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Completed Phase 3 Interventional

Study to Establish Bioequivalence of ReFacto AF (BDDrFVIII) With Advate (FLrFVIII) in Hemophilia A

ClinicalTrials.gov ID: NCT00141843

Public ClinicalTrials.gov record NCT00141843. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 8, 2026, 12:27 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Two-Way Blinded Crossover-Design Study to Establish the Bioequivalence of B-Domain Deleted Recombinant Factor VIII (BDDrFVIII,Refacto AF) With a Full Length Recombinant Factor VIII Preparation (FLrFVIII,Advate), Followed by an Open-Label Trial of the Safety and Efficacy of ReFacto AF in Previously Treated Patients With Hemophilia A.

Study identification

NCT ID
NCT00141843
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Industry
Enrollment
100 participants

Conditions and interventions

Conditions

Interventions

  • B-Domain deleted Recombinant Factor VIII Genetic
  • BDDrFVIII Genetic
  • ReFacto AF Genetic

Genetic

Eligibility (public fields only)

Age range
12 Years and older
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 30, 2005
Primary completion
Oct 31, 2006
Completion
Oct 31, 2006
Last update posted
Apr 21, 2008

2005 – 2006

United States locations

U.S. sites
21
U.S. states
18
U.S. cities
21
Facility City State ZIP Site status
Not listed Phoenix Arizona 85016
Not listed Sacramento California 95817
Not listed San Diego California 92123
Not listed Aurora Colorado 80045
Not listed Atlanta Georgia 30322
Not listed Iowa City Iowa 52242
Not listed New Orleans Louisiana 70112
Not listed Worcester Massachusetts 01605
Not listed East Lansing Michigan 48823
Not listed St Louis Missouri 63014
Not listed New Brunswick New Jersey 08903-0019
Not listed Buffalo New York 14215
Not listed New Hyde Park New York 11040
Not listed Chapel Hill North Carolina 27599
Not listed Dayton Ohio 45404
Not listed Hershey Pennsylvania 17033
Not listed Philadelphia Pennsylvania
Not listed Nashville Tennessee 37232
Not listed Houston Texas 77030
Not listed Salt Lake City Utah 84113
Not listed Charlottesville Virginia 22908

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00141843, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 21, 2008 · Synced May 8, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00141843 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →