — |
| Audie L Murphy Memorial Veterans Administration Medical Center | San Antonio | Texas | 78284 | — |
| Seattle-King County Health Department | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00140309, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 19, 2007 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00140309 live on ClinicalTrials.gov.